Search Results - "Piper, D W"

Commensal bacteria and essential amino acids control food choice behavior and reproduction by Leitão-Gonçalves, Ricardo, Carvalho-Santos, Zita, Francisco, Ana Patrícia, Fioreze, Gabriela Tondolo, Anjos, Margarida, Baltazar, Célia, Elias, Ana Paula, Itskov, Pavel M, Piper, Matthew D W, Ribeiro, Carlos

“…Choosing the right nutrients to consume is essential to health and wellbeing across species. However, the factors that influence these decisions are poorly…”
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Quantification of food intake in Drosophila by Wong, Richard, Piper, Matthew D W, Wertheim, Bregje, Partridge, Linda

“…Measurement of food intake in the fruit fly Drosophila melanogaster is often necessary for studies of behaviour, nutrition and drug administration. There is no…”
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Biosynthetic constraints on amino acid synthesis at the base of the food chain may determine their use in higher-order consumer genomes by Gómez Ortega, Javier, Raubenheimer, David, Tyagi, Sonika, Mirth, Christen K, Piper, Matthew D W

“…Dietary nutrient composition is essential for shaping important fitness traits and behaviours. Many organisms are protein limited, and for Drosophila…”
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Amino-acid imbalance explains extension of lifespan by dietary restriction in Drosophila by Grandison, Richard C, Piper, Matthew D.W, Partridge, Linda

“…Dietary restriction extends healthy lifespan in diverse organisms and reduces fecundity. It is widely assumed to induce adaptive reallocation of nutrients from…”
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Early-adult methionine restriction reduces methionine sulfoxide and extends lifespan in Drosophila by Kosakamoto, Hina, Obata, Fumiaki, Kuraishi, Junpei, Aikawa, Hide, Okada, Rina, Johnstone, Joshua N., Onuma, Taro, Piper, Matthew D. W., Miura, Masayuki

“…Methionine restriction (MetR) extends lifespan in various organisms, but its mechanistic understanding remains incomplete. Whether MetR during a specific…”
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Restriction of essential amino acids dictates the systemic metabolic response to dietary protein dilution by Yap, Yann W., Rusu, Patricia M., Chan, Andrea Y., Fam, Barbara C., Jungmann, Andreas, Solon-Biet, Samantha M., Barlow, Christopher K., Creek, Darren J., Huang, Cheng, Schittenhelm, Ralf B., Morgan, Bruce, Schmoll, Dieter, Kiens, Bente, Piper, Matthew D. W., Heikenwälder, Mathias, Simpson, Stephen J., Bröer, Stefan, Andrikopoulos, Sofianos, Müller, Oliver J., Rose, Adam J.

“…Dietary protein dilution (DPD) promotes metabolic-remodelling and -health but the precise nutritional components driving this response remain elusive. Here, by…”
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A defined diet for pre-adult Drosophila melanogaster by Martelli, Felipe, Quig, Annelise, Mele, Sarah, Lin, Jiayi, Fulton, Tahlia L., Wansbrough, Mia, Barlow, Christopher K., Schittenhelm, Ralf B., Johnson, Travis K., Piper, Matthew D. W.

“…Drosophila melanogaster is unique among animal models because it has a fully defined synthetic diet available to study nutrient-gene interactions. However, use…”
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Calories do not explain extension of life span by dietary restriction in Drosophila by Mair, William, Piper, Matthew D W, Partridge, Linda

“…Dietary restriction (DR) extends life span in diverse organisms, including mammals, and common mechanisms may be at work. DR is often known as calorie…”
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Longer Lifespan, Altered Metabolism, and Stress Resistance in Drosophila from Ablation of Cells Making Insulin-Like Ligands by Broughton, Susan J., Matthew D. W. Piper, Ikeya, Tomoatsu, Bass, Timothy M., Jacobson, Jake, Driege, Yasmine, Martinez, Pedro, Hafen, Ernst, Withers, Dominic J., Leevers, Sally J., Partridge, Linda, Kenyon, Cynthia J.

