Search Results - "Piraino, Susan"
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The impact of minimally oversized adeno-associated viral vectors encoding human factor VIII on vector potency in vivo
Published in Molecular therapy. Methods & clinical development (01-01-2016)“…Recombinant adeno-associated viral (rAAV) vectors containing oversized genomes provide transgene expression despite low efficiency packaging of complete…”
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Overexpression of cystatin C in synovium does not reduce synovitis or cartilage degradation in established osteoarthritis
Published in Arthritis research & therapy (16-01-2015)“…Cathepsin K (catK) expression is increased in cartilage, bone and synovium during osteoarthritis (OA). To study the role of catK expression and elevated…”
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STR/ort Mice, a Model for Spontaneous Osteoarthritis, Exhibit Elevated Levels of Both Local and Systemic Inflammatory Markers
Published in Comparative medicine (01-08-2011)“…Osteoarthritis is a common joint disease that currently lacks disease-modifying treatments. Development of therapeutic agents for osteoarthritis requires…”
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247. Characterization of Oversized rAAV Vectors for Human FVIII Gene Transfer
Published in Molecular therapy (01-05-2015)Get full text
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Characteristics of Minimally Oversized Adeno-Associated Virus Vectors Encoding Human Factor VIII Generated Using Producer Cell Lines and Triple Transfection
Published in Human gene therapy. Part B. Methods (01-02-2017)“…Several ongoing clinical studies are evaluating recombinant adeno-associated virus (rAAV) vectors as gene delivery vehicles for a variety of diseases. However,…”
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Induction of antitumor immunity with dendritic cells transduced with adenovirus vector-encoding endogenous tumor-associated antigens
Published in The Journal of immunology (1950) (15-07-1999)“…Dendritic cells (DCs) are professional Ag-presenting cells that are being considered as potential immunotherapeutic agents to promote host immune responses…”
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Analysis of recombinant adeno-associated virus packaging and requirements for rep and cap gene products
Published in Journal of Virology (01-03-1997)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Immunogene Therapy for Murine Melanoma Using Recombinant Adenoviral Vectors Expressing Melanoma-Associated Antigens
Published in Molecular therapy (01-03-2000)“…Adenoviral vectors expressing tumor-associated antigens can be used to evoke a specific immune response and inhibit tumor growth. In this study, we tested the…”
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