Search Results - "Pirnia, F"

Mitomycin C induces apoptosis and caspase-8 and -9 processing through a caspase-3 and Fas-independent pathway by Pirnia, F, Schneider, E, Betticher, D C, Borner, M M

“…Caspase-3 activity has been described to be essential for drug-induced apoptosis. Recent results suggest that in addition to its downstream executor function,…”
Get full text

Human delta Np73 regulates a dominant negative feedback loop for TAp73 and p53 by Grob, T J, Novak, U, Maisse, C, Barcaroli, D, Lüthi, A U, Pirnia, F, Hügli, B, Graber, H U, De Laurenzi, V, Fey, M F, Melino, G, Tobler, A

“…Inactivation of the tumour suppressor p53 is the most common defect in cancer cells. p53 is a sequence specific transcription factor that is activated in…”
Get full text

Cyclin D1 Overexpression in Bronchial Epithelia of Patients With Lung Cancer Is Associated With Smoking and Predicts Survival by Ratschiller, D, Heighway, J, Gugger, M, Kappeler, A, Pirnia, F, Schmid, R A, Borner, M M, Betticher, D C

“…Cyclin D1 is overexpressed in almost 60% of resectable non-small-cell lung cancer (NSCLC). In the absence of cyclin D1 gene amplification, overexpression is…”
Get full text

Terminal Neuroendocrine Differentiation of Human Prostate Carcinoma Cells in Response to Increased Intracellular Cyclic AMP by Y.-J. Bang, Pirnia, F., W.-G. Fang, Kang, W. K., Sartor, O., Whitesell, L., Ha, M. J., Tsokos, M., Sheahan, M. D., Nguyen, P., Niklinski, W. T., Myers, C. E., Trepel, J. B.

“…Recent clinicopathologic studies have shown that many prostatic adenocarcinomas express focal neuroendocrine differentiation and that neuroendocrine…”
Get full text

Uncertain Identity of Doxorubicin-Resistant MCF-7 Cell Lines Expressing Mutated p53 by Pirnia, Farzaneh, Breuleux, Madlaina, Schneider, Erasmus, Hochmeister, Manfred, Bates, Susan E., Marti, Andreas, Hotz, Michel A., Betticher, Daniel C., Borner, Markus M.

“…Another cell line (MCF-7 TH) has been independently selected by doxorubicin treatment at the National Cancer Institute (NCI) and demonstrated some of the same,…”
Get full text

P2-purinergic receptor agonists inhibit the growth of androgen-independent prostate carcinoma cells by WEI-GANG FANG, PIRNIA, F, YUNG-JUE BANG, MYERS, C. E, TREPEL, J. B

“…To develop a new approach to the treatment of advanced, hormone-refractory prostate cancer, the signal transductions regulating the growth of human…”
Get full text

PG490-mediated sensitization of lung cancer cells to Apo2L TRAIL-induced apoptosis requires activation of ERK2 by FRESE, Steffen, PIRNIA, Farzaneh, MIESCHER, Daniela, KRAJEWSKI, Stan, BORNER, Markus M, REED, John C, SCHMID, Ralph A

“…Tumor necrosis factor-related apoptosis-inducing ligand (Apo2L/TRAIL) belongs to the family of programmed cell death-inducing cytokines. Apo2L/TRAIL induces…”
Get full text

Alternative Splicing of the Human Cyclin D-binding Myb-like Protein (hDMP1) Yields a Truncated Protein Isoform That Alters Macrophage Differentiation Patterns by Tschan, Mario P., Fischer, Kimberlee M., Fung, Vivian S., Pirnia, Farzaneh, Borner, Markus M., Fey, Martin F., Tobler, Andreas, Torbett, Bruce E.

“…We have cloned two novel, alternatively spliced messages of human cyclin D-binding Myb-like protein (hDMP1). The known, full-length protein has been named…”
Get full text

RESPONSE: Multidrug-Resistant MCF-7 Cells: An Identity Crisis? by Pirnia, Farzaneh, Borner, Markus M.

