Search Results - "Pirskanen, A."

Characterization of a Common Susceptibility Locus for Asthma-Related Traits by Laitinen, Tarja, Polvi, Anne, Rydman, Pia, Vendelin, Johanna, Pulkkinen, Ville, Salmikangas, Paula, Mäkelä, Siru, Rehn, Marko, Pirskanen, Asta, Rautanen, Anna, Zucchelli, Marco, Gullstén, Harriet, Leino, Marina, Alenius, Harri, Petäys, Tuula, Haahtela, Tari, Laitinen, Annika, Laprise, Catherine, Hudson, Thomas J., Laitinen, Lauri A., Kere, Juha

“…Susceptibility to asthma depends on variation at an unknown number of genetic loci. To identify susceptibility genes on chromosome 7p, we adopted a…”
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Involvement of Proteasome in the Dynamic Assembly of the Androgen Receptor Transcription Complex by Kang, Zhigang, Pirskanen, Asta, Jänne, Olli A, Palvimo, Jorma J

“…We have used the chromatin immunoprecipitation technique to analyze the formation of the androgen receptor (AR) transcription complex onto prostate-specific…”
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Hormonal regulation of vitamin D receptor levels and osteocalcin synthesis in human osteosarcoma cells by MAENPAA, P, MAHONEN, A, PIRSKANEN, A

“…1,25(OH)2D3 was found to regulate its own receptor levels via an increase in corresponding mRNA levels in human osteoblast-like osteosarcoma cells (MG-63). In…”
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Biochemical indicators of bone formation in foals after transfer from pasture to stables for the winter months by Mäenpää, P E, Pirskanen, A, Koskinen, E

“…Serum alkaline phosphatase activity and serum concentrations of osteocalcin, free thyroxine, protein, and cholesterol were measured in 14 foals monthly from…”
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Characterization of GPRA, a Novel G Protein-Coupled Receptor Related to Asthma by Vendelin, Johanna, Pulkkinen, Ville, Rehn, Marko, Pirskanen, Asta, Raisanen-Sokolowski, Anne, Laitinen, Annika, Laitinen, Lauri A, Kere, Juha, Laitinen, Tarja

“…We recently identified a novel positional asthma susceptibility gene, GPRA, which belongs to the G protein-coupled receptor family. In the present studies, we…”
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Downstream target genes of the neuropeptide S–NPSR1 pathway by Vendelin, Johanna, Bruce, Sara, Holopainen, Päivi, Pulkkinen, Ville, Rytilä, Paula, Pirskanen, Asta, Rehn, Marko, Laitinen, Tarja, Laitinen, Lauri A., Haahtela, Tari, Saarialho-Kere, Ulpu, Laitinen, Annika, Kere, Juha

“…The neuropeptide S (NPS)–NPS receptor 1 (NPSR1) pathway has recently been implicated in the pathogenesis of asthma. The purpose of this study was to identify…”
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Characterization of three fragments that constitute the monomers of the human lysyl hydroxylase isoenzymes 1-3. The 30-kDa N-terminal fragment is not required for lysyl hydroxylase activity by Rautavuoma, Kati, Takaluoma, Kati, Passoja, Kaisa, Pirskanen, Asta, Kvist, Ari-Pekka, Kivirikko, Kari I, Myllyharju, Johanna

“…Lysyl hydroxylase (LH) catalyzes the formation of hydroxylysine in collagens; three human isoenzymes have been cloned so far. We report here on the…”
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Biochemical indicators related to antioxidant status and bone metabolic activity in Finnish elderly men by Mäenpää, P H, Pirhonen, A, Pirskanen, A, Pekkanen, J, Alfthan, G, Kivelä, S L, Nissinen, A

“…Serum concentrations of vitamins A, D and E, osteocalcin, calcium, selenium, cholesterol and HDL-cholesterol were measured in 270 elderly Finnish men aged from…”
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Noncovalent complex formation of tetratosylated resorcarene with aromatic, aliphatic, and cyclic alkyl ammonium ions: a mass spectrometric study of complex properties by Ventola, Elina, Pirskanen, Atte, Vainiotalo, Pirjo

