Search Results - "Pinto, YM"

QT lengthening and life-threatening arrhythmias associated with fexofenadine by Pinto, YM, van Gelder, IC, Heeringa, M, Crijns, HJGM

“…For clinicians treating patients with suspected or known QTc prolongation and ventricular arrhythmias, it is important to be aware of rare but life-threatening…”
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N-Acetyl-Ser-Asp-Lys-Pro Inhibits Phosphorylation of Smad2 in Cardiac Fibroblasts by Pokharel, Saraswati, Rasoul, Saman, Roks, Anton J.M, van Leeuwen, Rick E.W, van Luyn, Marja J.A, Deelman, Leo E, Smits, Jos F, Carretero, Oscar, van Gilst, Wiek H, Pinto, Yigal M

“…N-Acetyl-Ser-Asp-Lys-Pro (AcSDKP) is a specific substrate for the N-terminal site of ACE and increases 5-fold during ACE inhibitor therapy. It is known to…”
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Current state of knowledge on aetiology, diagnosis, management, and therapy of myocarditis: a position statement of the European Society of Cardiology Working Group on Myocardial and Pericardial Diseases by Caforio, Alida L P, Pankuweit, Sabine, Arbustini, Eloisa, Basso, Cristina, Gimeno-Blanes, Juan, Felix, Stephan B, Fu, Michael, Heliö, Tiina, Heymans, Stephane, Jahns, Roland, Klingel, Karin, Linhart, Ales, Maisch, Bernhard, McKenna, William, Mogensen, Jens, Pinto, Yigal M, Ristic, Arsen, Schultheiss, Heinz-Peter, Seggewiss, Hubert, Tavazzi, Luigi, Thiene, Gaetano, Yilmaz, Ali, Charron, Philippe, Elliott, Perry M

“…In this position statement of the ESC Working Group on Myocardial and Pericardial Diseases an expert consensus group reviews the current knowledge on clinical…”
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RBM20 Mutations Induce an Arrhythmogenic Dilated Cardiomyopathy Related to Disturbed Calcium Handling by van den Hoogenhof, Maarten M.G, Beqqali, Abdelaziz, Amin, Ahmad S, van der Made, Ingeborg, Aufiero, Simona, Khan, Mohsin A.F, Schumacher, Cees A, Jansweijer, Joeri A, van Spaendonck-Zwarts, Karin Y, Remme, Carol Ann, Backs, Johannes, Verkerk, Arie O, Baartscheer, Antonius, Pinto, Yigal M, Creemers, Esther E

“…BACKGROUND:Mutations in RBM20 (RNA-binding motif protein 20) cause a clinically aggressive form of dilated cardiomyopathy, with an increased risk of malignant…”
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NT-proBNP testing for diagnosis and short-term prognosis in acute destabilized heart failure: an international pooled analysis of 1256 patients by Januzzi, James L., van Kimmenade, Roland, Lainchbury, John, Bayes-Genis, Antoni, Ordonez-Llanos, Jordi, Santalo-Bel, Miguel, Pinto, Yigal M., Richards, Mark

“…Aims Experience with amino-terminal pro-brain natriuretic peptide (NT-proBNP) testing for evaluation of dyspnoeic patients with suspected acute heart failure…”
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Primary Prevention of Sudden Death in Patients with Lamin A/C Gene Mutations by Pinto, Yigal M, Duboc, Denis, Bonne, Gisèle, Van Berlo, Jop H, Meune, Christophe, Anselme, Frédéric

“…To the Editor: Lamin A/C gene mutations are associated with various disorders, 1 , 2 including cardiac abnormalities characterized by atrial fibrillation,…”
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Which heart failure patients profit from natriuretic peptide guided therapy? A meta-analysis from individual patient data of randomized trials by Brunner-La Rocca, Hans-Peter, Eurlings, Luc, Richards, A. Mark, Januzzi, James L., Pfisterer, Matthias E., Dahlström, Ulf, Pinto, Yigal M., Karlström, Patric, Erntell, Hans, Berger, Rudolf, Persson, Hans, O'Connor, Christopher M., Moertl, Deddo, Gaggin, Hanna K., Frampton, Christopher M., Nicholls, M. Gary, Troughton, Richard W.

“…Aims Previous analyses suggest that heart failure (HF) therapy guided by (N‐terminal pro‐)brain natriuretic peptide (NT‐proBNP) might be dependent on left…”
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Electrocardiogram-based mortality prediction in patients with COVID-19 using machine learning by Bleijendaal, H, Van Der Leur, RR, Taha, K, Mast, T, Gho, JMIH, Winter, MM, Zwinderman, AH, Doevendans, PA, Pinto, YM, Asselbergs, FW, Van Es, R, Tjong, FVY

“…Abstract Funding Acknowledgements Type of funding sources: Public hospital(s). Main funding source(s): The Netherlands Organisation for Health Research and…”
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Post corona infection cardiac abnormalities and the risk for sudden cardiac death by Van Hattum, J, Spies, JL, Verwijs, SM, Verwoert, GC, Boekholdt, SM, Groenink, M, Pinto, YM, Wilde, AAM, Jorstad, HT

“…Abstract Funding Acknowledgements Type of funding sources: Other. Main funding source(s): Dutch Olympic Committee*Dutch Sports Federation (NOC*NSF) Amsterdam…”
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Galectin-3 marks activated macrophages in failure-prone hypertrophied hearts and contributes to cardiac dysfunction by Sharma, Umesh C, Pokharel, Saraswati, van Brakel, Thomas J, van Berlo, Jop H, Cleutjens, Jack P M, Schroen, Blanche, André, Sabine, Crijns, Harry J G M, Gabius, Hans-J, Maessen, Jos, Pinto, Yigal M