Get full text

Inhibition of the 3-hydroxy-3-methylglutaryl-coenzyme A reductase pathway induces p53-independent transcriptional regulation of p21(WAF1/CIP1) in human prostate carcinoma cells by Lee, S J, Ha, M J, Lee, J, Nguyen, P, Choi, Y H, Pirnia, F, Kang, W K, Wang, X F, Kim, S J, Trepel, J B

“…Progression through the cell cycle is controlled by the induction of cyclins and the activation of cognate cyclin-dependent kinases. The…”
Get full text

Cyclin dl overexpression in bronchial epithelia of patients with lung cancer is associated with smoking and predicts survival by RATSCHILLER, D, HEIGHWAY, J, GUGGER, M, KAPPELER, A, PIRNIA, F, SCHMID, R. A, BORNER, M. M, BETTICHER, D. C

Get full text

Lovastatin induces apoptosis in a primitive neuroectodermal tumor cell line in association with RB down-regulation and loss of the G1 checkpoint by KIM, Jung-Sik, PIRNIA, Farzaneh, MUSHINSKI, J. Frederic, TREPEL, Jane B, YUNG HYUN CHOI, NGUYEN, Phuongmai, KNEPPER, Benjamin, TSOKOS, Maria, SCHULTE, Theodor W, BIRRER, Michael J, BLAGOSKLONNY, Mikhail V, SCHAEFER, Olaf

“…To develop a new approach to the treatment of primitive neuroectodermal tumors we evaluated the effect of the HMG-CoA reductase inhibitor lovastatin on the…”
Get full text

Human [Delta]Np73 regulates a dominant negative feedback loop for TAp73 and p53 by Grob, T J, Novak, U, Maisse, C, Barcaroli, D, Lüthi, A U, Pirnia, F, Hügli, B, Graber, H U, De Laurenzi, V, Fey, M F, Melino, G, Tobler, A

“…Inactivation of the tumour suppressor p53 is the most common defect in cancer cells. p53 is a sequence specific transcription factor that is activated in…”
Get full text

The detergent Triton X-100 induces a death pattern in human carcinoma cell lines that resembles cytotoxic lymphocyte-induced apoptosis by Borner, Markus M., Schneider, Erasmus, Pirnia, Farzaneh, Sartor, Oliver, Trepel, Jane B., Myers, Charles E.

“…The detergent Triton X-100 (TX100) was used with the intention to establish a model for necrotic cell death. However TX100 was found to induce apoptotic and…”
Get full text

Inhibition of the 3-hydroxy-3-methylglutaryl-coenzyme A reductase pathway induces p53-independent transcriptional regulation of p21 super(WAF1/CIP1) in human prostate carcinoma cells by Lee, Su Jae, Ha, Mahn Joon, Lee, Jeen, Nguyen, PhuongMai, Choi, Yung Hyun, Pirnia, F, Kang, Won-Ki, Wang, Xiao-Fan, Kim, Seong-Jin, Trepel, J B

“…Progression through the cell cycle is controlled by the induction of cyclins and the activation of cognate cyclin-dependent kinases. The…”
Get full text

Novel proteomics approach for functional identification of regulators of cancer drug response and apoptosis in ex vivo tissue cultures of human colorectal cancer by Borner, M. M., Pirnia Borner, F., Betticher, D. C., Gloor, B.

“…Abstract only…”
Get full text

P sub(2)-purinergic receptor agonists inhibit the growth of androgen-independent prostate carcinoma cells by Fang, Wei-Gang, Pirnia, F, Bang, Yung-Jue, Myers, CE, Trepel, J B

“…To develop a new approach to the treatment of advanced, hormone-refractory prostate cancer, the signal transductions regulating the growth of human…”
Get full text

Cytotoxicity and metabolism of 4-methoxy-8-(beta-D-ribofuranosylamino)pyrimido[5,4-d]pyrimidine in HCT 116 colon cancer cells by Grem, J L, Daychild, P, Drake, J, Geoffroy, F, Trepel, J B, Pirnia, F, Allegra, C J

“…We examined the cytotoxicity, biochemical effects and metabolism of 4-methoxy-8-(beta-D-ribofuranosylamino)pyrimido[5,4-d]pyrimidine (MRPP), a synthetic…”
Get more information