Search Results - "Pippin, J."
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Towards principles and policy levers for advancing living shorelines
Published in Journal of environmental management (01-06-2022)“…Living shorelines are often better alternatives to stabilize shorelines and reduce dangerous erosion compared to traditional hard armoring practices such as…”
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Leptin- and leptin receptor-deficient rodent models: relevance for human type 2 diabetes
Published in Current diabetes reviews (01-03-2014)“…Among the most widely used animal models in obesity-induced type 2 diabetes mellitus (T2DM) research are the congenital leptin- and leptin receptor-deficient…”
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Frontiers in assessing septic systems vulnerability in coastal Georgia, USA: Modeling approach and management implications
Published in PloS one (25-08-2021)“…Threats to public health and environmental quality from septic systems are more prevalent in areas with poorly draining soils, high water tables, or frequent…”
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Podocytes in culture: past, present, and future
Published in Kidney international (01-07-2007)“…Human genetic and in vivo studies have helped to define the critical importance of podocytes for kidney function in health and disease. However, as in any…”
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Shifting landscapes of risk: Quantifying pluvial flood vulnerability beyond the regulated floodplain
Published in Journal of environmental management (15-02-2022)“…Floods are recognized as the costliest type of natural hazard both worldwide and in the United States, with projected increases in frequency and magnitude in…”
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No landward movement: examining 80 years of population migration and shoreline change in Louisiana
Published in Population and environment (01-06-2019)“…Louisiana lost nearly 5,000 km² of its coastal land area due to relative sea level rise (including local, regional, and global factors driving relative sea…”
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Coronary Artery Calcium Score and Coronary Heart Disease Events in a Large Cohort of Asymptomatic Men and Women
Published in American journal of epidemiology (01-09-2005)“…Coronary artery calcium (CAC), a measure of subclinical coronary heart disease (CHD), may be useful in identifying asymptomatic persons at risk of CHD events…”
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Puromycin aminonucleoside induces oxidant-dependent DNA damage in podocytes in vitro and in vivo
Published in Kidney international (01-12-2006)“…A decline in podocyte number correlates with progression to glomerulosclerosis. A mechanism underlying reduced podocyte number is the podocyte's relative…”
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A Survey to Understand Public Opinion regarding Animal use in Medical Training
Published in Alternatives to laboratory animals (01-07-2018)“…A random survey was performed by ORC International Telephone CARAVAN®, on 24–27 March 2016, by trained interviewers. The aim of this survey was to gain further…”
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Darbepoetin alfa protects podocytes from apoptosis in vitro and in vivo
Published in Kidney international (01-08-2007)“…Detachment or apoptosis of podocytes leads to proteinuria and glomerulosclerosis. There are no current interventions for diabetic or non-diabetic glomerular…”
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Animal studies in spinal cord injury: a systematic review of methylprednisolone
Published in Alternatives to laboratory animals (01-02-2009)“…The objective of this study was to examine whether animal studies can reliably be used to determine the usefulness of methylprednisolone (MP) and other…”
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Taser Research in Pigs Not Helpful
Published in Journal of the American College of Cardiology (13-02-2007)“…Additional confounders include the use of anesthesia, controlled laboratory conditions, repetitive shocks in animals smaller than humans, and inability to…”
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Suppression of β-catenin inhibits the neoplastic growth of APC-mutant colon cancer cells
Published in Cancer research (Chicago, Ill.) (01-09-2001)“…Mutations involving the adenomatous polyposis coli (APC) tumor suppressorgene/beta-catenin signaling pathway have been identified in the majority of colon…”
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The subcellular localization of cyclin dependent kinase 2 determines the fate of mesangial cells: role in apoptosis and proliferation
Published in Oncogene (07-03-2002)“…Apoptosis is closely linked to proliferation. In this study we showed that inducing apoptosis in mouse mesangial cells with ultraviolet (UV) irradiation was…”
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Albumin-induced apoptosis of glomerular parietal epithelial cells is modulated by extracellular signal-regulated kinase 1/2
Published in Nephrology, dialysis, transplantation (01-04-2012)“…The biological role(s) of glomerular parietal epithelial cells (PECs) is not fully understood in health or disease. Given its location, PECs are constantly…”
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Of rodents and men: Species-specific glucose regulation and type 2 diabetes research
Published in ALTEX, alternatives to animal experimentation (2014)“…Type 2 diabetes mellitus (T2DM) has reached epidemic proportions worldwide and animal models mimicking human T2DM are widely used to study mechanisms of…”
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Of rodents and men: species-specific glucose regulation and type 2 diabetes research
Published in ALTEX, alternatives to animal experimentation (2014)“…Type 2 diabetes mellitus (T2DM) has reached epidemic proportions worldwide and animal models mimicking human T2DM are widely used to study mechanisms of…”
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Animal models of Alzheimer disease: historical pitfalls and a path forward
Published in ALTEX, alternatives to animal experimentation (2014)“…Alzheimer disease (AD) is a medically and financially overwhelming condition, and incidence rates are expected to triple by 2050.Despite decades of research in…”
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