Search Results - "Pirot, Nelly"

The multifunctional protein E4F1 links P53 to lipid metabolism in adipocytes by Lacroix, Matthieu, Linares, Laetitia K., Rueda-Rincon, Natalia, Bloch, Katarzyna, Di Michele, Michela, De Blasio, Carlo, Fau, Caroline, Gayte, Laurie, Blanchet, Emilie, Mairal, Aline, Derua, Rita, Cardona, Fernando, Beuzelin, Diane, Annicotte, Jean-Sebastien, Pirot, Nelly, Torro, Adeline, Tinahones, Francisco J., Bernex, Florence, Bertrand-Michel, Justine, Langin, Dominique, Fajas, Lluis, Swinnen, Johannes V., Le Cam, Laurent

“…Growing evidence supports the importance of the p53 tumor suppressor in metabolism but the mechanisms underlying p53-mediated control of metabolism remain…”
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Antifibrotic, Antioxidant, and Immunomodulatory Effects of Mesenchymal Stem Cells in HOCl‐Induced Systemic Sclerosis by Maria, Alexandre T. J., Toupet, Karine, Bony, Claire, Pirot, Nelly, Vozenin, Marie‐Catherine, Petit, Benoît, Roger, Pascal, Batteux, Frédéric, Le Quellec, Alain, Jorgensen, Christian, Noël, Danièle, Guilpain, Philippe

“…Objective Systemic sclerosis (SSc) is a rare intractable disease with unmet medical need and fibrosis‐related mortality. Absence of efficient treatments has…”
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Three-dimensional imaging of vascular development in the mouse epididymis by Damon-Soubeyrand, Christelle, Bongiovanni, Antonino, Chorfa, Areski, Goubely, Chantal, Pirot, Nelly, Pardanaud, Luc, Piboin-Fragner, Laurence, Vachias, Caroline, Bravard, Stephanie, Guiton, Rachel, Thomas, Jean-Leon, Saez, Fabrice, Kocer, Ayhan, Tardivel, Meryem, Drevet, Joël R, Henry-Berger, Joelle

“…Long considered an accessory tubule of the male reproductive system, the epididymis is proving to be a key determinant of male fertility. In addition to its…”
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Zika Virus Infection Promotes Local Inflammation, Cell Adhesion Molecule Upregulation, and Leukocyte Recruitment at the Blood-Brain Barrier by Clé, Marion, Desmetz, Caroline, Barthelemy, Jonathan, Martin, Marie-France, Constant, Orianne, Maarifi, Ghizlane, Foulongne, Vincent, Bolloré, Karine, Glasson, Yaël, De Bock, Frédéric, Blaquiere, Marine, Dehouck, Lucie, Pirot, Nelly, Tuaillon, Edouard, Nisole, Sébastien, Najioullah, Fatiha, Van de Perre, Philippe, Cabié, André, Marchi, Nicola, Gosselet, Fabien, Simonin, Yannick, Salinas, Sara

“…Zika virus (ZIKV) can be associated with neurological impairment in children and adults. To reach the central nervous system, viruses have to cross the…”
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Notch inhibition overcomes resistance to tyrosine kinase inhibitors in EGFR-driven lung adenocarcinoma by Bousquet Mur, Emilie, Bernardo, Sara, Papon, Laura, Mancini, Maicol, Fabbrizio, Eric, Goussard, Marion, Ferrer, Irene, Giry, Anais, Quantin, Xavier, Pujol, Jean-Louis, Calvayrac, Olivier, Moll, Herwig P, Glasson, Yaël, Pirot, Nelly, Turtoi, Andrei, Cañamero, Marta, Wong, Kwok-Kin, Yarden, Yosef, Casanova, Emilio, Soria, Jean-Charles, Colinge, Jacques, Siebel, Christian W, Mazieres, Julien, Favre, Gilles, Paz-Ares, Luis, Maraver, Antonio

“…EGFR-mutated lung adenocarcinoma patients treated with gefitinib and osimertinib show a therapeutic benefit limited by the appearance of secondary mutations,…”
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Long‐Term Detection of Human Adipose‐Derived Mesenchymal Stem Cells After Intraarticular Injection in SCID Mice by Toupet, Karine, Maumus, Marie, Peyrafitte, Julie‐Anne, Bourin, Philippe, Lent, Peter L. E. M., Ferreira, Rosanna, Orsetti, Béatrice, Pirot, Nelly, Casteilla, Louis, Jorgensen, Christian, Noël, Danièle

