Search Results - "Pioletti, Dominique P"
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Cartilage Repair: Promise of Adhesive Orthopedic Hydrogels
Published in International journal of molecular sciences (16-09-2024)“…Cartilage repair remains a major challenge in human orthopedic medicine, necessitating the application of innovative strategies to overcome existing technical…”
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Effects of glenoid inclination and acromion index on humeral head translation and glenoid articular cartilage strain
Published in Journal of shoulder and elbow surgery (01-01-2017)“…Background Previous clinical studies have reported associations between glenoid inclination (GI), the acromion index (AI), and the critical shoulder angle…”
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3
Design of Customized Mouthguards with Superior Protection Using Digital-Based Technologies and Impact Tests
Published in Sports medicine - open (31-05-2024)“…Background In contact sports, an impact on the jaw can generate destructive stress on the tooth-bone system. Mouthguards can be beneficial in reducing the…”
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Anti-Microbial Dendrimers against Multidrug-Resistant P. aeruginosa Enhance the Angiogenic Effect of Biological Burn-wound Bandages
Published in Scientific reports (25-02-2016)“…Multi-drug resistant Pseudomonas aeruginosa has increased progressively and impedes further regression in mortality in burn patients. Such wound infections…”
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5
Temperature evolution following joint loading promotes chondrogenesis by synergistic cues via calcium signaling
Published in eLife (08-03-2022)“…During loading of viscoelastic tissues, part of the mechanical energy is transformed into heat that can locally increase the tissue temperature, a phenomenon…”
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6
Nano Surface‐Heterogeneities of Particles Modulate the Macroscopic Properties of Hydrogels
Published in Advanced materials interfaces (01-05-2023)“…Nanoparticles, when incorporated into polymer matrices, can improve the intrinsic properties of composite materials. These materials possess fascinating…”
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7
Fatigue as the missing link between bone fragility and fracture
Published in Nature biomedical engineering (01-02-2018)“…The prevention of fragility fractures in bone—pathologic fractures resulting from daily activity and mostly occurring in the elderly population—has been a…”
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8
A Flow Sensing Model for Mesenchymal Stromal Cells Using Morphogen Dynamics
Published in Biophysical journal (21-05-2013)“…The differentiation of mesenchymal stromal cells has been shown to be affected by many parameters such as morphogens, flow rate, medium viscosity, and shear…”
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Banked Primary Progenitor Cells for Allogeneic Intervertebral Disc (IVD) Therapy: Preclinical Qualification and Functional Optimization within a Cell Spheroid Formulation Process
Published in Pharmaceutics (29-09-2024)“…Biological products are emerging as therapeutic management options for intervertebral disc (IVD) degenerative affections and lower back pain. Autologous and…”
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10
An Adhesive Hydrogel Technology for Enhanced Cartilage Repair: A Preliminary Proof of Concept
Published in Gels (14-10-2024)“…Knee cartilage has limited natural healing capacity, complicating the development of effective treatment plans. Current non-cell-based therapies (e.g.,…”
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Unraveling cartilage degeneration through synergistic effects of hydrostatic pressure and biomimetic temperature increase
Published in iScience (15-12-2023)“…Cartilage degeneration, typically viewed as an irreversible, vicious cycle, sees a significant reduction in two essential biophysical cues: the…”
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12
Integration of mechanotransduction concepts in bone tissue engineering
Published in Computer methods in biomechanics and biomedical engineering (01-10-2013)“…Mechanical stimulus has been identified for a long time as a key player in the adaptation of the musculo-skeletal tissues to their function. Mechanical loading…”
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13
Osteogenesis imperfecta: from diagnosis and multidisciplinary treatment to future perspectives
Published in Swiss medical weekly (2016)“…Osteogenesis imperfecta is an inherited connective tissue disorder with wide phenotypic and molecular heterogeneity. A common issue associated with the…”
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14
Low-oxygen tension augments chondrocyte sensitivity to biomimetic thermomechanical cues in cartilage-engineered constructs
Published in iScience (18-08-2023)“…Chondrocytes respond to various biophysical cues, including oxygen tension, transient thermal signals, and mechanical stimuli. However, understanding how these…”
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15
Wet adhesive hydrogels to correct malacic trachea (tracheomalacia) A proof of concept
Published in iScience (21-07-2023)“…Tracheomalacia (TM) is a condition characterized by a weak tracheal cartilage and/or muscle, resulting in excessive collapse of the airway in the newborns…”
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Human Bone Progenitor Cells for Clinical Application: What Kind of Immune Reaction Does Fetal Xenograft Tissue Trigger in Immunocompetent Rats?
Published in Cell transplantation (01-05-2017)“…The potential of human fetal bone cells for successful bone regeneration has been shown in vivo. In particular, it has been demonstrated that the seeding of…”
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17
Activities of daily living with reverse prostheses: importance of scapular compensation for functional mobility of the shoulder
Published in Journal of shoulder and elbow surgery (01-07-2013)“…Hypothesis The nonanatomical design of reverse shoulder prostheses induce medial displacement of the center of rotation, impingements and may reduce the…”
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18
Thoughts on cartilage tissue engineering: A 21st century perspective
Published in Current research in translational medicine (01-07-2021)“…In mature individuals, hyaline cartilage demonstrates a poor intrinsic capacity for repair, thus even minor defects could result in progressive degeneration,…”
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In vitro Implementation of Photopolymerizable Hydrogels as a Potential Treatment of Intracranial Aneurysms
Published in Frontiers in bioengineering and biotechnology (03-04-2020)“…Intracranial aneurysms are increasingly being treated with endovascular therapy, namely coil embolization. Despite being minimally invasive, partial occlusion…”
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Pulsatile Flow-Induced Fatigue-Resistant Photopolymerizable Hydrogels for the Treatment of Intracranial Aneurysms
Published in Frontiers in bioengineering and biotechnology (20-01-2021)“…An alternative intracranial aneurysm embolic agent is emerging in the form of hydrogels due to their ability to be injected in liquid phase and solidify …”
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