Search Results - "Pirotton, S."

Lolium perenne peptide immunotherapy is well tolerated and elicits a protective B‐cell response in seasonal allergic rhinitis patients by Mösges, R., Koch, A. F., Raskopf, E., Singh, J., Shah‐Hosseini, K., Astvatsatourov, A., Hauswald, B., Yarin, Y., Corazza, F., Haazen, L., Pirotton, S., Allekotte, S., Zadoyan, G., Legon, T., Durham, S. R., Shamji, M. H.

“…Background Systemic allergic reactions are a risk for allergen immunotherapy that utilizes intact allergen preparations. We evaluated the safety, efficacy and…”
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Short course of grass allergen peptides immunotherapy over 3 weeks reduces seasonal symptoms in allergic rhinoconjunctivitis with/without asthma: A randomized, multicenter, double‐blind, placebo‐controlled trial by Mösges, R., Bachert, C., Panzner, P., Calderon, M. A., Haazen, L., Pirotton, S., Wathelet, N., Durham, S. R., Bonny, M.‐A., Legon, T., von Frenckell, R., Pfaar, O., Shamji, M. H.

“…Background Immunotherapy with peptide hydrolysates from Lolium perenne (LPP) is an alternative treatment for seasonal allergic rhinitis with or without asthma…”
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A randomized, double‐blind, placebo‐controlled, dose‐finding trial with Lolium perenne peptide immunotherapy by Mösges, R., Kasche, E. M., Raskopf, E., Singh, J., Sohlich, L., Astvatsatourov, A., Shah‐Hosseini, K., Pirotton, S., Haazen, L., Durham, S. R., Legon, T., Zadoyan, G., Shamji, M. H.

“…Background A novel subcutaneous allergen immunotherapy formulation (gpASIT+™) containing Lolium perenne peptides (LPP) and having a short up‐dosing phase has…”
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Influence of DNA condensation state on transfection efficiency in DNA/polymer complexes: An AFM and DLS comparative study by Volcke, C., Pirotton, S., Grandfils, Ch, Humbert, C., Thiry, P.A., Ydens, I., Dubois, P., Raes, M.

“…Atomic force microscopy (AFM) is used to describe the formation process of polymer/DNA complexes. Two main objectives of this research are presented. The first…”
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Enhancement of transfection efficiency through rapid and noncovalent post-PEGylation of poly(dimethylaminoethyl methacrylate)/DNA complexes by Pirotton, Sabine, Muller, Caroline, Pantoustier, Nadège, Botteman, François, Collinet, Sébastien, Grandfils, Christian, Dandrifosse, Guy, Degée, Philippe, Dubois, Philippe, Raes, Martine

“…The aim of this work was to develop a new strategy to introduce poly(ethylene glycol) (PEG) into methacrylate-based polymer/ DNA complexes in order to produce…”
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Involvement of multiple receptors in the actions of extracellular ATP: the example of vascular endothelial cells by Motte, S., Communi, D., Pirotton, S., Boeynaems, J.-M.

“…The role of ATP and ADP as intercellular mediators is now well established. The presence of the nucleotides in extracellular fluids can result from several…”
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heterogeneity of ATP receptors in aortic endothelial cells : involvement of P2y and P2u receptors in inositol phosphate response by MOTTE, S, PIROTTON, S, BOEYNAEMS, J. M

“…Extracellular ATP plays an important role in the regulation of prostacyclin and nitric oxide release from vascular endothelial cells. These cellular responses…”
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Involvement of inositol 1,4,5-trisphosphate and calcium in the action of adenine nucleotides on aortic endothelial cells by Pirotton, S, Raspe, E, Demolle, D, Erneux, C, Boeynaems, J M

“…ADP and ATP, in the 1-100 microM range of concentrations, increased the formation of inositol phosphates in bovine aortic endothelial cells. The accumulation…”
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Immunologic mechanisms of a short-course of Lolium perenne peptide immunotherapy: A randomized, double-blind, placebo-controlled trial by Sharif, Hanisah, Singh, Iesha, Kouser, Lubna, Mösges, Ralph, Bonny, Marie-Alix, Karamani, Angeliki, Parkin, Rebecca V., Bovy, Nicolas, Kishore, Uday, Robb, Abigail, Katotomichelakis, Michael, Holtappels, Gabriële, Derycke, Lara, Corazza, Francis, von Frenckell, Rémy, Wathelet, Nathalie, Duchateau, Jean, Legon, Thierry, Pirotton, Sabine, Durham, Stephen R., Bachert, Claus, Shamji, Mohamed H.