“…Objective Mesenchymal stem cells (MSCs) represent a promising tool for cell therapy for several disorders, among them the osteoarticular diseases. For such…”
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The mouse HP1 proteins are essential for preventing liver tumorigenesis by Saksouk, Nehmé, Hajdari, Shefqet, Perez, Yannick, Pratlong, Marine, Barrachina, Célia, Graber, Céline, Grégoire, Damien, Zavoriti, Aliki, Sarrazin, Amélie, Pirot, Nelly, Noël, Jean-Yohan, Khellaf, Lakhdar, Fabbrizio, Eric, Julien, Eric, Cammas, Florence M.

“…Chromatin organization is essential for appropriate interpretation of the genetic information. Here, we demonstrated that the chromatin-associated proteins HP1…”
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BAT3 modulates p300-dependent acetylation of p53 and autophagy-related protein 7 (ATG7) during autophagy by Sebti, Salwa, Prébois, Christine, Pérez-Gracia, Esther, Bauvy, Chantal, Desmots, Fabienne, Pirot, Nelly, Gongora, Céline, Bach, Anne-Sophie, Hubberstey, Andrew V., Palissot, Valérie, Berchem, Guy, Codogno, Patrice, Linares, Laetitia K., Liaudet-Coopman, Emmanuelle, Pattingre, Sophie

“…Autophagy is regulated by posttranslational modifications, including acetylation. Here we show that HLA-B—associated transcript 3 (BAT3) is essential for basal…”
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A 31-plex panel for high-dimensional single-cell analysis of murine preclinical models of solid tumors by imaging mass cytometry by Glasson, Yaël, Chépeaux, Laure-Agnès, Dumé, Anne-Sophie, Jay, Philippe, Pirot, Nelly, Bonnefoy, Nathalie, Michaud, Henri-Alexandre

“…Currently, the study of resistance mechanisms and disease progression in cancer relies on the capacity to analyze tumors as a complex ecosystem of healthy and…”
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Histology of Tritia mutabilis gonads: using reproductive biology to support sustainable fishery management by Mallet Alicia, Jouvenel Jean-Yves, Broyon Morgane, Pirot Nelly, Geffroy Benjamin

“…The mutable nassa, Tritia mutabilis, a marine gastropod that is widely exploited on the Adriatic coast is an important source of income for small-scale…”
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RIP140 regulates transcription factor HES1 oscillatory expression and mitogenic activity in colon cancer cells by Sfeir, Nour, Kajdan, Marilyn, Jalaguier, Stéphan, Bonnet, Sandrine, Teyssier, Catherine, Pyrdziak, Samuel, Yuan, Rong, Bousquet, Emilie, Maraver, Antonio, Bernex, Florence, Pirot, Nelly, Boissière‐Michot, Florence, Castet‐Nicolas, Audrey, Lapierre, Marion, Cavaillès, Vincent

“…The transcription factor receptor‐interacting protein 140 (RIP140) regulates intestinal homeostasis and tumorigenesis through Wnt signaling. In this study, we…”
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Study of Usutu virus neuropathogenicity in mice and human cellular models by Clé, Marion, Barthelemy, Jonathan, Desmetz, Caroline, Foulongne, Vincent, Lapeyre, Lina, Bolloré, Karine, Tuaillon, Edouard, Erkilic, Nejla, Kalatzis, Vasiliki, Lecollinet, Sylvie, Beck, Cécile, Pirot, Nelly, Glasson, Yaël, Gosselet, Fabien, Alvarez Martinez, Maria Teresa, Van de Perre, Philippe, Salinas, Sara, Simonin, Yannick

“…Usutu virus (USUV), an African mosquito-borne flavivirus closely related to West Nile virus, was first isolated in South Africa in 1959. USUV emerged in Europe…”
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Design and selection of optimal ErbB-targeting bispecific antibodies in pancreatic cancer by Rabia, Emilia, Garambois, Véronique, Dhommée, Christine, Larbouret, Christel, Lajoie, Laurie, Buscail, Yoan, Jimenez-Dominguez, Gabriel, Choblet-Thery, Sylvie, Liaudet-Coopman, Emmanuelle, Cerutti, Martine, Jarlier, Marta, Ravel, Patrice, Gros, Laurent, Pirot, Nelly, Thibault, Gilles, Zhukovsky, Eugene A, Gérard, Pierre-Emmanuel, Pèlegrin, André, Colinge, Jacques, Chardès, Thierry

