Search Results - "Pirro, Matteo"
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Curcumin as a natural regulator of monocyte chemoattractant protein-1
Published in Cytokine & growth factor reviews (01-02-2017)“…Graphical abstract Effects of curcumin on MCP-1 levels in several in vitro , in vivo and clinical studies…”
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2
LDL-C: lower is better for longer-even at low risk
Published in BMC medicine (08-10-2020)“…Low-density lipoprotein cholesterol (LDL-C) causes atherosclerotic disease, as demonstrated in experimental and epidemiological cohorts, randomised controlled…”
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Effects of statins on the biological features of mesenchymal stem cells and therapeutic implications
Published in Heart failure reviews (01-09-2021)“…Statins are well-known lipid-lowering drugs. The pleiotropic effects of statins have brought about some beneficial effects on improving the therapeutic…”
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The regulation and importance of monocyte chemoattractant protein-1
Published in Current opinion in hematology (01-01-2018)“…PURPOSE OF REVIEWMonocyte chemoattractant protein (MCP)-1, a chemokine regulating monocyte chemotaxis and T-lymphocyte differentiation by binding to the CC…”
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The role of phosphatidylserine recognition receptors in multiple biological functions
Published in Cellular & molecular biology letters (26-03-2020)“…Apoptotic cells are rapidly engulfed and degraded by phagocytes through efferocytosis. Efferocytosis is a highly regulated process. It is triggered upon the…”
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CD47: role in the immune system and application to cancer therapy
Published in Cellular oncology (Dordrecht) (01-02-2020)“…Background CD47 is a widely expressed cellular receptor well known for its immunoregulatory functions. By interacting with its ligands, including…”
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Statins and the COVID-19 main protease: in silico evidence on direct interaction
Published in Archives of medical science (2020)“…No proven drug and no immunisation are yet available for COVID-19 disease. The SARS-CoV-2 main protease (Mpro), a key coronavirus enzyme, which is a potential…”
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Endothelial and cardiac progenitor cells for cardiovascular repair: A controversial paradigm in cell therapy
Published in Pharmacology & therapeutics (Oxford) (01-01-2018)“…Stem cells have the potential to differentiate into cardiovascular cell lineages and to stimulate tissue regeneration in a paracrine/autocrine manner; thus,…”
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Curcumin as a MicroRNA Regulator in Cancer: A Review
Published in Reviews of physiology, biochemistry and pharmacology (01-01-2016)“…Curcumin is a natural dietary polyphenol for which anti-tumor effects have been documented. Anti-inflammatory and antioxidant properties of curcumin, along…”
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Is There a Role for Curcumin Supplementation in the Treatment of Non-Alcoholic Fatty Liver Disease? The Data Suggest Yes
Published in Current pharmaceutical design (01-01-2017)“…Nonalcoholic fatty liver disease (NAFLD) is the most common type of liver disease. NAFLD is considered a multifactorial disease and a clinically relevant…”
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Effects of statins on mitochondrial pathways
Published in Journal of cachexia, sarcopenia and muscle (01-04-2021)“…Statins are a family of drugs that are used for treating hyperlipidaemia with a recognized capacity to prevent cardiovascular disease events. They inhibit…”
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PCSK9 and cancer: Rethinking the link
Published in Biomedicine & pharmacotherapy (01-08-2021)“…Cancer is emerging as a major problem globally, as it accounts for the second cause of death despite medical advances. According to epidemiological and basic…”
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The Role of Efferocytosis in Autoimmune Diseases
Published in Frontiers in immunology (20-07-2018)“…Apoptosis happens continuously for millions of cells along with the active removal of apoptotic debris in order to maintain tissue homeostasis. In this…”
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PCSK9 at the crossroad of cholesterol metabolism and immune function during infections
Published in Journal of cellular physiology (01-09-2017)“…Sepsis, a complex and dynamic syndrome resulting from microbial invasion and immune system dysregulation, is associated with an increased mortality, reaching…”
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The role of TFEB in tumor cell autophagy: Diagnostic and therapeutic opportunities
Published in Life sciences (1973) (01-03-2020)“…Autophagy is a conserved “self-eating” recycling process which removes aggregated or misfolded proteins, or defective organelles, to maintain cellular…”
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Emerging roles for high‐density lipoproteins in neurodegenerative disorders
Published in BioFactors (Oxford) (01-09-2019)“…Lipoproteins are the complexes of different lipids and proteins, which are devoted to the transport and clearance of lipids or lipid‐related molecules in the…”
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Regulatory effects of berberine on microRNome in Cancer and other conditions
Published in Critical reviews in oncology/hematology (01-08-2017)“…Abstract Berberine (BBR) is an isoquinoline alkaloid found in different plant families such as Berberidaceae, Ranunculaceae, and Papaveraceae. BBR is…”
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Impact of Bariatric Surgery on Pulse Wave Velocity as a Measure of Arterial Stiffness: a Systematic Review and Meta-analysis
Published in Obesity surgery (01-10-2021)“…Purpose Weight loss during post-bariatric surgery period has been linked to both reduced ASCVD mortality and overall mortality. Atherosclerosis causes arteries…”
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Lipoprotein(a) and inflammation: A dangerous duet leading to endothelial loss of integrity
Published in Pharmacological research (01-05-2017)“…[Display omitted] Lp(a), inflammation and endothelial injury. Lipoprotein(a) [Lp(a)] is an enigmatic lipoprotein whose ancestral useful properties have been…”
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PCSK9 and inflammation: a review of experimental and clinical evidence
Published in European heart journal. Cardiovascular pharmacotherapy (01-10-2019)“…Abstract Proprotein convertase subtilisin/kexin Type 9 (PCSK9) is now identified as an important and major player in hypercholesterolaemia and atherosclerosis…”
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