“…The ability of tetratosylated resorcarene to form complexes with aromatic ammonium ions was investigated by electrospray ionization Fourier transform ion…”
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PAS4 ECONOMETRIC MODELING IN CHRONIC ASTHMA ALLOWS COMPARISONS BETWEEN DIFFERENT THERAPY GROUPS by Palmu, PJ, Reissell, E, Laitinen, T, Rehn, M, Pirskanen, A, Salonoja, M, Minkkinen, S, Kunnas, T

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PAS2 DRUG ADVERSE EVENTS MODIFYTHE TREATMENT AND COMPLIANCE OF ASTHMA PATIENTS by Laitinen, T, Reissell, E, Palmu, PJ, Rehn, M, Pirskanen, A, Salonoja, M, Minkkinen, S, Kunnas, T

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PAA18 DATA EXTRACTION METHODS, ECONOMETRIC MODELING AND FACTORIAL ANALYSIS REVEAL CLINICALLY IMPORTANT PATIENT PROFILES IN CHRONIC ASTHMA by Reissell, E, Palmu, PJ, Schultz, J, Pirskanen, A, Salonoja, M, Kunnas, T, Sintonen, H, Haahtela, T, Tukiainen, P, Lindqvist, A, Laitinen, T

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RS4 CLINICALLY IMPORTANT FACTORS CONTRIBUTING TO COSTS OF CARE DEFINED VIA ANALYSIS OF COMPREHSIVE PATIENT RECORDS by Palmu, PJ, Reissell, E, Schultz, J, Rehn, M, Pirskanen, A, Minkkinen, S, Salonoja, M, Kunnas, T, Sintonen, H, Haahtela, T, Lindqvist, A, Laitinen, T

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IGFs, insulin, Shh, bFGF, and TGF-beta1 interact synergistically to promote somite myogenesis in vitro by Pirskanen, A, Kiefer, J C, Hauschka, S D

“…Studies from our group and others have shown that in vitro somite myogenesis is regulated by neural tube and notochord factors including Wnt, Sonic hedgehog…”
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Identification of arginine-700 as the residue that binds the C-5 carboxyl group of 2-oxoglutarate in human lysyl hydroxylase 1 by Passoja, Kaisa, Myllyharju, Johanna, Pirskanen, Asta, Kivirikko, Kari I

“…Lysyl hydroxylase catalyzes the formation of hydroxylysine in collagens by a reaction that involves oxidative decarboxylation of 2-oxoglutarate. Its binding…”
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PAS6 CLINICAL OUTCOME OF CHRONIC ASTHMA by Reissell, E, Haukka, J, Minkkinen, S, Laitinen, T, Salonoja, M, Pirskanen, A, Palmu, P, Rehn, M, Honkanen, H, Lahtinen, T, Lindqvist, A, Kunnas, T

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Biochemical indicators of bone metabolic activity in bovine periparturient hypocalcemia by Lappeteläinen, R, Lappeteläinen, E, Hassinen, T, Hahl, M, Pirskanen, A, Mäenpää, P H

“…Twenty-one paretic and 30 nonparetic periparturient ambulatory cows were studied together with 13 non-pregnant control cows. Blood samples were collected…”
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Site-directed mutagenesis of human lysyl hydroxylase expressed in insect cells. Identification of histidine residues and an aspartic acid residue critical for catalytic activity by Pirskanen, A, Kaimio, A M, Myllylä, R, Kivirikko, K I

“…Lysyl hydroxylase (EC 1.14.11.4), an alpha 2 homodimer, catalyzes the formation of hydroxylysine in collagens. We expressed here human lysyl hydroxylase in…”
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Effects of transforming growth factor beta 1 on the regulation of osteocalcin synthesis in human MG-63 osteosarcoma cells by Pirskanen, A, Jääskeläinen, T, Mäenpää, P H

“…Treatment of human MG-63 osteosarcoma cells with human recombinant transforming growth factor beta 1 (TGF-beta 1) was found to inhibit cell proliferation. In…”
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Substrate specificity of human prolyl-4-hydroxylase by Tandon, Manish, Wu, Min, Begley, Tadhg P., Myllyharju, Johanna, Pirskanen, Asta, Kivirikko, Kari

“…Proline analogs (3-F, 3-Cl, 3-Br, 3,3-cyclopropyl, 3,3-methylene, 3-Me, and 4-Me) were synthesized, incorporated into CbzGlyPheXGlyOEt, and tested as substrate…”
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