Search Results - "Pirnik, D"

The effect of space flight on the production of actinomycin D by Streptomyces plicatus by LAM, K. S, GUSTAVSON, D. R, PIRNIK, D. L, PACK, E, BULANHAGUI, C, MAMBER, S. W, FORENZA, S, STODIECK, L. S, KLAUS, D. M

“…The effect of space flight on production of the antibiotic actinomycin D by Streptomyces plicatus WC56452 was examined onboard the US Space Shuttle mission…”
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Fusaricide, a New Cytotoxic N-Hydroxypyridone from Fusarium sp by McBrien, Kimberly D, Gao, Qi, Huang, Stella, Klohr, Steven E, Wang, Richard R, Pirnik, Dolores M, Neddermann, Kim M, Bursuker, Isia, Kadow, Kathleen F, Leet, John E

“…A new cytotoxic N-hydroxypyridone, fusaricide (1), was isolated from a Fusarium sp. Its structure was solved by X-ray diffraction and spectroscopic analyses…”
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Glucolipsin A and B, two new glucokinase activators produced by Streptomyces purpurogeniscleroticus and Nocardia vaccinii by Qian-Cutrone, J, Ueki, T, Huang, S, Mookhtiar, K A, Ezekiel, R, Kalinowski, S S, Brown, K S, Golik, J, Lowe, S, Pirnik, D M, Hugill, R, Veitch, J A, Klohr, S E, Whitney, J L, Manly, S P

“…During the screening of the natural products for their ability to increase the activity of glucokinase by relieving inhibition by long chain fatty acyl CoA…”
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Eupenifeldin, a novel cytotoxic bistropolone from Eupenicillium brefeldianum by Mayerl, F, Gao, Q, Huang, S, Klohr, S E, Matson, J A, Gustavson, D R, Pirnik, D M, Berry, R L, Fairchild, C, Rose, W C

“…Eupenifeldin was isolated from cultures of Eupenicillium brefeldianum ATCC 74184 by extraction and crystallization. The compound was identified as a…”
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10'-Desmethoxystreptonigrin, a novel analog of streptonigrin by Liu, W C, Barbacid, M, Bulgar, M, Clark, J M, Crosswell, A R, Dean, L, Doyle, T W, Fernandes, P B, Huang, S, Manne, V

“…10'-Desmethoxystreptonigrin, a novel analog of streptonigrin produced by Streptomyces albus, was discovered in a screen for inhibitors of farnesylation of RAS…”
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BMS-192548, a tetracyclic binding inhibitor of neuropeptide Y receptors, from Aspergillus niger WB2346. I. Taxonomy, fermentation, isolation and biological activity by Kodukula, K, Arcuri, M, Cutrone, J Q, Hugill, R M, Lowe, S E, Pirnik, D M, Shu, Y Z, Fernandes, P B, Seethala, R

“…During the screening of microbial fermentation extracts for their ability to inhibit the binding of 125I-peptid YY (PYY) to the neuropeptide Y (NPY) receptor…”
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Manumycins E, F and G, new members of manumycin class antibiotics, from Streptomyces sp by Shu, Y Z, Huang, S, Wang, R R, Lam, K S, Klohr, S E, Volk, K J, Pirnik, D M, Wells, J S, Fernandes, P B, Patel, P S

“…Three new manumycin class antibiotics, namely manumycins E, F and G, were isolated from the culture broth of Streptomyces sp. strain WB-8376. Their structures…”
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BMS-182123, a fungal metabolite that inhibits the production of TNF-alpha by macrophages and monocytes by Warr, G A, Veitch, J A, Walsh, A W, Hesler, G A, Pirnik, D M, Leet, J E, Lin, P F, Medina, I A, McBrien, K D, Forenza, S, Clark, J M, Lam, K S

“…A fungal metabolite, BMS-182123, which inhibited bacterial endotoxin-induced production of tumor necrosis factor (TNF-alpha) in murine macrophages and human…”
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Harziphilone and fleephilone, two new HIV REV/RRE binding inhibitors produced by Trichoderma harzianum by Qian-Cutrone, J, Huang, S, Chang, L P, Pirnik, D M, Klohr, S E, Dalterio, R A, Hugill, R, Lowe, S, Alam, M, Kadow, K F

“…During the screening of the natural products for their ability to inhibit the binding of REV (regulation of virion expression) protein to [33P] labeled RRE…”
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Haloemodins, a new class of endothelin-1 type B (ETB) receptor binding inhibitors by Shu, Y Z, Arcuri, M, Kozlowski, M R, Wang, R R, Lam, K S, Chang, L P, Pirnik, D M, Rose, P M

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Bacillaene, a novel inhibitor of procaryotic protein synthesis produced by Bacillus subtilis: production, taxonomy, isolation, physico-chemical characterization and biological activity by Patel, P S, Huang, S, Fisher, S, Pirnik, D, Aklonis, C, Dean, L, Meyers, E, Fernandes, P, Mayerl, F

“…Bacillaene, a novel polyene antibiotic, was discovered and isolated from fermentation broths of a strain of Bacillus subtilis. The novel antibiotic has a…”
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1-Methoxy-agroclavine from Penicillium sp. WC75209, a novel inhibitor of the Lck tyrosine kinase by Padmanabha, Ramesh, Shu, Yue-Zhong, Cook, Lynda S, Veitch, Judy A, Donovan, Marcella, Lowe, Susan, Huang, Stella, Pirnik, Dolores, Manly, Susan P

“…A high-throughput screen was developed and implemented to identify inhibitors of the Lck tyrosine kinase. This report describes the identification of a…”
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Ascosteroside, a new antifungal agent from Ascotricha amphitricha. I. Taxonomy, fermentation and biological activities by Gorman, J A, Chang, L P, Clark, J, Gustavson, D R, Lam, K S, Mamber, S W, Pirnik, D, Ricca, C, Fernandes, P B, O'Sullivan, J

“…Ascosteroside, a novel antifungal compound, was isolated from the culture broth of Ascotricha amphitricha. This compound is an alpha-linked glycoside of a…”
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Orevactaene, 1 a novel binding inhibitor of HIV-1 rev protein to Rev response element (RRE) from Epicoccum nigrum WC47880 by Shu, Yue-Zhong, Ye, Qingmei, Li, Hui, Kadow, Kathleen F., Hussain, Raouf A., Huang, Stella, Gustavson, Donald R., Lowe, Susan E., Chang, Li-Ping, Pirnik, Dolores M., Kodukula, Krishna

“…Orevactaene ( 1), a novel oxopolyene, was isolated from Epicoccum nigrum WC47880 during the screening of microbial fermentation extracts for their ability to…”
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