Search Results - "Piotr Rekowski"

Transportan 10 improves the pharmacokinetics and pharmacodynamics of vancomycin by Ruczyński, Jarosław, Rusiecka, Izabela, Turecka, Katarzyna, Kozłowska, Agnieszka, Alenowicz, Magdalena, Gągało, Iwona, Kawiak, Anna, Rekowski, Piotr, Waleron, Krzysztof, Kocić, Ivan

“…In the presented study, transportan 10 (TP10), an amphipathic cell penetrating peptide (CPP) with high translocation activity, was conjugated with vancomycin…”
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Structure–Activity Relationship of New Chimeric Analogs of Mastoparan from the Wasp Venom Paravespula lewisii by Ruczyński, Jarosław, Parfianowicz, Brygida, Mucha, Piotr, Wiśniewska, Katarzyna, Piechowicz, Lidia, Rekowski, Piotr

“…Mastoparan (MP) is an antimicrobial cationic tetradecapeptide with the primary structure INLKALAALAKKIL-NH2. This amphiphilic α-helical peptide was originally…”
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TP10-Dopamine Conjugate as a Potential Therapeutic Agent in the Treatment of Parkinson’s Disease by Rusiecka, Izabela, Ruczyński, Jarosław, Kozłowska, Agnieszka, Backtrog, Ewelina, Mucha, Piotr, Kocić, Ivan, Rekowski, Piotr

“…Parkinson’s disease (PD) is a common progressive neurodegenerative disorder for which the current treatment is not fully satisfactory. One of the major…”
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The Application of Peptide Nucleic Acids (PNA) in the Inhibition of Proprotein Convertase Subtilisin/Kexin 9 ( PCSK9 ) Gene Expression in a Cell-Free Transcription/Translation System by Polak, Agnieszka, Machnik, Grzegorz, Bułdak, Łukasz, Ruczyński, Jarosław, Prochera, Katarzyna, Bujak, Oliwia, Mucha, Piotr, Rekowski, Piotr, Okopień, Bogusław

“…Proprotein convertase subtilisin/kexin 9 (PCSK9) is a protein that plays a key role in the metabolism of low-density lipoprotein (LDL) cholesterol. The…”
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Interaction of Arginine-Rich Cell-Penetrating Peptides with an Artificial Neuronal Membrane by Mucha, Piotr, Sikorska, Emilia, Rekowski, Piotr, Ruczyński, Jarosław

“…Arginine-rich cell-penetrating peptides (RRCPPs) exhibit intrinsic neuroprotective effects on neurons injured by acute ischemic stroke. Conformational…”
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Solid Phase Synthesis and TAR RNA-Binding Activity of Nucleopeptides Containing Nucleobases Linked to the Side Chains via 1,4-Linked-1,2,3-triazole by Mucha, Piotr, Pieszko, Małgorzata, Bylińska, Irena, Wiczk, Wiesław, Ruczyński, Jarosław, Prochera, Katarzyna, Rekowski, Piotr

“…Nucleopeptides (NPs) represent synthetic polymers created by attaching nucleobases to the side chains of amino acid residues within peptides. These compounds…”
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PTD4 Peptide Increases Neural Viability in an In Vitro Model of Acute Ischemic Stroke by Mazuryk, Jarosław, Puchalska, Izabela, Koziński, Kamil, Ślusarz, Magdalena J., Ruczyński, Jarosław, Rekowski, Piotr, Rogujski, Piotr, Płatek, Rafał, Wiśniewska, Marta Barbara, Piotrowski, Arkadiusz, Janus, Łukasz, Skowron, Piotr M., Pikuła, Michał, Sachadyn, Paweł, Rodziewicz-Motowidło, Sylwia, Czupryn, Artur, Mucha, Piotr

“…Ischemic stroke is a disturbance in cerebral blood flow caused by brain tissue ischemia and hypoxia. We optimized a multifactorial in vitro model of acute…”
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Novel, Highly Selective RT-QPCR Method for Quantification of MSRV Using PNA Clamping Syncytin-1 (ERVWE1) by Machnik, Grzegorz, Skudrzyk, Estera, Bułdak, Łukasz, Łabuzek, Krzysztof, Ruczyński, Jarosław, Alenowicz, Magdalena, Rekowski, Piotr, Nowak, Piotr Jan, Okopień, Bogusław

“…HERV-W is a multi-locus family of human endogenous retroviruses (HERVs) that has been found to play an important role in human physiology and pathology. Two…”
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Synthesis and hybridization studies of a new CPP-PNA conjugate as a potential therapeutic agent in atherosclerosis treatment by Wojciechowska, Monika, Ruczyński, Jaroslaw, Rekowski, Piotr, Alenowicz, Magdalena, Mucha, Piotr, Pieszko, Małgorzata, Miszka, Anna, Dobkowski, Michał, Bluijssen, Hans

