Search Results - "Pippel, Dan"

Identification of benzofuran central cores for the inhibition of leukotriene A4 hydrolase by Eccles, Wendy, Blevitt, Jonathan M., Booker, Jamila N., Chrovian, Christa C., Crawford, Shelby, de Leon, Aimee Rose, Deng, Xiaohu, Fourie, Anne M., Grice, Cheryl A., Herman, Krystal, Karlsson, Lars, Kearney, Aaron M., Lee-Dutra, Alice, Liang, Jimmy, Luna, Rosa, Pippel, Dan, Rao, Navin, Riley, Jason P., Santillán, Alejandro, Savall, Brad, Tanis, Virginia M., Xue, Xiaohua, Young, Arlene L.

“…Leukotrienes (LT’s) are known to play a physiological role in inflammatory immune response. Leukotriene A4 hydrolase (LTA4H) is a cystolic enzyme that…”
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Optimization and biological evaluation of thiazole-bis-amide inverse agonists of RORγt by Gege, Christian, Albers, Michael, Kinzel, Olaf, Kleymann, Gerald, Schlüter, Thomas, Steeneck, Christoph, Hoffmann, Thomas, Xue, Xiaohua, Cummings, Maxwell D., Spurlino, John, Milligan, Cynthia, Fourie, Anne M., Edwards, James P., Leonard, Kristi, Coe, Kevin, Scott, Brian, Pippel, Dan, Goldberg, Steven D.

“…[Display omitted] The nuclear receptor retinoic acid receptor-related orphan receptor gamma t (RORγt) is a transcription factor that drives Th17 cell…”
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Identification of benzofuran central cores for the inhibition of leukotriene A(4) hydrolase by Eccles, Wendy, Blevitt, Jonathan M, Booker, Jamila N, Chrovian, Christa C, Crawford, Shelby, de Leon, Aimee Rose, Deng, Xiaohu, Fourie, Anne M, Grice, Cheryl A, Herman, Krystal, Karlsson, Lars, Kearney, Aaron M, Lee-Dutra, Alice, Liang, Jimmy, Luna, Rosa, Pippel, Dan, Rao, Navin, Riley, Jason P, Santillán, Alejandro, Savall, Brad, Tanis, Virginia M, Xue, Xiaohua, Young, Arlene L

“…Leukotrienes (LT's) are known to play a physiological role in inflammatory immune response. Leukotriene A(4) hydrolase (LTA(4)H) is a cystolic enzyme that…”
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Novel ketooxazole based inhibitors of fatty acid amide hydrolase (FAAH) by Timmons, Amy, Seierstad, Mark, Apodaca, Rich, Epperson, Matt, Pippel, Dan, Brown, Sean, Chang, Leon, Scott, Brian, Webb, Michael, Chaplan, Sandra R., Breitenbucher, J. Guy

“…Efforts to improve the properties of the well studied ketooxazole FAAH inhibitor OL-135 resulted in the discovery of a novel propylpiperidine series of FAAH…”
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