Search Results - "Piontini, Andrea"
-
1
MFSD2A Promotes Endothelial Generation of Inflammation-Resolving Lipid Mediators and Reduces Colitis in Mice
Published in Gastroenterology (New York, N.Y. 1943) (01-11-2017)“…Alterations in signaling pathways that regulate resolution of inflammation (resolving pathways) contribute to pathogenesis of ulcerative colitis (UC). The…”
Get full text
Journal Article -
2
Unveiling role of sphingosine-1-phosphate receptor 2 as a brake of epithelial stem cell proliferation and a tumor suppressor in colorectal cancer
Published in Journal of experimental & clinical cancer research (23-11-2020)“…Background Sphingosine-1-phosphate receptor 2 (S1PR2) mediates pleiotropic functions encompassing cell proliferation, survival, and migration, which become…”
Get full text
Journal Article -
3
Pin1 is required for sustained B cell proliferation upon oncogenic activation of Myc
Published in Oncotarget (19-04-2016)“…The c-myc proto-oncogene is activated by translocation in Burkitt's lymphoma and substitutions in codon 58 stabilize the Myc protein or augment its oncogenic…”
Get full text
Journal Article -
4
The chemerin/CMKLR1 axis regulates intestinal graft-versus-host disease
Published in JCI insight (08-03-2023)“…Gastrointestinal graft-versus-host disease (GvHD) is a major cause of mortality and morbidity following allogeneic bone marrow transplantation (allo-BMT)…”
Get full text
Journal Article -
5
Reciprocal influence of B cells and tumor macro and microenvironments in the ApcMin/+ model of colorectal cancer
Published in Oncoimmunology (01-01-2017)“…One of the most fascinating aspects of the immune system is its dynamism, meant as the ability to change and readapt according to the organism needs. Following…”
Get full text
Journal Article -
6
The interaction between uPAR and vitronectin triggers ligand-independent adhesion signalling by integrins
Published in The EMBO journal (03-11-2014)“…The urokinase‐type plasminogen activator receptor (uPAR) is a non‐integrin vitronectin (VN) cell adhesion receptor linked to the plasma membrane by a…”
Get full text
Journal Article -
7
Sphingosine‐1‐phosphate receptor 2 is a negative regulator of epithelial cell proliferation and intestinal tumorigenesis
Published in The FASEB journal (01-04-2017)“…Abstract only Sphingosine‐1‐phosphate (S1P) is a bioactive sphingolipid metabolite, involved in several cellular processes through the activation of the five G…”
Get full text
Journal Article -
8
Treatment with a Urokinase Receptor-derived Cyclized Peptide Improves Experimental Colitis by Preventing Monocyte Recruitment and Macrophage Polarization
Published in Inflammatory bowel diseases (01-10-2016)“…Leukocyte migration across the blood barrier and into tissues represents a key process in the pathogenesis of inflammatory bowel diseases. The urokinase…”
Get full text
Journal Article -
9
-
10
-
11
Abstract B10: Genome-wide analysis of p53 transcriptional programs in Myc-induced lymphomas
Published in Molecular cancer research (01-10-2015)“…Oncogenic activation of Myc induces cellular transformation and hyper-proliferation, while it activates intrinsic tumor surveillance pathways aimed at…”
Get full text
Journal Article -
12
Abstract B03: Pin1 is required for sustained B cell proliferation upon oncogenic activation of Myc
Published in Molecular cancer research (01-10-2015)“…The c-myc proto-oncogene is activated by translocation in Burkitt's lymphoma, where it is also frequently subject to secondary mutations. Substitutions in…”
Get full text
Journal Article -
13
-
14
-
15
Dual regulation of Myc by Abl
Published in Oncogene (07-11-2013)“…The tyrosine kinase c-Abl (or Abl) and the prolyl-isomerase Pin1 cooperatively activate the transcription factor p73 by enhancing recruitment of the…”
Get full text
Journal Article -
16
Reciprocal influence of B cells and tumor macro and microenvironments in the Apc Min/+ model of colorectal cancer
Published in Oncoimmunology (03-08-2017)“…One of the most fascinating aspects of the immune system is its dynamism, meant as the ability to change and readapt according to the organism needs. Following…”
Get full text
Journal Article