Search Results - "Pirnay, S."

Allergens grouping names on packaging: Are the substances similar enough to ensure safety? The worst case scenarios question this by Vandamme, C, Guillaume, M, Pirnay, S

“…European Commission Regulation (EU) n°2023/1545 introduced the concept of grouping names in the cosmetics sector in July 2023. These groups bring together…”
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Intravenous buprenorphine and norbuprenorphine pharmacokinetics in humans by Huestis, M.A, Cone, E.J, Pirnay, S.O, Umbricht, A, Preston, K.L

“…Abstract Background Prescribed sublingual (SL) buprenorphine is sometimes diverted for intravenous (IV) abuse, but no human pharmacokinetic data are available…”
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Optimization of the method of the content‐containing interaction evaluation for cosmetic products by gas chromatography–mass spectrometry by Charron, C., De Vaugelade, S., Richard, F., Largitte, A., Pirnay, S.

“…In July 2013, the European Regulation (EC) No 1223/2009 came into effect in order to secure cosmetic products. The content‐containing interaction between the…”
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A critical review of the causes of death among post-mortem toxicological investigations: analysis of 34 buprenorphine-associated and 35 methadone-associated deaths by Pirnay, S., Borron, S. W., Giudicelli, C. P., Tourneau, J., Baud, F. J., Ricordel, I.

“…ABSTRACT Aims  To assess the trends in the number, mortality and the nature of forensic cases involving toxicological detection of buprenorphine or methadone…”
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Evaluation of the content - containing interaction in cosmetic products using gas chromatography-mass spectrometry by Thomas, C., Siong, D., Pirnay, S.

“…Synopsis Objective Since the publication of the Regulation (EC) No 1223/2009 on cosmetic products, the content‐containing interaction between the packaging and…”
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Determination of the influence of factors (ethanol, pH and aw) on the preservation of cosmetics using experimental design by Berthele, H., Sella, O., Lavarde, M., Mielcarek, C., Pense-Lheritier, A.-M., Pirnay, S.

“…Synopsis Objective Ethanol, pH and water activity are three well‐known parameters that can influence the preservation of cosmetic products. With the new…”
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Comparison of the compact dry TC method with the standard method ISO 21149:2006 for determining aerobic colony counts in cosmetic emulsion by De Vaugelade, S., Aime, M., Farcette, N., Maurel, E., Lacour, T., Thomas, C., Bouchonnet, S., Pirnay, S.

“…Objective Compact Dry TC, a rapid method kit for determining aerobic colony counts, has been developed by Nissui Pharmaceutical Co. for food application. These…”
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Predictive microbiology for cosmetics based on physicals, chemicals and concentration parameters by Ghalleb, S., De Vaugelade, S., Sella, O., Lavarde, M., Mielcarek, C., Pense-Lheritier, A.-M., Pirnay, S.

“…Synopsis Objective Challenge test (CT) is essential to assure the efficiency of the preservative system in products. A previous study realized by our staff in…”
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Sensitive method for the detection of 22 benzodiazepines by gas chromatography–ion trap tandem mass spectrometry by Pirnay, Stephane, Ricordel, Ivan, Libong, Danielle, Bouchonnet, Stéphane

“…A gas chromatography–ion trap tandem mass spectrometry method for simultaneous detection of 22 benzodiazepines is presented. Four operating modes were first…”
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Buprenorphine is protective against the depressive effects of norbuprenorphine on ventilation by Mégarbane, Bruno, Marie, Nicolas, Pirnay, Stéphane, Borron, Stephen W., Gueye, Papa N., Risède, Patricia, Monier, Claire, Noble, Florence, Baud, Frédéric J.

