Search Results - "Pires, I."

Anticancer Properties of Essential Oils and Other Natural Products by Cabral, C., Lemos, M. F. L., Magalhães, M., Blowman, K., Pires, I. M.

“…Essential oils are secondary metabolites with a key-role in plants protection, consisting primarily of terpenes with a volatile nature and a diverse array of…”
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Regulation of autophagy by ATF4 in response to severe hypoxia by Rzymski, T, Milani, M, Pike, L, Buffa, F, Mellor, H R, Winchester, L, Pires, I, Hammond, E, Ragoussis, I, Harris, A L

“…Activating transcription factor 4 (ATF4) is a transcription factor induced under severe hypoxia and a component of the PERK pathway involved in the unfolded…”
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Atrial matrix remodeling in atrial fibrillation patients with aortic stenosis by Fragão-Marques, Mariana, Miranda, I, Martins, D, Barroso, I, Mendes, C, Pereira-Neves, A, Falcão-Pires, I, Leite-Moreira, A

“…This study aimed to evaluate atrium extracellular matrix remodeling in atrial fibrillation (AF) patients with severe aortic stenosis, through histological…”
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Animal models of heart failure with preserved ejection fraction by Conceição, G., Heinonen, I., Lourenço, A. P., Duncker, D. J., Falcão-Pires, I.

“…Heart failure with preserved ejection fraction (HFpEF) constitutes a clinical syndrome in which the diagnostic criteria of heart failure are not accompanied by…”
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Targeting radiation-resistant hypoxic tumour cells through ATR inhibition by Pires, I M, Olcina, M M, Anbalagan, S, Pollard, J R, Reaper, P M, Charlton, P A, McKenna, W G, Hammond, E M

“…Background: Most solid tumours contain regions of sub-optimal oxygen concentration (hypoxia). Hypoxic cancer cells are more resistant to radiotherapy and…”
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A multi-tier study on supply chain flexibility in the automotive industry by Thomé, Antonio Márcio T., Scavarda, Luiz Felipe, Pires, Sílvio R.I., Ceryno, Paula, Klingebiel, Katja

“…Over the past two decades, the scope of some key subjects in operations management has extended beyond the single company to include supply chain (SC) partners…”
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Apocynin influence on oxidative stress and cardiac remodeling of spontaneously hypertensive rats with diabetes mellitus by Rosa, C M, Gimenes, R, Campos, D H S, Guirado, G N, Gimenes, C, Fernandes, A A H, Cicogna, A C, Queiroz, R M, Falcão-Pires, I, Miranda-Silva, D, Rodrigues, P, Laurindo, F R, Fernandes, D C, Correa, C R, Okoshi, M P, Okoshi, K

“…Although increased oxidative stress is a major component of diabetic hypertensive cardiomyopathy, research into the effects of antioxidants on cardiac…”
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Rodent models of heart failure: an updated review by Gomes, A. C., Falcão-Pires, I., Pires, A. L., Brás-Silva, C., Leite-Moreira, A. F.

“…Heart failure (HF) is one of the major health and economic burdens worldwide, and its prevalence is continuously increasing. The study of HF requires reliable…”
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Ki-67 and PCNA Expression in Canine Mammary Tumors and Adjacent Nonneoplastic Mammary Glands: Prognostic Impact by a Multivariate Survival Analysis by Carvalho, M. I., Pires, I., Prada, J., Lobo, L., Queiroga, F. L.

“…The assessment of tumor proliferation has been considered a determining prognostic factor in canine mammary tumors (CMTs). However, no studies have assessed…”
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Secondary emissions during fiber laser cutting of nuclear material by Lopez, A., Assunção, E., Pires, I., Quintino, L.

“…The laser process has been studied for dismantling work for more than 10years, however there is almost no data available concerning secondary emissions…”
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Impact of postmenopausal vaginal discomfort on sex and relationships in Brazil: the CLOSER survey by Pompei, L. M., Wender, M. C. O., Kulak, J., Pires, I., Suvarna, Y., Nappi, R. E.