“…The objective of this study was to design and synthesize a new CPP-PNA conjugate that would be able to penetrate endothelial cells, bind STAT1 mRNA and thereby…”
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Aspartimide modified galanin analogue antagonizes galanin action on insulin secretion by Ruczyński, Jarosław, Konstański, Zdzisław, Cybal, Magdalena, Kocić, Ivan, Rekowski, Piotr

“…Aspartimide (Asi) formation is one of the most serious side reactions that can occur both during solid phase synthesis and storage of peptides containing…”
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Capillary electrophoresis study of systemin peptides spreading in tomato plant by Mucha, Piotr, Ruczynski, Jaroslaw, Dobkowski, Michal, Backtrog, Ewelina, Rekowski, Piotr

“…Systemin (Sys) is an 18‐aa plant peptide hormone involved in the regulation of plant's defensive response. Sys is considered as a fast‐spreading systemic wound…”
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The Application of Peptide Nucleic Acids Gene Expression in a Cell-Free Transcription/Translation System by Polak, Agnieszka, Machnik, Grzegorz, Bułdak, Łukasz, Ruczyński, Jarosław, Prochera, Katarzyna, Bujak, Oliwia, Mucha, Piotr, Rekowski, Piotr, Okopień, Bogusław

“…Proprotein convertase subtilisin/kexin 9 (PCSK9) is a protein that plays a key role in the metabolism of low-density lipoprotein (LDL) cholesterol. The…”
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Transportan 10 improves the anticancer activity of cisplatin by Izabela, Rusiecka, Jarosław, Ruczyński, Magdalena, Alenowicz, Piotr, Rekowski, Ivan, Kocić

“…The aim of this paper was to examine whether cell-penetrating peptides (CPPs) such as transportan 10 (TP10) or protein transduction domain (PTD4) may improve…”
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Sequence-altered peptide adopts optimum conformation for modification-dependent binding of the yeast tRNAPhe anticodon domain by Mucha, Piotr, Szyk, Agnieszka, Rekowski, Piotr, Agris, Paul F

“…Amino acid contributions to protein recognition of naturally modified RNAs are not understood. Circular dichroism spectra and predictive software suggested…”
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Publisher Correction: Transportan 10 improves the pharmacokinetics and pharmacodynamics of vancomycin by Ruczyński, Jarosław, Rusiecka, Izabela, Turecka, Katarzyna, Kozłowska, Agnieszka, Alenowicz, Magdalena, Gągało, Iwona, Kawiak, Anna, Rekowski, Piotr, Waleron, Krzysztof, Kocić, Ivan

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Anticodon Domain Methylated Nucleosides of Yeast tRNAPhe Are Significant Recognition Determinants in the Binding of a Phage Display Selected Peptide by Mucha, Piotr, Szyk, Agnieszka, Rekowski, Piotr, Weiss, Patrick A, Agris, Paul F

“…The contributions of the natural modified nucleosides to RNA identity in protein/RNA interactions are not understood. We had demonstrated that 15 amino acid…”
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Erratum to: Transportan 10 improves the anticancer activity of cisplatin by Rusiecka, Izabela, Ruczyński, Jarosław, Alenowicz, Magdalena, Rekowski, Piotr, Kocić, Ivan

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Cell-penetrating peptides as a promising tool for delivery of various molecules into the cells by Ruczynski, Jaroslaw, Wierzbicki, Piotr M, Kogut-Wierzbicka, Marzena, Mucha, Piotr, Siedlecka-Kroplewska, Kamila, Rekowski, Piotr

“…Many biologically active compounds, including macromolecules that are used as various kinds of drugs, must be delivered to the interior of cell or organelles…”
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Monitoring the Transcriptional Activity of Human Endogenous Retroviral HERV-W Family Using PNA Strand Invasion into Double-Stranded DNA by Machnik, Grzegorz, Skudrzyk, Estera, Bułdak, Łukasz, Ruczyński, Jarosław, Kozłowska, Agnieszka, Mucha, Piotr, Rekowski, Piotr, Szkróbka, Witold, Basiak, Marcin, Bołdys, Aleksandra, Sławska, Helena, Okopień, Bogusław

“…In the presented assay, we elaborated a method for distinguishing sequences that are genetically closely related to each other. This is particularly important…”
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The application of strand invasion phenomenon, directed by peptide nucleic acid (PNA) and single‐stranded DNA binding protein (SSB) for the recognition of specific sequences of human endogenous retroviral HERV‐W family by Machnik, Grzegorz, Bułdak, Łukasz, Ruczyński, Jarosław, Gąsior, Tomasz, Huzarska, Małgorzata, Belowski, Dariusz, Alenowicz, Magdalena, Mucha, Piotr, Rekowski, Piotr, Okopień, Bogusław

“…The HERV‐W family of human endogenous retroviruses represents a group of numerous sequences that show close similarity in genetic composition. It has been…”
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