Search Results - "Piper, Rob"

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  1. 1

    Abstract B01: Genome-scale shRNA screen provides insight into the role of CUL3 in adaptive mechanisms of resistance to mutant BRAF inhibition by Vanneste, Marion, Zhu, Eliot, Feddersen, Charlotte, Varzavand, Afshin, Foley, Tyler, Zhao, Lei, Piper, Rob, Stipp, Christopher, Dupuy, Adam, Henry, Michael

    Published in Cancer research (Chicago, Ill.) (01-10-2020)
    “…Abstract MAPK inhibition with targeted BRAF inhibitors has revolutionized the treatment of BRAF-mutant melanoma. However, in most cases, the effects of mutant…”
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    Journal Article
  2. 2

    PDADMAC flocculation of Chinese hamster ovary cells: Enabling a centrifuge-less harvest process for monoclonal antibodies by McNerney, Thomas, Thomas, Anne, Senczuk, Anna, Petty, Krista, Zhao, Xiaoyang, Piper, Rob, Carvalho, Juliane, Hammond, Matthew, Sawant, Satin, Bussiere, Jeanine

    Published in mAbs (04-03-2015)
    “…High titer (>10 g/L) monoclonal antibody (mAb) cell culture processes are typically achieved by maintaining high viable cell densities over longer culture…”
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  3. 3

    Robust depth filter sizing for centrate clarification by Lutz, Herb, Chefer, Kate, Felo, Michael, Cacace, Benjamin, Hove, Sarah, Wang, Bin, Blanchard, Mark, Oulundsen, George, Piper, Rob, Zhao, Xiaoyang

    Published in Biotechnology progress (01-11-2015)
    “…Cellulosic depth filters embedded with diatomaceous earth are widely used to remove colloidal cell debris from centrate as a secondary clarification step…”
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    Journal Article
  4. 4

    Monoclonal antibody disulfide reduction during manufacturing: Untangling process effects from product effects by Hutterer, Katariina M., Hong, Robert W., Lull, Jonathon, Zhao, Xiaoyang, Wang, Tian, Pei, Rex, Le, M. Eleanor, Borisov, Oleg, Piper, Rob, Liu, Yaoqing Diana, Petty, Krista, Apostol, Izydor, Flynn, Gregory C.

    Published in mAbs (01-07-2013)
    “…Manufacturing-induced disulfide reduction has recently been reported for monoclonal human immunoglobulin gamma (IgG) antibodies, a widely used modality in the…”
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    Journal Article
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