Search Results - "Pisani, Gerardo B."
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Adaptive downregulation of Cl-/HCO3- exchange activity in rat hepatocytes under experimental obstructive cholestasis
Published in PloS one (21-02-2019)“…In obstructive cholestasis, there is an integral adaptive response aimed to diminish the bile flow and minimize the injury of bile ducts caused by increased…”
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2
Hyperglycemia induces apoptosis in rat liver through the increase of hydroxyl radical: new insights into the insulin effect
Published in Journal of endocrinology (01-05-2010)“…AbstractIn this study, we analyzed the contribution of hydroxyl radical in the liver apoptosis mediated by hyperglycemia through the Bax–caspase pathway and…”
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3
Comparison of two chemical models to induce hepatic preneoplasia in male Wistar rats
Published in Annals of hepatology (01-03-2015)“…AbstractBackground. One established model to induce hepatic preneoplasia (HP) (DEN 150) uses diethylnitrosamine (DEN) as initiator agent and…”
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4
Localization and functional activity of cytochrome P450 side chain cleavage enzyme (CYP11A1) in the adult rat kidney
Published in Molecular and cellular endocrinology (30-01-2011)“…Cumulative evidence demonstrated effective downstream metabolism of pregnenolone in renal tissue. The aim of this study was to evaluate the expression and…”
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5
Impairment of renal steroidogenesis at the onset of diabetes
Published in Molecular and cellular endocrinology (15-03-2021)“…Accumulating evidence indicates the association between changes in circulating sex steroid hormone levels and the development of diabetic nephropathy. However,…”
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6
The chemoprotective effects of IFN-α-2b on rat hepatocarcinogenesis are blocked by vitamin E supplementation
Published in The Journal of nutritional biochemistry (01-10-2021)“…Many cancer patients receive their classical therapies together with vitamin supplements. However, the effectiveness of these strategies is on debate. Here we…”
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7
Vitamin K2 supplementation blocks the beneficial effects of IFN-α-2b administered on the early stages of liver cancer development in rats
Published in Nutrition (Burbank, Los Angeles County, Calif.) (01-03-2019)“…Vitamin K2, which is present in dairy products and has been recommended as a micronutrient supplement in humans, contains anticancer properties. Interferon…”
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8
Hepatic carboxylesterase 3 (Ces3/Tgh) is downregulated in the early stages of liver cancer development in the rat
Published in Biochimica et biophysica acta. Molecular basis of disease (01-11-2016)“…It is accepted that cancer development is associated with metabolic changes. Previously, we established a model of hepatic preneoplasia in which adult rats…”
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9
Attenuation of liver cancer development by oral glycerol supplementation in the rat
Published in European journal of nutrition (01-04-2018)“…Purpose Glycerol usage is increasing in food industry for human and animal nutrition. This study analyzed the impact of glycerol metabolism when orally…”
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10
Tumor necrosis factor alpha pathways develops liver apoptosis in type 1 diabetes mellitus
Published in Molecular immunology (01-07-2011)“…We analyzed the contribution of TNF-α intracellular pathway in the development of apoptosis in the liver of streptozotocin-induced diabetic rats. In liver…”
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11
FoxO3a modulation and promotion of apoptosis by interferon-α2b in rat preneoplastic liver
Published in Liver international (01-11-2014)“…Background FoxO3a, a member of the FOXO family of transcription factors, is expressed in adult liver and modulates the expression of genes involved in…”
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12
Role of reactive oxygen species in the early stages of liver regeneration in streptozotocin-induced diabetic rats
Published in Free radical research (01-10-2011)“…Diabetes mellitus is a risk factor for prognosis after liver resection. In previous work, we found a pro-apoptotic state in the diabetic rat liver. In this…”
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13
Involvement of oxidative stress in the impairment in biliary secretory function induced by intraperitoneal administration of aluminum to rats
Published in Biological trace element research (01-06-2007)“…We have shown that aluminum (Al) induces cholestasis associated with multiple alterations in hepatocellular transporters involved in bile secretory function,…”
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14
Tumor necrosis factor alpha induced by Trypanosoma cruzi infection mediates inflammation and cell death in the liver of infected mice
Published in Cytokine (Philadelphia, Pa.) (2010)“…Trypanosoma cruzi ( T. cruzi) infected C57BL/6 mice developed a progressive fatal disease due to an imbalance in the profile of circulating related compounds…”
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15
Heat shock protein 70 induction and its urinary excretion in a model of acetaminophen nephrotoxicity
Published in Pediatric nephrology (Berlin, West) (01-07-2010)“…Acetaminophen (APAP) is an analgesic–antipyretic drug widely used in children. In the present study, we used an in vivo model of APAP-induced nephrotoxicity in…”
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16
Involvement of reactive oxygen species on the apoptotic mechanism induced by IFN-α2b in rat preneoplastic liver
Published in Biochemical pharmacology (01-06-2007)“…Interferon-α2b (IFN-α2b) is an important component in the preventive treatment of patients who have severe hepatic illness such as hepatitis B or C and…”
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17
Interferon α‐induced apoptosis on rat preneoplastic liver is mediated by hepatocytic transforming growth factor β1
Published in Hepatology (Baltimore, Md.) (01-08-2004)“…In previous work we showed that interferon alfa‐2b (IFN‐α2b) increases apoptosis on rat hepatic preneoplastic foci. The aim of this study was to determine if…”
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18
Adaptive downregulation of Cl.sup.-/HCO.sub.3.sup.- exchange activity in rat hepatocytes under experimental obstructive cholestasis
Published in PloS one (21-02-2019)“…In obstructive cholestasis, there is an integral adaptive response aimed to diminish the bile flow and minimize the injury of bile ducts caused by increased…”
Get full text
Journal Article -
19
Vitamin K 2 supplementation blocks the beneficial effects of IFN-α-2b administered on the early stages of liver cancer development in rats
Published in Nutrition (Burbank, Los Angeles County, Calif.) (01-03-2019)“…Vitamin K , which is present in dairy products and has been recommended as a micronutrient supplement in humans, contains anticancer properties. Interferon…”
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Journal Article -
20
Attenuation of the Wnt/β-catenin/TCF pathway by in vivo interferon-α2b (IFN-α2b) treatment in preneoplastic rat livers
Published in Growth factors (Chur, Switzerland) (01-06-2010)“…Wnt/β-catenin/T cell factor (TCF) pathway is activated in several types of human cancers, promoting cell growth and proliferation. Forkhead box containing…”
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