“…The CLOSER (CLarifying Vaginal Atrophy's Impact On SEx and Relationships) survey investigated how postmenopausal vaginal atrophy (VA) affects relationships…”
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Worse cardiac remodeling in response to pressure overload in type 2 diabetes mellitus by Gonçalves, N, Gomes-Ferreira, C, Moura, C, Roncon-Albuquerque, R, Leite-Moreira, A.F, Falcão-Pires, I

“…Abstract Background Diabetic cardiomyopathy is characterized by cardiac structural and functional abnormalities. Additionally, chronic pressure overload…”
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Synergistic impact of endurance training and intermittent hypobaric hypoxia on cardiac function and mitochondrial energetic and signaling by Magalhães, J, Falcão-Pires, I, Gonçalves, I.O, Lumini-Oliveira, J, Marques-Aleixo, I, dos Passos, E, Rocha-Rodrigues, S, Machado, N.G, Moreira, A.C, Miranda-Silva, D, Moura, C, Leite-Moreira, A.F, Oliveira, P.J, Torrella, J.R, Ascensão, A

“…Abstract Background Intermittent hypobaric-hypoxia (IHH) and endurance-training (ET) are cardioprotective strategies against stress-stimuli. Mitochondrial…”
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Residual stresses in 18CrNiMo7-6 linear friction welded high strength steel chains by Nunes, D. G., Effertz, P. S., Quintino, L., Pires, I., Fuchs, F., Enzinger, N.

“…Linear friction welding is a solid-state process that comprises rapid heating and cooling of the welded parts. Residual stresses (RS) as in every other welding…”
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Electives in the medical curriculum - an opportunity to achieve students' satisfaction? by Ramalho, Ana Rita, Vieira-Marques, P M, Magalhães-Alves, C, Severo, M, Ferreira, M A, Falcão-Pires, I

“…Electives are perceived by medical students as a valuable, highly regarded experience, allowing them to customize learning experiences and enabling them to…”
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High COX‐2 expression is associated with increased angiogenesis, proliferation and tumoural inflammatory infiltrate in canine malignant mammary tumours: a multivariate survival study by Carvalho, M. I., Pires, I., Prada, J., Raposo, T. P., Gregório, H., Lobo, L., Queiroga, F. L.

“…COX‐2 expression affects mammary tumourigenesis by promoting angiogenesis and cell proliferation, encouraging metastatic spread and tumour‐associated…”
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Parameter and Deposition Strategy Analysis for WAAM Processing of AISI 410 Stainless Steel by Pires, I., Assunção, E. G., Florescu, M. C., Savu, I. D., Criveanu, M. C., Klobčar, K.

“…Wire + Arc Additive Manufacturing (WAAM®) is an additive manufacturing (AM) process capable of producing near net shape parts while reducing costs and thus…”
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PARAMETER AND DEPOSITION STRATEGY ANALYSIS FOR WAAM PROCESSING OF AISI 410 by Pires, I, Assuncao, E G, Florescu, M C, Savu, I D, Criveanu, M C, Klobcar, D

“…Wire + Arc Additive Mani,facturing (WAAMM is an additive mant,facturing (AM process capable of producing near net shape parts while reducing costs and thus…”
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Oxaliplatin responses in colorectal cancer cells are modulated by CHK2 kinase inhibitors by Pires, IM, Ward, TH, Dive, C

“…Background and purpose:  Checkpoint kinase 2 (CHK2) is activated by DNA damage and can contribute to p53 stabilization, modulating growth arrest and/or…”
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High COX‐2 expression in canine mast cell tumours is associated with proliferation, angiogenesis and decreased overall survival by Gregório, H., Raposo, T., Queiroga, F. L., Pires, I., Pena, L., Prada, J.

“…COX‐2 overexpression is associated with several hallmarks of carcinogenesis such as proliferation, angiogenesis, invasion and metastasis. Fifty cases of canine…”
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