Retinol status and associated factors in mother–newborn pairs

Retinol status and associated factors in mother–newborn pairs

Background Vitamin A deficiency is still considered to be a nutritional problem during pregnancy, lactation and early childhood. The present study aimed to assess the vitamin A status of women and their newborns in the Brazilian Northeast and to determine the association between retinol in the mater...

Full description

Saved in:
Bibliographic Details
Published in:Journal of human nutrition and dietetics Vol. 33; no. 2; pp. 222 - 231
Main Authors: Bezerra, D.S., Ribeiro, K.D.S., Lima, M.S.R., Pires Medeiros, J.F., Silva, A.G.C.L., Dimenstein, R., Osório, M.M.
Format: Journal Article
Language:English
Published: England Blackwell Publishing Ltd 01-04-2020
Subjects:
Blood
Children
Colostrum
Confidence intervals
Cord blood
Health risk assessment
high‐performance liquid chromatography
Infants
Lactation
Liquid chromatography
Mothers
Neonates
Nutrient deficiency
Pregnancy
Prenatal development
Regression analysis
Retinene
serum
Statistical analysis
Umbilical cord
Vitamin A
high-performance liquid chromatography
vitamin A
serum
umbilical cord
colostrum
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Background Vitamin A deficiency is still considered to be a nutritional problem during pregnancy, lactation and early childhood. The present study aimed to assess the vitamin A status of women and their newborns in the Brazilian Northeast and to determine the association between retinol in the maternal serum, umbilical cord blood and colostrum. Methods Vitamin A status in 65 pairs of women and newborns was assessed from samples of the mother’s serum, umbilical cord serum and colostrum using high‐performance liquid chromatography. The inadequacy of the vitamin A status of mothers and infants was identified if the retinol values were <0.7 µmol L−1 in maternal serum or umbilical cord blood or <1.05 µmol L−1 in colostrum. Results The prevalence of inadequate maternal vitamin A status was 21.5% (95% CI: 11.5%–31.5%) and 13.8% [95% confidence interval (CI) = 5.4%–22.2%] based on maternal serum and colostrum, respectively. Among newborns, 41.5% (95% CI = 29.3%–53.5%) presented a low status of vitamin A based on cord serum. Multiple linear regression analysis identified that maternal serum retinol is a predictor of umbilical cord retinol (P = 0.005). Retinol in maternal serum was lower in mothers who were less educated (P = 0.04) and colostrum retinol was higher in older (P = 0.04) and multiparous (P = 0.002) mothers. Conclusions Vitamin A deficiency is a common problem among mothers attended in public hospitals in Northeast Brazil and maternal retinol concentrations are associated with retinol status in newborns. Maternal age, parity and educational level were related to the maternal vitamin A status.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0952-3871
1365-277X
DOI:10.1111/jhn.12707