“…The ErbB family of receptor tyrosine kinases is a primary target for small molecules and antibodies for pancreatic cancer treatment. Nonetheless, the current…”
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Diversity and Evolution of Mineralized Skeletal Tissues in Chondrichthyans by Berio, Fidji, Broyon, Morgane, Enault, Sébastien, Pirot, Nelly, López-Romero, Faviel A., Debiais-Thibaud, Mélanie

“…The diversity of skeletal tissues in extant vertebrates includes mineralized and unmineralized structures made of bone, cartilage, or tissues of intermediate…”
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Anti-tumoral activity of the Pan-HER (Sym013) antibody mixture in gemcitabine-resistant pancreatic cancer models by Rabia, Emilia, Garambois, Véronique, Hubert, Julie, Bruciamacchie, Marine, Pirot, Nelly, Delpech, Hélène, Broyon, Morgane, Theillet, Charles, Colombo, Pierre-Emmanuel, Vie, Nadia, Tosi, Diego, Gongora, Celine, Khellaf, Lakhdar, Jarlier, Marta, Radosevic-Robin, Nina, Chardès, Thierry, Pèlegrin, André, Larbouret, Christel

“…Chemoresistance, particularly to gemcitabine, is a major challenge in pancreatic cancer. The epidermal growth factor receptor (EGFR) and human epidermal growth…”
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Description of the unusual digestive tract of Platax orbicularis and the potential impact of Tenacibaculum maritimum infection by Alix, Maud, Gasset, Eric, Bardon-Albaret, Agnes, Noel, Jean, Pirot, Nelly, Perez, Valérie, Coves, Denis, Saulnier, Denis, Lignot, Jehan-Hervé, Cucchi, Patricia N

“…Ephippidae fish are characterized by a discoid shape with a very small visceral cavity. Among them has a high economic potential due to its flesh quality and…”
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Lung endothelial barrier disruption in Lyl1-deficient mice by Pirot, Nelly, Delpech, Hélène, Deleuze, Virginie, Dohet, Christiane, Courtade-Saïdi, Monique, Basset-Léobon, Céline, Chalhoub, Elias, Mathieu, Danièle, Pinet, Valérie

“…Maturation of newly formed vessels is a multistep phenomenon during which functional endothelial barriers are established. Disruption of vessel integrity is an…”
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Sphingosine kinase-1 is central to androgen-regulated prostate cancer growth and survival by Dayon, Audrey, Brizuela, Leyre, Martin, Claire, Mazerolles, Catherine, Pirot, Nelly, Doumerc, Nicolas, Nogueira, Leonor, Golzio, Muriel, Teissié, Justin, Serre, Guy, Rischmann, Pascal, Malavaud, Bernard, Cuvillier, Olivier

“…Sphingosine kinase-1 (SphK1) is an oncogenic lipid kinase notably involved in response to anticancer therapies in prostate cancer. Androgens regulate prostate…”
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LYL1 activity is required for the maturation of newly formed blood vessels in adulthood by Pirot, Nelly, Deleuze, Virginie, El-Hajj, Rawan, Dohet, Christiane, Sablitzky, Fred, Couttet, Philippe, Mathieu, Danièle, Pinet, Valérie

“…The 2 related basic helix loop helix genes, LYL1 and TAL-1 are active in hematopoietic and endothelial lineages. While Tal-1 is essential for both…”
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Identification of monoclonal antibodies from naive antibody phage-display libraries for protein detection in formalin-fixed paraffin-embedded tissues by Mairaville, Célestine, Broyon, Morgane, Maurel, Margaux, Chentouf, Myriam, Chiavarina, Barbara, Turtoi, Andrei, Pirot, Nelly, Martineau, Pierre

“…Most antibodies used in immunohistochemistry (IHC) have been developed by animal immunization. We wanted to explore naive antibody repertoires displayed on…”
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