“…A 3-week short-course of adjuvant-free hydrolysates of Lolium perenne peptide (LPP) immunotherapy for rhinoconjunctivitis with or without asthma over 4…”
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Lolium perenne peptides for treatment of grass pollen allergy: A randomized, double-blind, placebo-controlled clinical trial by Shamji, Mohamed H., Ceuppens, Jan, Bachert, Claus, Hellings, Peter, Placier, Gaël, Thirion, Gaëtan, Bovy, Nicolas, Durham, Stephen R., Duchateau, Jean, Legon, Thierry, Pirotton, Sabine

“…Because of the extensive cross-reactivity of allergenic components of grass pollen from different species, the L perenne allergen can be used to treat allergic…”
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Evidence that a form of ATP uncomplexed with divalent cations is the ligand of P2y and nucleotide/P2u receptors on aortic endothelial cells by Motte, S., Pirotton, S., Boeynaems, J.M.

“…1 The response of bovine aortic endothelial cells to adenosine 5′‐triphosphate (ATP) is mediated by both P2y and nucleotide/P2u receptors. In order to…”
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Ecto-phosphorylation on aortic endothelial cells. Exquisite sensitivity to staurosporine by Pirotton, S, Boutherin-Falson, O, Robaye, B, Boeynaems, J M

“…One- and two-dimensional gel electrophoresis of proteins from bovine aortic endothelial cells (BAEC) incubated with [gamma-32P]ATP revealed the preferential…”
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Pharmacological characterization of the human P2Y4 receptor by COMMUNI, D, MOTTE, S, BOEYNAEMS, J.-M, PIROTTON, S

“…The P2Y4 receptor is a new member of the P2Y family which functionally behaves as a pyrimidinergic receptor. The pharmacological properties of the human P2Y4…”
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Dual role of GTP-binding proteins in the control of endothelial prostacyclin by Pirotton, S, Erneux, C, Boeynaems, J M

“…Pretreatment of bovine aortic endothelial cells with pertussis toxin inhibited partially the accumulation of inositol phosphates in response to ATP, whereas…”
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Metabolism of inositol phosphates in ATP-stimulated vascular endothelial cells by PIROTTON, S, VERJANS, B, BOEYNAEMS, J.-M, ERNEUX, C

“…The accumulation of InsP1, InsP2, InsP3 and InsP4 isomers was investigated in bovine aortic endothelial cells labelled with [3H]inositol and stimulated with…”
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Cloning and Functional Expression of a Human Uridine Nucleotide Receptor (∗) by Communi, Didier, Pirotton, Sabine, Parmentier, Marc, Boeynaems, Jean-Marie

“…In order to isolate new subtypes of P2 purinoceptors, sets of degenerate oligonucleotide primers were synthesized on the basis of the best conserved segments…”
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Pharmacological characterization of the human P 2Y4 receptor by Communi, Didier, Motte, Serge, Boeynaems, Jean-Marie, Pirotton, Sabine

“…The P2Y 4 receptor is a new member of the P2Y family which functionally behaves as a pyrimidinergic receptor. The pharmacological properties of the human P2Y 4…”
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Endothelial P2-purinoceptors: subtypes and signal transduction by Pirotton, S, Communi, D, Motte, S, Janssens, R, Boeynaems, J M

“…1. Adenine nucleotides stimulate the synthesis and release of prostacyclin and nitric oxide (two potent platelet aggregation inhibitors) by endothelial cells…”
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P2-purinergic receptors in vascular endothelial cells: from concept to reality by Boeynaems, J M, Pirotton, S, Van Coevorden, A, Raspe, E, Demolle, D, Erneux, C

“…ATP exerts at least 2 actions on arterial endothelial cells: it stimulates the release of endothelium-derived relaxing factor, a still unidentified…”
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Control of prostacyclin production by vascular cells: role of adenine nucleotides and serotonin by Boeynaems, J M, Demolle, D, Pirotton, S, Raspe, E, Lecomte, M, Hepburn, A, Van Coevorden, A, Erneux, C

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