“…The insulin/insulin-like growth factor-like signaling pathway, present in all multicellular organisms, regulates diverse functions including growth,…”
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QuantiFly: Robust Trainable Software for Automated Drosophila Egg Counting by Waithe, Dominic, Rennert, Peter, Brostow, Gabriel, Piper, Matthew D W

“…We report the development and testing of software called QuantiFly: an automated tool to quantify Drosophila egg laying. Many laboratories count Drosophila…”
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Dietary restriction in Drosophila: delayed aging or experimental artefact? by Piper, Matthew D W, Partridge, Linda

“…Lifespan can be extended by reduction of dietary intake. This practice is referred to as dietary restriction (DR), and extension of lifespan by DR is…”
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Effect of a standardised dietary restriction protocol on multiple laboratory strains of Drosophila melanogaster by Grandison, Richard C, Wong, Richard, Bass, Timothy M, Partridge, Linda, Piper, Matthew D W

“…Outcomes of lifespan studies in model organisms are particularly susceptible to variations in technical procedures. This is especially true of dietary…”
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Ancient deep-sea sponge grounds on the Flemish Cap and Grand Bank, northwest Atlantic by Murillo, F. J, Kenchington, E, Lawson, J. M, Li, G, Piper, D. J. W

“…Recent studies on deep-sea sponges have focused on mapping contemporary distributions while little work has been done to map historical distributions;…”
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Detrimental effects of RNAi: a cautionary note on its use in Drosophila ageing studies by Alic, Nazif, Hoddinott, Matthew P, Foley, Andrea, Slack, Cathy, Piper, Matthew D W, Partridge, Linda

“…RNA interference (RNAi) provides an important tool for gene function discovery. It has been widely exploited in Caenorhabditis elegans ageing research because…”
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Identification and characterization of phenylpyruvate decarboxylase genes in Saccharomyces cerevisiae by Vuralhan, Z, Morais, M.A, Tai, S.L, Piper, M.D.W, Pronk, J.T

“…Catabolism of amino acids via the Ehrlich pathway involves transamination to the corresponding alpha-keto acids, followed by decarboxylation to an aldehyde and…”
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Directed evolution of pyruvate decarboxylase-negative Saccharomyces cerevisiae, yielding a C2-independent, glucose-tolerant, and pyruvate-hyperproducing yeast by Maris, A.J.A. van, Geertman, J.M.A, Vermeulen, A, Groothuizen, M.K, Winkler, A.A, Piper, M.D.W, Dijken, J.P. van, Pronk, J.T

“…The absence of alcoholic fermentation makes pyruvate decarboxylase-negative (Pdc-) strains of Saccharomyces cerevisiae an interesting platform for further…”
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Optimization of Dietary Restriction Protocols in Drosophila by Bass, Timothy M., Grandison, Richard C., Wong, Richard, Martinez, Pedro, Partridge, Linda, Piper, Matthew D. W.

“…Dietary restriction (DR) extends life span in many organisms, through unknown mechanisms that may or may not be evolutionarily conserved. Because different…”
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Sex and genotype effects on nutrient-dependent fitness landscapes in Drosophila melanogaster by Camus, M. Florencia, Fowler, Kevin, Piper, Matthew W. D., Reuter, Max

“…The sexes perform different reproductive roles and have evolved sometimes strikingly different phenotypes. One focal point of adaptive divergence occurs in the…”
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Sexual dimorphism in the nutritional requirement for adult lifespan in Drosophila melanogaster by Wu, Qi, Yu, Guixiang, Cheng, Xingyi, Gao, Yue, Fan, Xiaolan, Yang, Deying, Xie, Meng, Wang, Tao, Piper, Matthew D. W., Yang, Mingyao

“…The nutritional requirements of Drosophila have mostly been studied for development and reproduction, but the minimal requirements for adult male and female…”
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Using Mouse and Drosophila Models to Investigate the Mechanistic Links between Diet, Obesity, Type II Diabetes, and Cancer by Warr, Coral G, Shaw, Katherine H, Azim, Arani, Piper, Matthew D W, Parsons, Linda M

“…Many of the links between diet and cancer are controversial and over simplified. To date, human epidemiological studies consistently reveal that patients who…”
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