Search Results - "Pinzone, Joseph J."
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The role of Dickkopf-1 in bone development, homeostasis, and disease
Published in Blood (15-01-2009)“…Wnt/β-catenin signaling is central to bone development and homeostasis in adulthood and its deregulation is associated with bone pathologies. Dickkopf-1…”
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Estimated number of prevalent cases of metastatic bone disease in the US adult population
Published in Clinical epidemiology (2012)“…The prevalence of metastatic bone disease in the US population is not well understood. We sought to estimate the current number of US adults with metastatic…”
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Dickkopf-1 (DKK-1) stimulated prostate cancer growth and metastasis and inhibited bone formation in osteoblastic bone metastases
Published in The Prostate (01-05-2011)“…BACKGROUND Osteoblastic bone metastasis is the predominant phenotype observed in prostate cancer patients and is associated with high patient mortality and…”
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Effects of Thiazolidinediones on Differentiation, Proliferation, and Apoptosis
Published in Molecular cancer research (01-06-2007)“…Thiazolidinediones induce adipocyte differentiation and thereby limit proliferative potential; hence, early investigations focused on their ability to modulate…”
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Thiazolidinediones Downregulate Wnt/β-Catenin Signaling Via Multiple Mechanisms in Breast Cancer Cells
Published in The Journal of surgical research (15-05-2009)“…Background Thiazolidinediones (TZDs) have been demonstrated to possess antitumor effects in breast cancer cells, although the mechanisms are not well…”
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Troglitazone inhibits cell migration, adhesion, and spreading by modulating cytoskeletal rearrangement in human breast cancer cells
Published in Molecular carcinogenesis (01-12-2008)“…Metastatic tumors are the primary cause of death in patients with breast cancer. Recent data indicate that the peroxisome proliferator‐activated receptor γ…”
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Rosiglitazone sensitizes MDA-MB-231 breast cancer cells to anti-tumour effects of tumour necrosis factor-α, CH11 and CYC202
Published in Endocrine-related cancer (01-06-2007)“…Peroxisome proliferator-activated receptor-γ (PPARγ) is a member of the nuclear hormone superfamily and has multiple endogenous and pharmacological ligands,…”
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Molecular and Cellular Determinants of Estrogen Receptor α Expression
Published in Molecular and cellular biology (01-06-2004)Get full text
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Hepatic artery chemoembolization in 122 patients with metastatic carcinoid tumor: lessons learned
Published in Journal of gastrointestinal surgery (01-03-2007)“…Hepatic artery chemoembolization (HACE) is a treatment option in the management of metastatic carcinoid. We reviewed our experience to identify potential…”
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Beta protein 1 homeoprotein induces cell growth and estrogen-independent tumorigenesis by binding to the estrogen receptor in breast cancer
Published in Oncotarget (16-08-2016)“…Expression of Beta Protein 1 (BP1), a homeotic transcription factor, increases during breast cancer progression and may be associated with tumor…”
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Zoledronic acid decreased osteolysis but not bone metastasis in a nude mouse model of canine prostate cancer with mixed bone lesions
Published in The Prostate (01-07-2008)“…BACKGROUND Bone metastasis is the most common cause of morbidity and mortality in patients with advanced prostate cancer and is manifested primarily as mixed…”
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Primary medical therapy of micro- and macroprolactinomas in men
Published in The journal of clinical endocrinology and metabolism (01-09-2000)“…The presentation and long-term therapeutic responses of PRL-secreting pituitary tumors in men have been only partially studied. Gender-specific differences in…”
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Peroxisome proliferator-activated receptor gamma-independent repression of prostate-specific antigen expression by thiazolidinediones in prostate cancer cells
Published in Molecular pharmacology (01-05-2006)“…In light of the potential use of the thiazolidinedione family of peroxisome proliferator-activated receptor-gamma (PPARgamma) agonists in prostate cancer…”
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Expression of BP1, a novel homeobox gene, correlates with breast cancer progression and invasion
Published in Breast cancer research and treatment (01-04-2005)“…Our previous studies revealed that the mRNA encoded by BP1, a member of the homeobox gene superfamily of transcription factors, was expressed in leukemia and…”
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BP1 transcriptionally activates bcl-2 and inhibits TNFα-induced cell death in MCF7 breast cancer cells
Published in Breast cancer research : BCR (01-01-2007)“…Introduction We have previously shown that the Beta Protein 1 (BP1) homeodomain protein is expressed in 81% of invasive ductal breast carcinomas, and that…”
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Correlation of expression of BP1, a homeobox gene, with estrogen receptor status in breast cancer
Published in Breast cancer research : BCR (01-01-2003)“…BP1 is a novel homeobox gene cloned in our laboratory. Our previous studies in leukemia demonstrated that BP1 has oncogenic properties, including as a…”
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BP1 transcriptionally activates bcl-2and inhibits TNFα-induced cell death in MCF7 breast cancer cells
Published in Breast cancer research : BCR (13-09-2007)Get full text
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BP1 transcriptionally activates bcl-2and inhibits TNF[alpha]-induced cell death in MCF7 breast cancer cells
Published in Breast cancer research : BCR (13-09-2007)“…Introduction We have previously shown that the Beta Protein 1 (BP1) homeodomain protein is expressed in 81% of invasive ductal breast carcinomas, and that…”
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