Search Results - "Piroli, Maria"
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Matrix Stiffness Modulates Mesenchymal Stem Cell Sensitivity to Geometric Asymmetry Signals
Published in Annals of biomedical engineering (01-06-2018)“…Human stem cells hold significant potential for the treatment of various diseases. However, their use as a therapy is hampered because of limited understanding…”
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Journal Article -
2
Polarity as a physiological modulator of cell function
Published in Frontiers in bioscience (01-01-2019)“…Cell polarity, the asymmetric distribution of proteins, organelles, and cytoskeleton, plays an important role in development, homeostasis, and disease…”
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Journal Article -
3
Deconstructing the Effects of Matrix Elasticity and Geometry in Mesenchymal Stem Cell Lineage Commitment
Published in Advanced functional materials (23-04-2014)“…A wide variety of environmental factors including physical and biochemical signals are responsible for stem cell behavior and function. In particular, matrix…”
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Journal Article -
4
Reducing brain kynurenic acid synthesis precludes kynurenine-induced sleep disturbances
Published in Journal of sleep research (01-05-2024)“…Patients with neurocognitive disorders often battle sleep disturbances. Kynurenic acid is a tryptophan metabolite of the kynurenine pathway implicated in the…”
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Journal Article -
5
Development of a bioreactor for in-vitro compression cycling of tissue engineered meniscal implants
Published in HardwareX (01-06-2023)“…[Display omitted] Injuries to the meniscus are common and can impair physical activities. Bioprinted meniscal tissue offers an attractive alternative to donor…”
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Journal Article -
6
Compression cycling of 3D-printed meniscal tissues in vitro using a custom bioreactor
Published in Bioprinting (Amsterdam, Netherlands) (01-07-2024)“…An estimated 750,000 arthroscopic knee operations are performed in the United States each year, and many are due to a torn meniscus. Transplantation with donor…”
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Journal Article -
7
3D printing a universal knee meniscus using a custom collagen ink
Published in Bioprinting (Amsterdam, Netherlands) (01-06-2023)“…Tears of the meniscus are among the most commonly diagnosed knee injuries. Because most of the meniscus lacks the ability to self-heal due to its low…”
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Journal Article -
8
Matrix Stiffness Modulates Mesenchymal Stem Cell Sensitivity to Geometric Asymmetry Signals
Published 01-01-2018“…Human stem cells hold significant potential for the treatment of various diseases. However, their use as a therapy is hampered by the limited understanding of…”
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Dissertation