Search Results - "Pires, Diana"

Phage Therapy: Going Temperate? by Monteiro, Rodrigo, Pires, Diana Priscila, Costa, Ana Rita, Azeredo, Joana

“…Strictly lytic phages have been consensually preferred for phage therapy purposes. In contrast, temperate phages have been avoided due to an inherent capacity…”
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Current challenges and future opportunities of phage therapy by Pires, Diana P, Costa, Ana Rita, Pinto, Graça, Meneses, Luciana, Azeredo, Joana

“…ABSTRACT Antibiotic resistance is a major public health challenge worldwide, whose implications for global health might be devastating if novel antibacterial…”
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Phage therapy: a step forward in the treatment of Pseudomonas aeruginosa infections by Pires, Diana, Boas, Diana Patrícia Andrade Vilas, Sillankorva, Sanna, Azeredo, Joana

“…Antimicrobial resistance constitutes one of the major worldwide public health concerns. Bacteria are becoming resistant to the vast majority of antibiotics and…”
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Genetically Engineered Phages: a Review of Advances over the Last Decade by Pires, Diana P, Cleto, Sara, Sillankorva, Sanna, Azeredo, Joana, Lu, Timothy K

“…Soon after their discovery in the early 20th century, bacteriophages were recognized to have great potential as antimicrobial agents, a potential that has yet…”
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Bacteriophage-encoded depolymerases: their diversity and biotechnological applications by Pires, Diana P, Oliveira, Hugo, Melo, Luís D. R, Sillankorva, Sanna, Azeredo, Joana

“…Bacteriophages (phages), natural enemies of bacteria, can encode enzymes able to degrade polymeric substances. These substances can be found in the bacterial…”
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Phage therapy efficacy: a review of the last 10 years of preclinical studies by Melo, Luís D R, Oliveira, Hugo, Pires, Diana P, Dabrowska, Krystyna, Azeredo, Joana

“…Due to the rise of multidrug-resistant infections in humans, phage therapy is gaining renewed attention in Western medicine. Despite the increasing number of…”
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Designing P. aeruginosa synthetic phages with reduced genomes by Pires, Diana P., Monteiro, Rodrigo, Mil-Homens, Dalila, Fialho, Arsénio, Lu, Timothy K., Azeredo, Joana

“…In the era where antibiotic resistance is considered one of the major worldwide concerns, bacteriophages have emerged as a promising therapeutic approach to…”
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An overview of the current state of phage therapy for the treatment of biofilm-related infections by Pires, Diana P, Meneses, Luciana, Brandão, Ana C, Azeredo, Joana

“…Bacterial biofilms are involved in many chronic and difficult-to-treat infections. Phage therapy against infectious biofilms is becoming a promising strategy,…”
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Differential transcription profiling of the phage LUZ19 infection process in different growth media by Brandão, Ana, Pires, Diana P., Coppens, Lucas, Voet, Marleen, Lavigne, Rob, Azeredo, Joana

“…RNA sequencing of phage-infected bacterial cultures offers a snapshot of transcriptional events occurring during the infection process, providing insights into…”
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Impact of phage predation on P. aeruginosa adhered to human airway epithelium: major transcriptomic changes in metabolism and virulence-associated genes by Brandão, Ana C., Putzeys, Leena, Pires, Diana P., Voet, Marleen, Paeshuyse, Jan, Azeredo, Joana, Lavigne, Rob

“…Phage therapy is a promising adjunct therapeutic approach against bacterial multidrug-resistant infections, including Pseudomonas aeruginosa-derived…”
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Understanding the Complex Phage-Host Interactions in Biofilm Communities by Pires, Diana P, Melo, Luís D.R, Azeredo, Joana

“…Bacteriophages and bacterial biofilms are widely present in natural environments, a fact that has accelerated the evolution of phages and their bacterial hosts…”
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A systematic review of the use of bacteriophages for in vitro biofilm control by Meneses, Luciana, Brandão, Ana Catarina, Coenye, Tom, Braga, Ana Cristina, Pires, Diana Priscila, Azeredo, Joana

“…Bacteriophages (phages) are very promising biological agents for the prevention and control of bacterial biofilms. However, little is known about the…”
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Use of newly isolated phages for control of Pseudomonas aeruginosa PAO1 and ATCC 10145 biofilms by Pires, Diana, Sillankorva, Sanna, Faustino, Alberta, Azeredo, Joana

“…Pseudomonas aeruginosa is a relevant opportunistic pathogen involved in nosocomial infections that frequently shows low antibiotic susceptibility. One of its…”
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Exploring the transcriptional landscape of phage–host interactions using novel high-throughput approaches by Putzeys, Leena, Wicke, Laura, Brandão, Ana, Boon, Maarten, Pires, Diana P, Azeredo, Joana, Vogel, Jörg, Lavigne, Rob, Gerovac, Milan

“…In the last decade, powerful high-throughput sequencing approaches have emerged to analyse microbial transcriptomes at a global scale. However, to date,…”
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CkP1 bacteriophage, a S16-like myovirus that recognizes Citrobacter koseri lipopolysaccharide through its long tail fibers by Oliveira, Hugo, Santos, Sílvio, Pires, Diana P., Boeckaerts, Dimitri, Pinto, Graça, Domingues, Rita, Otero, Jennifer, Briers, Yves, Lavigne, Rob, Schmelcher, Mathias, Dötsch, Andreas, Azeredo, Joana

“…Citrobacter koseri is an emerging Gram-negative bacterial pathogen, which causes urinary tract infections. We isolated and characterized a novel S16-like…”
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Screening and in silico characterization of prophages in Helicobacter pylori clinical strains by Ferreira, Rute, Pinto, Graça, Presa, Eva, Oleastro, Mónica, Silva, Catarina, Vieira, Luís, Sousa, Cláudia, Pires, Diana P., Figueiredo, Ceu, Melo, Luís D.R.

“…The increase of antibiotic resistance calls for alternatives to control Helicobacter pylori, a Gram-negative bacterium associated with various gastric…”
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A genotypic analysis of five P. aeruginosa strains after biofilm infection by phages targeting different cell surface receptors by Pires, Diana P., Dötsch, Andreas, Anderson, Erin M., Hao, Youai, Khursigara, Cezar M., Lam, J. S., Sillankorva, Sanna, Azeredo, Joana

“…The Supplementary Material for this article can be found online at: http://journal.frontiersin.org/article/10.3389/fmicb…”
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In Vitro Activity of Bacteriophages Against Planktonic and Biofilm Populations Assessed by Flow Cytometry by Pires, Diana P, Melo, Luís D R

“…The in vitro activity of bacteriophages against planktonic cultures and biofilms is commonly evaluated by culture methods. However, these methods can lead to…”
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Phage-Host Interaction Analysis by Flow Cytometry Allows for Rapid and Efficient Screening of Phages by Melo, Luís D R, Monteiro, Rodrigo, Pires, Diana P, Azeredo, Joana

“…Recently, phages have become popular as an alternative to antibiotics. This increased demand for phage therapy needs rapid and efficient methods to screen…”
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Exploitation of a Klebsiella Bacteriophage Receptor-Binding Protein as a Superior Biorecognition Molecule by Nogueira, Catarina L, Pires, Diana P, Monteiro, Rodrigo, Santos, Sílvio B, Carvalho, Carla M

“…Klebsiella pneumoniae is a Gram-negative bacterium that has become one of the leading causes of life-threatening healthcare-associated infections (HAIs),…”
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