“…High dose buprenorphine is used as substitution treatment in heroin addiction. However, deaths have been reported in addicts using buprenorphine. The role of…”
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Liquid chromatographic–electrospray ionization mass spectrometric quantitative analysis of buprenorphine, norbuprenorphine, nordiazepam and oxazepam in rat plasma by Pirnay, Stephane, Hervé, Françoise, Bouchonnet, Stéphane, Perrin, Bérengère, Baud, Frédéric J., Ricordel, Ivan

“…A liquid chromatographic–mass spectrometric method with electrospray ionization is presented for the simultaneous determination of buprenorphine, nordiazepam…”
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Development and validation of a gas chromatography–mass spectrometry method for the simultaneous determination of buprenorphine, flunitrazepam and their metabolites in rat plasma: application to the pharmacokinetic study by Pirnay, Stephane, Bouchonnet, Stephane, Hervé, Françoise, Libong, Danielle, Milan, Nathalie, d’Athis, Philippe, Baud, Frédéric, Ricordel, Ivan

“…Buprenorphine (BUP), a synthetic opioid analgesic, is frequently abused alone, and in association with benzodiazepines. Fatalities involving buprenorphine…”
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Smoking ban in a psychiatry department: Are nonsmoking employees less exposed to environmental tobacco smoke? by Vorspan, F, Bloch, V, Guillem, E, Dupuy, G, Pirnay, S, Jacob, N, Lépine, J.-P

“…Abstract Staff members of psychiatric facilities are at high risk of secondhand smoking. Smoking exposure was assessed in 41 nonsmoking employees of a…”
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Selection and Optimization of Hydrolysis Conditions for the Quantification of Urinary Metabolites of MDMA by Pirnay, Stephane O., Abraham, Tsadik T., Lowe, Ross H., Huestis, Marilyn A.

“…Recovery of 3,4-methylenedioxymethamphetamine (MDMA) urinary metabolites requires optimization of the hydrolysis of 4-hydroxy-3-methyoxymethamphetamine (HMMA),…”
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Flunitrazepam does not alter cerebral distribution of buprenorphine in the rat by Megarbane, Bruno, Pirnay, Stéphane, Borron, Stephen W., Trout, Hervé, Monier, Claire, Risède, Patricia, Boschi, Gabrielle, Baud, Frédéric J.

“…Deaths have been reported among heroin addicts related to combined buprenorphine and flunitrazepam use. The aim of this study was to determine the existence of…”
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Urinary MDMA, MDA, HMMA, and HMA Excretion Following Controlled MDMA Administration to Humans by Abraham, Tsadik T., Barnes, Allan J., Lowe, Ross H., Kolbrich Spargo, Erin A., Milman, Garry, Pirnay, Stephane O., Gorelick, David A., Goodwin, Robert S., Huestis, Marilyn A.

“…3,4-Methylenedioxymethamphetamine (MDMA), or ecstasy, is excreted as unchanged drug, 3,4-methylenedioxyamphetamine (MDA), and free and glucuronidated/sulfated…”
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Dexamethasone hepatic induction in rats subsequently treated with high dose buprenorphine does not lead to respiratory depression by Hreiche, Raymond, Mégarbane, Bruno, Pirnay, Stéphane, Borron, Stephen W., Monier, Claire, Risède, Patricia, Milan, Nathalie, Descatoire, Véronique, Pessayre, Dominique, Baud, Frédéric J.

“…In humans, asphyxic deaths and severe poisonings have been attributed to high-dosage buprenorphine, a maintenance therapy for heroin addiction. However, in…”
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Adsorption–desorption effects in ion trap mass spectrometry using in situ ionization by Libong, Danielle, Pirnay, Stéphane, Bruneau, Cyrille, Rogalewicz, Françoise, Ricordel, Ivan, Bouchonnet, Stéphane

“…Quadrupole mass spectrometers were compared for the GC–MS analysis of six molecules frequently encountered in analytical toxicology: diazepam, alprazolam,…”
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Determination of significant factors in order to assess the stability of cosmetic products in regards with the use/or not of challenge tests by Lafosse, S., Pirnay, S.

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Interaction of drugs of abuse and maintenance treatments with human P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) by Tournier, Nicolas, Chevillard, Lucie, Megarbane, Bruno, Pirnay, Stéphane, Scherrmann, Jean-Michel, Declèves, Xavier

“…Drug interaction with P-glycoprotein (P-gp) and breast cancer resistance protein (BCRP) may influence its tissue disposition including blood–brain barrier…”
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