Search Results - "Piquard, Francois"

Effect of interval versus continuous training on cardiorespiratory and mitochondrial functions: relationship to aerobic performance improvements in sedentary subjects by Daussin, Frédéric N, Zoll, Joffrey, Dufour, Stéphane P, Ponsot, Elodie, Lonsdorfer-Wolf, Evelyne, Doutreleau, Stéphane, Mettauer, Bertrand, Piquard, François, Geny, Bernard, Richard, Ruddy

“…The goal of the study was to determine the effects of continuous (CT) vs. intermittent (IT) training yielding identical mechanical work and training duration…”
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Impact of iron oxide nanoparticles on brain, heart, lung, liver and kidneys mitochondrial respiratory chain complexes activities and coupling by Baratli, Yosra, Charles, Anne-Laure, Wolff, Valérie, Ben Tahar, Lotfi, Smiri, Leila, Bouitbir, Jamal, Zoll, Joffrey, Piquard, François, Tebourbi, Olfa, Sakly, Mohsen, Abdelmelek, Hafedh, Geny, Bernard

“…•Iron nanoparticles are widely used in all life domains but might be toxic.•Despite its importance, mitochondrial toxicity is poorly known.•Brain, heart, lung,…”
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Training at high exercise intensity promotes qualitative adaptations of mitochondrial function in human skeletal muscle by Daussin, Frederic N, Zoll, Joffrey, Ponsot, Elodie, Dufour, Stephane P, Doutreleau, Stephane, Lonsdorfer, Evelyne, Ventura-Clapier, Renee, Mettauer, Bertrand, Piquard, Francois, Geny, Bernard, Richard, Ruddy

“…1 Physiology and Functional Explorations Department, Centre Hospitalier Régional Universitaire of Strasbourg, Strasbourg; 2 Physiology Department, Faculty of…”
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Ischemic preconditioning specifically restores complexes I and II activities of the mitochondrial respiratory chain in ischemic skeletal muscle by Thaveau, Fabien, MD, MSc, Zoll, Joffrey, PhD, Rouyer, Olivier, MD, Chafke, Nabil, MD, PhD, Kretz, Jean Georges, MD, Piquard, Francois, PhD, Geny, Bernard, MD, PhD

“…Objective Defective mitochondrial function has been reported in patients presenting with peripheral arterial disease, suggesting it might be an important…”
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Effects of a High Fat Meal Associated with Water, Juice, or Champagne Consumption on Endothelial Function and Markers of Oxidative Stress and Inflammation in Young, Healthy Subjects by Rouyer, Olivier, Auger, Cyril, Charles, Anne-Laure, Talha, Samy, Meyer, Alain, Piquard, Francois, Andres, Emmanuel, Schini-Kerth, Valerie, Geny, Bernard

“…Endothelial dysfunction (ED), often linked to hypertriglyceridemia, is an early step of atherosclerosis. We investigated, in a randomized cross-over study,…”
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Dysregulation of pulsatility in aging IV. Pulsatile signaling and cardiovascular aging: functions and regulation of natriuretic peptide signaling by Charloux, Anne, Brandenberger, Gabrielle, Piquard, François, Geny, Bernard

“…Atrial and brain natriuretic peptides (ANP and BNP) are cardiac hormones connecting heart and kidney and playing a key role in hydromineral and hemodynamic…”
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Reductive stress impairs myoblasts mitochondrial function and triggers mitochondrial hormesis by Singh, François, Charles, Anne-Laure, Schlagowski, Anna-Isabel, Bouitbir, Jamal, Bonifacio, Annalisa, Piquard, François, Krähenbühl, Stephan, Geny, Bernard, Zoll, Joffrey

“…Even though oxidative stress damage from excessive production of ROS is a well known phenomenon, the impact of reductive stress remains poorly understood. This…”
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Contralateral Leg as a Control During Skeletal Muscle Ischemia-Reperfusion by Thaveau, Fabien, M.D., M.Sc, Zoll, Joffrey, Ph.D, Bouitbir, Jamal, Ph.D, Ribera, Florence, Ph.D, Di Marco, Paola, M.D, Chakfe, Nabil, M.D., Ph.D, Kretz, Jean Georges, M.D, Piquard, Francois, Ph.D, Geny, Bernard, M.D., Ph.D

“…Background Recent data demonstrated that hind limb ischemia induces skeletal muscle mitochondrial dysfunctions. Improvement of such metabolic myopathy improves…”
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Brain natriuretic peptide and right heart dysfunction after heart transplantation by Talha, Samy, Charloux, Anne, Piquard, François, Geny, Bernard

“…Heart transplantation (HT) should normalize cardiac endocrine function, but brain natriuretic peptide (BNP) levels remain elevated after HT, even in the…”
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Opposite effects of statins on mitochondria of cardiac and skeletal muscles: a 'mitohormesis' mechanism involving reactive oxygen species and PGC-1 by BOUITBIR, Jamal, CHARLES, Anne-Laure, ECHANIZ-LAGUNA, Andoni, KINDO, Michel, DAUSSIN, Frederic, AUWERX, Johan, PIQUARD, François, GENY, Bernard, ZOLL, Joffrey