“…Inflammatory mechanisms have been proposed to be important in heart failure (HF), and cytokines have been implicated to add to the progression of HF. However,…”
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Late gadolinium enhancement of the hinge point is a common finding in asymptomatic ELITE athletes by Verwijs, SM, Van Hattum, JC, Spies, JL, Boekholdt, SM, Planken, RN, Groenink, M, Van Randen, A, Van Luijk, RD, Van Den Berg-Faaij, AM, Bakermans, AJ, Nederveen, AJ, Moen, MH, Pinto, YM, Wilde, AAM, Jorstad, HT

“…Abstract Funding Acknowledgements Type of funding sources: None. Background Late gadolinium enhancement (LGE) demonstrates regional differences in myocardial…”
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SARS-CoV-2 associated cardiac abnormalities in elite athletes: results from the prospective, longitudinal COMMIT cohort by Van Hattum, J, Verwijs, SM, Davelaar, SE, Daems, JJN, Boekholdt, SM, Groenink, M, Planken, RN, Van Luijk-Snoeks, RD, Van Den Berg-Faay, AM, Moen, MH, Wijne, CACM, Nederveen, AJ, Pinto, YM, Wilde, AAM, Jorstad, HT

“…Abstract Funding Acknowledgements Type of funding sources: Other. Main funding source(s): Dutch National Olympic Committee & National Sports Federation…”
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Aortic dilatation using cardiac magnetic resonance in asymptomatic ELITE athletes by Verwijs, SM, Van Hattum, JC, Stomilovic, N, Daems, JJN, Boekholdt, SM, Planken, RN, Groenink, M, Van Randen, A, Bakermans, AJ, Nederveen, AJ, Moen, MH, Pinto, YM, Wilde, AAM, Jorstad, HT

“…Abstract Funding Acknowledgements Type of funding sources: None. Purpose Aortic dilatation is associated with acute aortic pathology. Cardiac magnetic…”
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The sports cardiology team: personalising athlete care through a comprehensive, multidisciplinary approach by Van Hattum, J, Verwijs, SM, De Vries, ST, Boekholdt, SM, Groenink, M, Van Randen, A, Panhuyzen-Goedkoop, NM, Willems, AR, Knobbe, I, Blom, NA, Van Der Crabben, SN, Bijsterveld, NR, Pinto, YM, Wilde, AAM, Jorstad, HT

“…Abstract Funding Acknowledgements Type of funding sources: Other. Main funding source(s): Dutch National Olympic Committee & National Sports Federation…”
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Normalization of global longitudinal strain after 20 squats in elite athletes by Bruin De- Bon, H, Verwijs, SM, Hattum Van, JC, Blomjous, AGA, Planken, RN, Boekholdt, SM, Groenink, M, Hoogenband Van Den, CR, Moen, MH, Wilde, AAM, Pinto, YM, Bouma, BJ, Jorstad, HT

“…Abstract Funding Acknowledgements Type of funding sources: None. Background/Introduction: Transthoracic echocardiography (TTE) is often the first diagnostic…”
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Increased cardiac expression of tissue inhibitor of metalloproteinase-1 and tissue inhibitor of metalloproteinase-2 is related to cardiac fibrosis and dysfunction in the chronic pressure-overloaded human heart by HEYMANS, Stephane, SCHROEN, Blanche, VAN DE WERF, Frans, PINTO, Yigal M, JANSSENS, Stefan, VERMEERSCH, Pieter, MILTING, Hendrik, GAO, Fangye, KASSNER, Astrid, GILLIJNS, Hilde, HERIJGERS, Paul, FLAMENG, Willem, CARMELIET, Peter

“…Alterations in the balance of matrix metalloproteinases (MMPs) and their specific tissue inhibitors (TIMPs) are involved in left ventricular (LV) remodeling…”
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Matricellular proteins in the heart: possible role during stress and remodeling by SCHELLINGS, Mark W. M, PINTO, Yigal M, HEYMANS, Stephane

“…Matricellular proteins are extracellular matrix proteins that modulate cell-matrix interactions and cell function, and do not seem to have a direct structural…”
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Suppression of gene silencing: a general strategy used by diverse DNA and RNA viruses of plants by Voinnet, O, Pinto, Y.M, Baulcombe, D.C

“…In transgenic and nontransgenic plants, viruses are both initiators and targets of a defense mechanism that is similar to posttranscriptional gene silencing…”
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Meta-analysis of clinical characteristics of 299 carriers of LMNA gene mutations: do lamin A/C mutations portend a high risk of sudden death? by van Berlo, Jop H, de Voogt, Willem G, van der Kooi, Anneke J, van Tintelen, J Peter, Bonne, Gisèle, Yaou, Rabah Ben, Duboc, Denis, Rossenbacker, Tom, Heidbüchel, Hein, de Visser, Marianne, Crijns, Harry J G M, Pinto, Yigal M

“…This study evaluated common clinical characteristics of patients with lamin A/C gene mutations that cause either isolated dilated cardiomyopathy or dilated…”
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A-type lamins are essential for TGF- beta 1 induced PP2A to dephosphorylate transcription factors by Van Berlo, JH, Voncken, J W, Kubben, N, Broers, JLV, Duisters, R, van Leeuwen, REW, Crijns, HJGM, Ramaekers, FCS, Hutchison, C J, Pinto, Y M

“…Diseases caused by mutations in lamins A and C (laminopathies) suggest a crucial role for A-type lamins in different cellular processes. Laminopathies mostly…”
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