Search Results - "Pioletti, Dominique"

Thoughts on cartilage tissue engineering: A 21st century perspective by Stampoultzis, Theofanis, Karami, Peyman, Pioletti, Dominique P.

“…In mature individuals, hyaline cartilage demonstrates a poor intrinsic capacity for repair, thus even minor defects could result in progressive degeneration,…”
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Control of Dissipation Sources: A Central Aspect for Enhancing the Mechanical and Mechanobiological Performances of Hydrogels by Nasrollahzadeh, Naser, Karami, Peyman, Pioletti, Dominique P

“…Development of mechanically durable and biologically inductive hydrogels is a major challenge for load-bearing applications such as engineered cartilage…”
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Impact of Molecular Dynamics of Polyrotaxanes on Chondrocytes in Double-Network Supramolecular Hydrogels under Physiological Thermomechanical Stimulation by Stampoultzis, Theofanis, Rana, Vijay Kumar, Guo, Yanheng, Pioletti, Dominique P.

“…Hyaline cartilage, a soft tissue enriched with a dynamic extracellular matrix, manifests as a supramolecular system within load-bearing joints. At the same…”
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A guide to preclinical evaluation of hydrogel-based devices for treatment of cartilage lesions by Karami, Peyman, Stampoultzis, Theofanis, Guo, Yanheng, Pioletti, Dominique P.

“…The drive to develop cartilage implants for the treatment of major defects in the musculoskeletal system has resulted in a major research thrust towards…”
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NIR Light-Mediated Photocuring of Adhesive Hydrogels for Noninvasive Tissue Repair via Upconversion Optogenesis by Karami, Peyman, Rana, Vijay Kumar, Zhang, Qianyi, Boniface, Antoine, Guo, Yanheng, Moser, Christophe, Pioletti, Dominique P.

“…The surgical treatments of injured soft tissues lead to further injury due to the use of sutures or the surgical routes, which need to be large enough to…”
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Composite Double-Network Hydrogels To Improve Adhesion on Biological Surfaces by Karami, Peyman, Wyss, Céline Samira, Khoushabi, Azadeh, Schmocker, Andreas, Broome, Martin, Moser, Christophe, Bourban, Pierre-Etienne, Pioletti, Dominique P

“…Despite the development of hydrogels with high mechanical properties, insufficient adhesion between these materials and biological surfaces significantly…”
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Glenohumeral joint force prediction with deep learning by Eghbali, Pezhman, Becce, Fabio, Goetti, Patrick, Büchler, Philippe, Pioletti, Dominique P., Terrier, Alexandre

“…Deep learning models (DLM) are efficient replacements for computationally intensive optimization techniques. Musculoskeletal models (MSM) typically involve…”
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Cartilage Repair: Promise of Adhesive Orthopedic Hydrogels by Karami, Peyman, Laurent, Alexis, Philippe, Virginie, Applegate, Lee Ann, Pioletti, Dominique P, Martin, Robin

“…Cartilage repair remains a major challenge in human orthopedic medicine, necessitating the application of innovative strategies to overcome existing technical…”
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HSP70—A key regulator in chondrocyte homeostasis under naturally coupled hydrostatic pressure-thermal stimuli by Guo, Yanheng, Stampoultzis, Theofanis, Karami, Peyman, Nasrollahzadeh, Naser, Rana, Vijay K., Pioletti, Dominique P.

“…During physical activities, chondrocytes experience coupled stimulation of hydrostatic pressure (HP) and a transient increase in temperature (T), with the…”
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An Intrinsically‐Adhesive Family of Injectable and Photo‐Curable Hydrogels with Functional Physicochemical Performance for Regenerative Medicine by Karami, Peyman, Nasrollahzadeh, Naser, Wyss, Céline, O'Sullivan, Aine, Broome, Martin, Procter, Philip, Bourban, Pierre‐Etienne, Moser, Christophe, Pioletti, Dominique P.

