Search Results - "Piraino, Anthony J."

Uricosuric effect of CGS-12970, a new thromboxane synthase inhibitor by Saris, S D, Piraino, A J, Morgan, J M, Hirschhorn, W L, Meidl, E, Schaffer, A V

“…3-Methyl-2-(3-pyridyl)-1-indoleoctanoic acid (CGS-12970) is a reversible thromboxane synthase inhibitor that was noted to lower serum uric acid during…”
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Effect of renal impairment on the pharmacokinetics and pharmacodynamics of desirudin by Lefèvre, Gilbert, Duval, Martine, Gauron, Sonia, Brookman, Laurence J., Rolan, Paul E., Morris, Thomas M., Piraino, Anthony J., Morgan, John M., Palmisano, Maria, Close, Philippe

“…Objective To investigate the pharmacokinetics and pharmacodynamics of desirudin in subjects with various degrees of renal impairment in comparison with…”
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Comparative pharmacokinetics and bioavailability of nitroglycerin and its metabolites from Transderm-Nitro, Nitrodisc, and Nitro-Dur II systems using a stable-isotope technique by Sun, J X, Piraino, A J, Morgan, J M, Joshi, J C, Cipriano, A, Chan, K, Redalieu, E

“…The pharmacokinetics and bioavailability of nitroglycerin (GTN) and its metabolites, 1,2-glyceryl dinitrate (1,2-GDN) and 1,3-glyceryl dinitrate (1,3-GDN),…”
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Managing medication in the elderly by Piraino, A J

“…The elderly receive 30% of all prescriptions and buy 40% of all OTC drugs. In addition to the potential pitfalls inherent to age-related changes in…”
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Pharmacokinetic disposition of multiple-dose transdermal nicotine in healthy adult smokers by KOCHNAK, G. M, SUN, J. X, CHOI, R. L, PIRAINO, A. J

“…The pharmacokinetics and cardiovascular effects of nicotine and its major metabolite, cotinine, were characterized during repeated once-daily application for 5…”
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Pharmacokinetics of multiple daily transdermal doses of nicotine in healthy smokers by ROSS, H. D, CHAN, K. K. H, PIRAINO, A. J, JOHN, V. A

“…The plasma concentration-time profiles and pharmacokinetics were characterized for nicotine and its major metabolite, cotinine, after multiple daily…”
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Blockbuster buster by Piraino, A J

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The uncontrollable epidemic of 2010? by Piraino, A J

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Inhibition of angiotensin-converting enzyme with libenzapril in normotensive males by Morgan, J M, Piraino, A J, Saris, S D, Graham, C S, Hirschhorn, W L, Kochak, G M, Choi, R L

“…The effect of intravenous (i.v.) libenzapril was studied in six healthy males by administering i.v. angiotensin I (AI) administered in stepwise increments of…”
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Hypoglycemic and insulin response to a continuous intravenous infusion of CGP-35126 recombinant human insulin-like growth factor-I (rhIGF-I) in healthy males by Morgan, J M, Saris, S D, Capuzzi, D M, Good, W R, John, V A, Guler, H P, Seaman, J, Piraino, A J

“…Recombinant human insulin-like growth factor-I (rhIGF-I) produced by expression in a yeast vector was evaluated in seven normal men to determine effects on…”
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Diazepam concentrations in parotid saliva, mixed saliva, and plasma by DiGregorio, G J, Piraino, A J, Ruch, E

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Prolonged Hyperalimentation in Catabolic Chronic Dialysis Therapy Patients by Piraino, Anthony J., Firpo, John J., Powers, Donald V.

“…Plasma concentrations of 25 essential (EAA) and nonessential (NEAA) amino acids were measured pre- and postdialysis in 46 chronic hemodialysis therapy (CDT)…”
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5-Fluorouracil concentrations in rat plasma, parotid saliva, and bile and protein binding in rat plasma by Celio, L A, DiGregorio, G J, Ruch, E, Pace, J N, Piraino, A J

“…The pharmacokinetics of 5-fluorouracil were studied over a 60-min period in rats that received 12.5, 25.0, and 50.0 mg/kg iv. The plasma concentration-time…”
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Detection and quantitation of phencyclidine in rat parotid saliva and plasma by Digregorio, G J, Ruch, E, Piraino, A J

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Correlations of parotid saliva and plasma lidocaine concentrations in rats by DiGregorio, G J, Piraino, A J, Ruch, E

“…The concentration ratios of parotid saliva to plasma lidocaine were determined in rats after a single dose (10 mg of lidocaine/kg) and constant infusion (60…”
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Investigation of digoxin, quinidine, and disopyramide interactions in rats utilizing parotid saliva, blood, and other tissues by DiGregorio, G J, Piraino, A J, Ruch, E K, Basseches, P J

“…Blood, parotid saliva, heart, liver, and kidney concentrations of digoxin and quinidine were determined in rats chronically treated with digoxin and in…”
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Excretion of barbiturates into induced parotid saliva of the rat by Piraino, A J, Digregorio, G J, Nagle, B T

“…On the basis of the results presented in this study, it has been shown that the five barbiturates studied are excreted into the parotid saliva of the rat…”
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Radioimmunoassay of methadone in rat parotid saliva by Digregorio, G J, Piraino, A J, Ruch, E K

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Secretion of drugs by the parotid glands of rats and human beings by Di Gregorio, G J, Piraino, A J, Nagle, B T, Knaiz, E K

“…The following drugs have been demonstrated to be secreted by the parotid glands of rats and human beings: amobarbital, chlorpromazine, codeine, glutethimide,…”
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A small animal model utilizing salivary drug excretion for pharmacokinetic determinations by Piraino, A J, DiGregorio, G J, Ruch, E K

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