Search Results - "Piper, Rob"
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Abstract B01: Genome-scale shRNA screen provides insight into the role of CUL3 in adaptive mechanisms of resistance to mutant BRAF inhibition
Published in Cancer research (Chicago, Ill.) (01-10-2020)“…Abstract MAPK inhibition with targeted BRAF inhibitors has revolutionized the treatment of BRAF-mutant melanoma. However, in most cases, the effects of mutant…”
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PDADMAC flocculation of Chinese hamster ovary cells: Enabling a centrifuge-less harvest process for monoclonal antibodies
Published in mAbs (04-03-2015)“…High titer (>10 g/L) monoclonal antibody (mAb) cell culture processes are typically achieved by maintaining high viable cell densities over longer culture…”
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Robust depth filter sizing for centrate clarification
Published in Biotechnology progress (01-11-2015)“…Cellulosic depth filters embedded with diatomaceous earth are widely used to remove colloidal cell debris from centrate as a secondary clarification step…”
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Monoclonal antibody disulfide reduction during manufacturing: Untangling process effects from product effects
Published in mAbs (01-07-2013)“…Manufacturing-induced disulfide reduction has recently been reported for monoclonal human immunoglobulin gamma (IgG) antibodies, a widely used modality in the…”
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PAPERS IN AGRICULTURE
Published in Transactions of the Society, Instituted at London, for the Encouragement of Arts, Manufactures, and Commerce (01-01-1799)Get full text
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