Search Results - "Pipier, A."
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Constrained G4 structures unveil topology specificity of known and new G4 binding proteins
Published in Scientific reports (29-06-2021)“…G-quadruplexes (G4) are non-canonical secondary structures consisting in stacked tetrads of hydrogen-bonded guanines bases. An essential feature of G4 is their…”
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Transcription-associated topoisomerase 2α (TOP2A) activity is a major effector of cytotoxicity induced by G-quadruplex ligands
Published in eLife (28-06-2021)“…G-quadruplexes (G4) are non-canonical DNA structures found in the genome of most species including human. Small molecules stabilizing these structures, called…”
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Journal Article