Search Results - "Pinzon Arteaga, Carlos A."
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Derivation of Intermediate Pluripotent Stem Cells Amenable to Primordial Germ Cell Specification
Published in Cell stem cell (04-03-2021)“…Dynamic pluripotent stem cell (PSC) states are in vitro adaptations of pluripotency continuum in vivo. Previous studies have generated a number of PSCs with…”
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Modeling post-implantation stages of human development into early organogenesis with stem-cell-derived peri-gastruloids
Published in Cell (31-08-2023)“…In vitro stem cell models that replicate human gastrulation have been generated, but they lack the essential extraembryonic cells needed for embryonic…”
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Derivation and Primordial Germ Cell Induction of Intermediate Pluripotent Stem Cells
Published in Methods in molecular biology (Clifton, N.J.) (2023)“…Dynamic pluripotent stem cell (PSC) states are in vitro adaptations of the pluripotency continuum in vivo. Previous studies have generated a number of PSCs…”
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Cell competition constitutes a barrier for interspecies chimerism
Published in Nature (London) (08-04-2021)“…Cell competition involves a conserved fitness-sensing process during which fitter cells eliminate neighbouring less-fit but viable cells 1 . Cell competition…”
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Generation of Human Blastoids from Naive Pluripotent Stem Cells
Published in Methods in molecular biology (Clifton, N.J.) (2024)“…Under certain culture conditions, naive human pluripotent stem cells can generate human blastocyst-like structures (called human blastoids). Human blastoids…”
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Establishment of bovine trophoblast stem cells
Published in Cell reports (Cambridge) (30-05-2023)“…Here, we report that a chemical cocktail (LCDM: leukemia inhibitory factor [LIF], CHIR99021, dimethinedene maleate [DiM], minocycline hydrochloride),…”
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Large-scale production of human blastoids amenable to modeling blastocyst development and maternal-fetal cross talk
Published in Cell stem cell (07-09-2023)“…Recent advances in human blastoids have opened new avenues for modeling early human development and implantation. One limitation of our first protocol for…”
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TASOR expression in naive embryonic stem cells safeguards their developmental potential
Published in Cell reports (Cambridge) (26-11-2024)“…The seamless transition through stages of pluripotency relies on a balance between transcription factor networks and epigenetic mechanisms. Here, we reveal the…”
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Bovine blastocyst-like structures derived from stem cell cultures
Published in Cell stem cell (04-05-2023)“…Understanding the mechanisms of blastocyst formation and implantation is critical for improving farm animal reproduction but is hampered by a limited supply of…”
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