Search Results - "Piper, H.M"

Growth differentiation factor 15 acts anti-apoptotic and pro-hypertrophic in adult cardiomyocytes by Heger, J., Schiegnitz, E., von Waldthausen, D., Anwar, M.M., Piper, H.M., Euler, G.

“…Growth differentiation factor 15 (GDF15) is induced during heart failure development, and may influence different processes in cardiac remodeling. While its…”
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Role of Redox Signaling in the Autonomous Proliferative Response of Endothelial Cells to Hypoxia by Schäfer, M, Schäfer, C, Ewald, N, Piper, H M, Noll, Th

“…ABSTRACT—Endothelial cells exhibit an autonomous proliferative response to hypoxia, independent of paracrine effectors. In cultured endothelial cells of…”
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Preconditioning with diazoxide prevents reoxygenation-induced rigor-type hypercontracture by Abdallah, Y, Wolf, C, Meuter, K, Piper, H.M, Reusch, H.P, Ladilov, Y

“…Abstract Ischemic preconditioning has a powerful protective potential against a reperfusion-induced injury of the post-ischemic myocardium. Cardiomyocyte…”
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Transgenic overexpression of the adenine nucleotide translocase 1 protects cardiomyocytes against TGFβ1 -induced apoptosis by stabilization of the mitochondrial permeability transition pore by Heger, J, Abdallah, Y, Shahzad, T, Klumpe, I, Piper, H.M, Schultheiss, H.-P, Schlüter, K.-D, Schulz, R, Euler, G, Dörner, A

“…Abstract Aims Since adenine nucleotide translocase 1 (ANT1) overexpression improved cardiac function in rats with activated renin–angiotensin system (RAS) and…”
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Stimulation of CGMP signaling provides protection of endothelial cells to reperfusion injury by Kasseckert, S.A, Schaefer, C, Piper, H.M, Abdallah, Y

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Simulated Ischemia Increases the Susceptibility of Rat Cardiomyocytes to Hypercontracture by Ladilov, Y.V, Siegmund, B, Balser, C, Piper, H.M

“…The hypothesis that rat cardiomyocytes become susceptible to hypercontracture after anoxia/reoxygenation was investigated. The cells were gradually overloaded…”
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Nitric oxide production by cultured aortic endothelial cells in response to thiol depletion and replenishment by MURPHY, M. E, PIPER, H. M, WATANABE, H, SIES, H

“…The requirements and influence of thiols on the production of nitric oxide (NO) were examined in cultured porcine aortic endothelial cells. NO production was…”
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Alpha- and beta-adrenergic stimulation of protein synthesis in cultured adult ventricular cardiomyocytes by Pinson, A, Schlüter, K D, Zhou, X J, Schwartz, P, Kessler-Icekson, G, Piper, H M

“…The effect of the alpha 1-adrenoceptor agonist phenylephrine (PE, 1-10 microM) and the beta-adrenoceptor agonist isoprenaline (ISO, 1-10 microM) on protein…”
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Metabolic Recovery of Isolated Adult Rat Cardiomyocytes after Energy Depletion: Existence of an ATP Threshold? by Bonz, A., Siegmund, B., Ladilov, Y., Vahl, C.F., Piper, H.M.

“…The question was investigated whether cardiomyocytes can be resuscitated after extreme energy depletion, i.e. after loss of ATP >70%. Isolated ventricular…”
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Extracellular ATP attenuates ischemia-induced caspase-3 cleavage in human endothelial cells by Urban, D., Härtel, F.V., Gadiraju, K., Gündüz, D., Aslam, M., Piper, H.M., Noll, T.

“…► Ischemia-induced apoptosis is accompanied by ATP release from endothelial cells. ► Inhibition of ATP breakdown reduces ischemia-induced endothelial cell…”
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Quercetin-induced induction of the NO/cGMP pathway depends on Ca2+-activated K+ channel-induced hyperpolarization-mediated Ca2+-entry into cultured human endothelial cells by Kuhlmann, Christoph R, Schaefer, Christian A, Kosok, Christoph, Abdallah, Yaser, Walther, Sabine, Lüdders, Dörte W, Neumann, Thomas, Tillmanns, Harald, Schäfer, Claudia, Piper, Hans M, Erdogan, Ali

“…Quercetin is one of the dietary-derived flavonoids that are held responsible for the beneficial effects of red wine drinking in coronary artery disease known…”
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Direct effects of the angiotensin-converting enzyme inhibitor ramiprilat on adult rat ventricular cardiomyocytes by Helmig, S, Schuckenböhmer, P, Heger, J, Euler, G, Piper, H.M, Schlüter, K.-D

“…Angiotensin-converting enzyme (ACE) inhibitors like ramiprilat bind to ACE expressed on the cell surface of endothelial cells and induce cell-specific…”
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Hypertrophy-associated Gene Induction after β -Adrenergic Stimulation in Adult Cardiomyocytes by Taimor, G., Schlüter, K.-D., Piper, H.M.

“…In isolated cardiomyocytes, hypertrophic responsiveness to β -adrenergic stimulation can be induced by pre-exposure of the cells to TGF- β. To characterize…”
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Activation of p70S6Kinase byβ-adrenoceptor Agonists on Adult Cardiomyocytes by Simm, A., Schlüter, K.-D., Diez, C., Piper, H.M., Hoppe, J.

“…Cardiac cellular hypertrophy plays an important role in cardiovascular diseases. Up until now, little has been known about the regulation of cellular growth on…”
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Cell cultures of adult cardiomyocytes as models of the myocardium by Jacobson, S L, Piper, H M

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Protection of energy status of hypoxic cardiomyocytes by mild acidosis by Koop, A, Piper, H M

“…The question was investigated whether mild acidosis can provide energetic protection on the hypoxic myocardial cell by mechanisms other than negative inotropy…”
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Culturing of calcium stable adult cardiac myocytes by Piper, H M, Probst, I, Schwartz, P, Hütter, F J, Spieckermann, P G

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Protection of isolated cardiomyocytes against reoxygenation-induced hypercontracture by SIN-1C by Siegmund, B, Balser, C, Ladilov, Y V, Piper, H M

“…Previous studies have shown that SIN-1C (N-morpholinoiminoacetonitrile) can protect ischemic-reperfused myocardium. The aim of the present study was to analyse…”
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What constitutes the calcium paradox? by Altschuld, R A, Ganote, C E, Nayler, W G, Piper, H M

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Evidence for adenylate cyclase-coupled A1-adenosine receptors on ventricular cardiomyocytes from adult rat and dog heart by Henrich, M, Piper, H M, Schrader, J

“…Isolated metabolically stable cardiomyocytes from adult rats and mongrel dogs were used to characterize the mechanism underlying the antiadrenergic effect of…”
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