“…Attaching hydrogels to soft internal tissues is crucial for the development of various biomedical devices. Tough sticky hydrogel patches present high adhesion,…”
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A photopolymerized composite hydrogel and surgical implanting tool for a nucleus pulposus replacement by Schmocker, Andreas, Khoushabi, Azadeh, Frauchiger, Daniela A, Gantenbein, Benjamin, Schizas, Constantin, Moser, Christophe, Bourban, Pierre-Etienne, Pioletti, Dominique P

“…Abstract Nucleus pulposus replacements have been subjected to highly controversial discussions over the last 40 years. Their use has not yet resulted in a…”
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Enhancing Robustness of Adhesive Hydrogels through PEG-NHS Incorporation by Uslu, Ece, Rana, Vijay Kumar, Guo, Yanheng, Stampoultzis, Theofanis, Gorostidi, François, Sandu, Kishore, Pioletti, Dominique P.

“…Tissue wounds are a significant challenge for the healthcare system, affecting millions globally. Current methods like suturing and stapling have limitations…”
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Experimental method to characterize the strain dependent permeability of tissue engineering scaffolds by Nasrollahzadeh, Naser, Pioletti, Dominique P

“…Abstract Permeability is an overarching mechanical parameter encompassing the effects of porosity, pore size, and interconnectivity of porous structures. This…”
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Biodegradable HEMA-based hydrogels with enhanced mechanical properties by Moghadam, Mohamadreza Nassajian, Pioletti, Dominique P.

“…Hydrogels are widely used in the biomedical field. Their main purposes are either to deliver biological active agents or to temporarily fill a defect until…”
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Effects of glenoid inclination and acromion index on humeral head translation and glenoid articular cartilage strain by Engelhardt, Christoph, PhD, Farron, Alain, MD, Becce, Fabio, MD, Place, Nicolas, PhD, Pioletti, Dominique P., PhD, Terrier, Alexandre, PhD

“…Background Previous clinical studies have reported associations between glenoid inclination (GI), the acromion index (AI), and the critical shoulder angle…”
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A Matlab toolbox for scaled-generic modeling of shoulder and elbow by Sarshari, Ehsan, Boulanaache, Yasmine, Terrier, Alexandre, Farron, Alain, Mullhaupt, Philippe, Pioletti, Dominique

“…There still remains a barrier ahead of widespread clinical applications of upper extremity musculoskeletal models. This study is a step toward lifting this…”
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In vitro and in vivo investigation of bisphosphonate‐loaded hydroxyapatite particles for peri‐implant bone augmentation by Kettenberger, Ulrike, Luginbuehl, Vera, Procter, Philip, Pioletti, Dominique P.

“…Locally applied bisphosphonates, such as zoledronate, have been shown in several studies to inhibit peri‐implant bone resorption and recently to enhance…”
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Strategies for improving the repair of focal cartilage defects by Abdel-Sayed, Philippe, Pioletti, Dominique P

“…Articular cartilage, together with skin, was predicted to be one of the first tissues to be successfully engineered. However cartilage repair remains nowadays…”
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Design of Customized Mouthguards with Superior Protection Using Digital-Based Technologies and Impact Tests by Nasrollahzadeh, Naser, Pioletti, Dominique P., Broome, Martin

“…Background In contact sports, an impact on the jaw can generate destructive stress on the tooth-bone system. Mouthguards can be beneficial in reducing the…”
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Mimicking Loading-Induced Cartilage Self-Heating in Vitro Promotes Matrix Formation in Chondrocyte-Laden Constructs with Different Mechanical Properties by Stampoultzis, Theofanis, Guo, Yanheng, Nasrollahzadeh, Naser, Karami, Peyman, Pioletti, Dominique P.

“…Articular cartilage presents a mechanically sensitive tissue. Chondrocytes, the sole cell type residing in the tissue, perceive and react to physical cues as…”
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