“…Statins protect against cardiovascular-related mortality but induce skeletal muscle toxicity. To investigate mechanisms of statins, we tested the hypothesis…”
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Atorvastatin treatment reduces exercise capacities in rats: involvement of mitochondrial impairments and oxidative stress by BOUITBIR, Jamal, CHARLES, Anne-Laure, RASSENEUR, Laurence, DUFOUR, Stéphane, PIQUARD, François, GENY, Bernard, ZOLL, Joffrey

“…Physical exercise exacerbates the cytotoxic effects of statins in skeletal muscle. Mitochondrial impairments may play an important role in the development of…”
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Effect of angiotensin-converting enzyme inhibition on skeletal muscle oxidative function and exercise capacity in streptozotocin-induced diabetic rats by Rouyer, Olivier, Zoll, Joffrey, Daussin, Frederic, Damgé, Christiane, Helms, Pauline, Talha, Sami, Rasseneur, Laurence, Piquard, Francois, Geny, Bernard

“…Since exercise capacity is related to the mitochondrial respiration rate in skeletal muscle and both parameters are potentially modulated by the onset of…”
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Skeletal muscle mitochondrial dysfunction during chronic obstructive pulmonary disease: central actor and therapeutic target by Meyer, Alain, Zoll, Joffrey, Charles, Anne Laure, Charloux, Anne, de Blay, Frédéric, Diemunsch, Pierre, Sibilia, Jean, Piquard, François, Geny, Bernard

“…New Findings •  What is the topic of this review? Muscle dysfunction is a common complication and an important independent prognostic factor in chronic…”
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Mitochondria of trained skeletal muscle are protected from deleterious effects of statins by Bouitbir, Jamal, Daussin, Frédéric, Charles, Anne-Laure, Rasseneur, Laurence, Dufour, Stéphane, Richard, Ruddy, Piquard, François, Geny, Bernard, Zoll, Joffrey

“…Introduction: Statins are associated with adverse skeletal muscle effects. Our objective was to determine if muscular adaptations following exercise training…”
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Heart rate variability and intensity of habitual physical activity in middle-aged persons by BUCHHEIT, Martin, SIMON, Chantal, CHARLOUX, Anne, DOUTRELEAU, Stephane, PIQUARD, Francois, BRANDENBERGER, Gabrielle

“…In the middle-aged, it has been shown that moderate physical activity is associated with increased global HR variability (HRV) and vagal-related HRV indexes…”
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Left Ventricular Transmural Gradient in Mitochondrial Respiration Is Associated with Increased Sub-Endocardium Nitric Oxide and Reactive Oxygen Species Productions by Kindo, Michel, Gerelli, Sébastien, Bouitbir, Jamal, Hoang Minh, Tam, Charles, Anne-Laure, Mazzucotelli, Jean-Philippe, Zoll, Joffrey, Piquard, François, Geny, Bernard

“…Left ventricle (LV) transmural gradient in mitochondrial respiration has been recently reported. However, to date, the physiological mechanisms involved in the…”
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Inverse coupling between ultradian oscillations in delta wave activity and heart rate variability during sleep by Brandenberger, Gabrielle, Ehrhart, Jean, Piquard, François, Simon, Chantal

“…Objective: We investigate the relationship between changes in heart rate variability and electroencephalographic (EEG) activity during sleep. Method: Nine male…”
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Pretreatment with brain natriuretic peptide reduces skeletal muscle mitochondrial dysfunction and oxidative stress after ischemia-reperfusion by Talha, Samy, Bouitbir, Jamal, Charles, Anne-Laure, Zoll, Joffrey, Goette-Di Marco, Paola, Meziani, Ferhat, Piquard, François, Geny, Bernard

“…Brain natriuretic peptide (BNP) reduces the extent of myocardial infarction. We aimed to determine whether BNP may reduce skeletal muscle mitochondrial…”
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ACE inhibition prevents myocardial infarction-induced skeletal muscle mitochondrial dysfunction by Zoll, Joffrey, Monassier, Laurent, Garnier, Anne, N'Guessan, Benoit, Mettauer, Bertrand, Veksler, Vladimir, Piquard, Francois, Ventura-Clapier, Renee, Geny, Bernard

“…1 Service de Physiologie et d'Explorations Fonctionnelles, EA 3072 and 2 Laboratoire de Neurobiologie et de Pharmacologie Cardiovasculaire, INSERM U715,…”
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L-Arginine supplementation improves exercise capacity after a heart transplant by Doutreleau, Stéphane, Rouyer, Olivier, Di Marco, Paola, Lonsdorfer, Evelyne, Richard, Ruddy, Piquard, François, Geny, Bernard

“…BACKGROUND: Endothelial dysfunction is associated with the decreased exercise capacity observed in heart-transplant (HTx) recipients. L-Arginine…”
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