Search Results - "Pinto, Ruxandra L"

Non-inferiority trial of a shorter (7 days) compared with a longer (14 days) duration of antimicrobial therapy for the treatment of bacteraemic urinary sepsis, measured by microbiological success after the completion of therapy: a substudy protocol for the Bacteraemia Antibiotic Length Actually Needed for Clinical Effectiveness (BALANCE) multicentre randomised controlled trial by Rogers, Benjamin A, Fowler, Robert, Harris, Patrick N A, Davis, Joshua S, Pinto, Ruxandra L, Bhatia Dwivedi, Dhiraj, Rishu, Asgar, Shehabi, Yahya, Daneman, Nick

“…IntroductionThe BALANCE study is a randomised clinical trial (3626 participants) designed to assess the non-inferiority of 7 days (short-course) antibiotic…”
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Evaluating the impact of a SIMPlified LaYered consent process on recruitment of potential participants to the Staphylococcus aureus Network Adaptive Platform trial: study protocol for a multicentre pragmatic nested randomised clinical trial (SIMPLY-SNAP trial) by Ong, Sean W X, Lee, Todd C, Fowler, Robert A, Mahar, Robert, Pinto, Ruxandra L, Rishu, Asgar, Petrella, Lina, Whiteway, Lyn, Cheng, Matthew, McDonald, Emily, Johnstone, Jennie, Mertz, Dominik, Kandel, Christopher, Somayaji, Ranjani, Davis, Joshua S, Tong, Steven Y C, Daneman, Nick

“…IntroductionInformed consent forms (ICFs) for randomised clinical trials (RCTs) can be onerous and lengthy. The process has the potential to overwhelm patients…”
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Bacteremia Antibiotic Length Actually Needed for Clinical Effectiveness (BALANCE) randomised clinical trial: study protocol by Daneman, Nick, Rishu, Asgar H, Pinto, Ruxandra L, Arabi, Yaseen M, Cook, Deborah J, Hall, Richard, McGuinness, Shay, Muscedere, John, Parke, Rachael, Reynolds, Steven, Rogers, Benjamin, Shehabi, Yahya, Fowler, Robert A

“…IntroductionBloodstream infections are a leading cause of mortality and morbidity; the duration of treatment for these infections is understudied.Methods and…”
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Long-Term Outcomes and Health Care Utilization after Prolonged Mechanical Ventilation by Hill, Andrea D, Fowler, Robert A, Burns, Karen E A, Rose, Louise, Pinto, Ruxandra L, Scales, Damon C

“…Limited data are available to characterize the long-term outcomes and associated costs for patients who require prolonged mechanical ventilation (PMV; defined…”
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Airway Management Strategies for Brain-injured Patients Meeting Standard Criteria to Consider Extubation. A Prospective Cohort Study by McCredie, Victoria A, Ferguson, Niall D, Pinto, Ruxandra L, Adhikari, Neill K J, Fowler, Robert A, Chapman, Martin G, Burrell, Althea, Baker, Andrew J, Cook, Deborah J, Meade, Maureen O, Scales, Damon C

“…Patients with acute brain injury are frequently capable of breathing spontaneously with minimal ventilatory support despite persistent neurological impairment…”
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Closed loop communication in the trauma bay: identifying opportunities for team performance improvement through a video review analysis by Bhangu, Avneesh, Notario, Lowyl, Pinto, Ruxandra L, Pannell, Dylan, Thomas-Boaz, Will, Freedman, Corey, Tien, Homer, Nathens, Avery B, da Luz, Luis

“…Communication among trauma team members in the trauma bay is vulnerable to errors, which may impact patient outcomes. We used the previously validated…”
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A study protocol for an observational cohort investigating COGnitive outcomes and WELLness in survivors of critical illness: the COGWELL study by Wilcox, M Elizabeth, Lim, Andrew S, McAndrews, Mary P, Wennberg, Richard A, Pinto, Ruxandra L, Black, Sandra E, Walczak, Karolina D, Friedrich, Jan O, Taglione, Michael S, Rubenfeld, Gordon D

“…IntroductionUp to 9 out of 10 intensive care unit (ICU) survivors will suffer some degree of cognitive impairment at hospital discharge and approximately half…”
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Intravenous Vitamin C in Adults with Sepsis in the Intensive Care Unit by Lamontagne, François, Masse, Marie-Hélène, Menard, Julie, Sprague, Sheila, Pinto, Ruxandra, Heyland, Daren K., Cook, Deborah J, Battista, Marie-Claude, Day, Andrew G., Guyatt, Gordon H., Kanji, Salmaan, Parke, Rachael, McGuinness, Shay P., Tirupakuzhi Vijayaraghavan, Bharath-Kumar, Annane, Djillali, Cohen, Dian, Arabi, Yaseen M., Bolduc, Brigitte, Marinoff, Nicole, Rochwerg, Bram, Millen, Tina, Meade, Maureen O., Hand, Lori, Watpool, Irene, Porteous, Rebecca, Young, Paul J., D’Aragon, Frederick, Belley-Cote, Emilie P., Carbonneau, Elaine, Clarke, France, Maslove, David M., Hunt, Miranda, Chassé, Michaël, Lebrasseur, Martine, Lauzier, François, Mehta, Sangeeta, Quiroz-Martinez, Hector, Rewa, Oleksa G., Charbonney, Emmanuel, Seely, Andrew J.E., Kutsogiannis, Demetrios J., LeBlanc, Remi, Mekontso-Dessap, Armand, Mele, Tina S., Turgeon, Alexis F., Wood, Gordon, Kohli, Sandeep S., Shahin, Jason, Twardowski, Pawel, Adhikari, Neill K.J.

“…In this trial of intravenous vitamin C in adult patients with sepsis, those who received a vitamin C infusion had a higher risk of death or persistent organ…”
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Lessening Organ dysfunction with VITamin C (LOVIT): protocol for a randomized controlled trial by Masse, Marie-Hélène, Ménard, Julie, Sprague, Sheila, Battista, Marie-Claude, Cook, Deborah J, Guyatt, Gordon H, Heyland, Daren K, Kanji, Salmaan, Pinto, Ruxandra, Day, Andrew G, Cohen, Dian, Annane, Djillali, McGuinness, Shay, Parke, Rachael, Carr, Anitra, Arabi, Yaseen, Vijayaraghavan, Bharath Kumar Tirupakuzhi, D'Aragon, Frédérick, Carbonneau, Élaine, Maslove, David, Hunt, Miranda, Rochwerg, Bram, Millen, Tina, Chassé, Michaël, Lebrasseur, Martine, Archambault, Patrick, Deblois, Estel, Drouin, Christine, Lellouche, François, Lizotte, Patricia, Watpool, Irene, Porteous, Rebecca, Clarke, France, Marinoff, Nicole, Belley-Côté, Émilie, Bolduc, Brigitte, Walker, Scott, Iazzetta, John, Adhikari, Neill K J, Lamontagne, François

“…Sepsis is a health problem of global importance; treatments focus on controlling infection and supporting failing organs. Recent clinical research suggests…”
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