Search Results - "Pinto, Rui M.A"

Glutamine and cystine-enriched diets modulate aquaporins gene expression in the small intestine of piglets by Vieira da Silva, Inês, P Soares, Bárbara, Pimpão, Catarina, M A Pinto, Rui, Costa, Teresa, Freire, João P B, Corrent, Etienne, Chalvon-Demersay, Tristan, Prates, José A M, Lopes, Paula A, Soveral, Graça

“…The regulation of glycerol permeability in the gastrointestinal tract is crucial to control fat deposition, lipolysis and gluconeogenesis. Knowing that the…”
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Docosahexaenoic acid at the sn-2 position of structured triacylglycerols improved n-3 polyunsaturated fatty acid assimilation in tissues of hamsters by Bandarra, Narcisa M., Lopes, Paula A., Martins, Susana V., Ferreira, Júlia, Alfaia, Cristina M., Rolo, Eva A., Correia, Jorge J., Pinto, Rui M.A., Ramos-Bueno, Rebeca P., Batista, Irineu, Prates, José A.M., Guil-Guerrero, José L.

“…In this study, we hypothesized that the incorporation of docosahexaenoic acid (DHA) in tissues will be higher when it is ingested as triacylglycerols (TAG)…”
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Starbon®400-HSO3: A green mesoporous carbonaceous solid acid catalyst for the Ritter reaction by Mesquita, Lígia M.M., Pinto, Rui M.A., Salvador, Jorge A.R., Clark, James H., Budarin, Vitaliy L.

“…The application of the Starbon® Technology in the Ritter reaction to afford vic-N-acylamino-hydroxy compounds, in very high yields, is reported…”
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Serum adipokine profile and fatty acid composition of adipose tissues are affected by conjugated linoleic acid and saturated fat diets in obese Zucker rats by Martins, Susana V., Lopes, Paula A., Alfaia, Cristina M., Rodrigues, Pedro O., Alves, Susana P., Pinto, Rui M. A., Castro, Matilde F., Bessa, Rui J. B., Prates, José A. M.

“…Conjugated linoleic acid (CLA) has been reported as having body fat lowering properties and the ability to modulate the inflammatory system in several models…”
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Contrasting cellularity and fatty acid composition in fat depots from Alentejana and Barrosã bovine breeds fed high and low forage diets by Costa, Ana S H, Lopes, Paula A, Estevão, Marta, Martins, Susana V, Alves, Susana P, Pinto, Rui M A, Pissarra, Hugo, Correia, Jorge J, Pinho, Mário, Fontes, Carlos M G A, Prates, José A M

“…During the finishing phase of bovines, large amounts of subcutaneous and visceral fats are deposited leading to production inefficiencies with major impact on…”
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Hot-melt extrusion in the pharmaceutical industry: toward filing a new drug application by Simões, Marta F., Pinto, Rui M.A., Simões, Sérgio

“…•HME enhances oral absorption of poorly soluble drugs through amorphous dispersions.•A systematic step-by-step approach to the development of HME products is…”
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Artificial neural networks applied to quality-by-design: From formulation development to clinical outcome by Simões, Marta F., Silva, Gabriel, Pinto, Ana C., Fonseca, Marlene, Silva, Nuno E., Pinto, Rui M.A., Simões, Sérgio

“…[Display omitted] Quality-by-Design (QbD) is a methodology used to build quality into products and is characterized by a well-defined roadmap. In this study,…”
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Enhanced solid-state stability of amorphous ibrutinib formulations prepared by hot-melt extrusion by Simões, Marta F., Nogueira, Bernardo A., Tabanez, Andreia M., Fausto, Rui, Pinto, Rui M.A., Simões, Sérgio

“…[Display omitted] One of the applications of Hot-Melt Extrusion (HME) is the stabilization of amorphous drugs through its incorporation into polymeric blends…”
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Five-Stage Approach for a Systematic Screening and Development of Etravirine Amorphous Solid Dispersions by Hot-Melt Extrusion by Simões, Marta F, Pereira, Alexandra, Cardoso, Sara, Cadonau, Stephanie, Werner, Karl, Pinto, Rui M. A, Simões, Sérgio

“…The aim of this study was to develop a fast, effective, and material sparing screening method to design amorphous solid dispersions (ASDs) of etravirine to…”
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Steroidal 5α-reductase and 17α-hydroxylase/17,20-lyase (CYP17) inhibitors useful in the treatment of prostatic diseases by Salvador, Jorge A.R., Pinto, Rui M.A., Silvestre, Samuel M.

“…•Steroidal inhibitors clinically useful in prostatic diseases are reviewed.•5α-Reductase is an enzyme of interest in benign prostatic hyperplasy.•CYP17 enzyme…”
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Medication adherence in older people with rheumatoid arthritis is lower according to electronic monitoring than according to pill count by Hartman, Linda, Cutolo, Maurizio, Bos, Reinhard, Opris-Belinski, Daniela, Kok, Marc R, Griep-Wentink, Hanneke J R M, Klaasen, Ruth, Allaart, Cornelia F, Bruyn, George A W, Raterman, Hennie G, Voshaar, Marieke J H, Gomes, Nuno, Pinto, Rui M A, Klausch, L Thomas, Lems, Willem F, Boers, M

“…Suboptimal medication adherence is a serious problem in the treatment of chronic inflammatory diseases. To measure medication adherence, electronic monitoring…”
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Effect of Laminaria digitata dietary inclusion and CAZyme supplementation on blood cells, serum metabolites and hepatic lipids and minerals of weaned piglets by Ribeiro, David M., Pinto, Rui M. A., Lopes, Paula A., Pestana, José M., Alfaia, Cristina M., Costa, Mónica M., Carvalho, Daniela F. P., Mourato, Miguel P., de Almeida, André M., Freire, João P. B., Prates, José A. M.

“…Seaweeds, such as Laminaria digitata , are a sustainable alternative to conventional feedstuffs for weaned piglet diets, improving their health and mitigating…”
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Dietary Ulva lactuca and CAZyme supplementation improve serum biochemical profile and hepatic composition of weaned piglets by Ribeiro, David M., Lopes, Paula A., Pinto, Rui M. A., Pestana, José M., Costa, Mónica M., Alfaia, Cristina M., Mourato, Miguel P., de Almeida, André M., Freire, João P. B., Prates, José A. M.

“…Ulva lactuca is a seaweed with antinutritional cell wall for monogastrics. Carbohydrate-Active enZymes (CAZymes) supplementation can potentially cause its…”
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Impact of Chlorella vulgaris as feed ingredient and carbohydrases on the health status and hepatic lipid metabolism of finishing pigs by Coelho, Diogo, Alfaia, Cristina M., Lopes, Paula A., Pestana, José M., Costa, Mónica M., Pinto, Rui M.A., Almeida, João M., Moreira, Olga, Fontes, Carlos M.G.A., Prates, José A.M.

“…The implication of high dietary level of Chlorella vulgaris, individually and supplemented with two carbohydrase mixtures, on pigs' health and liver metabolism…”
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Restriction of dietary protein does not promote hepatic lipogenesis in lean or fatty pigs by Madeira, Marta S., Pires, Virgínia M. R., Alfaia, Cristina M., Lopes, Paula A., Martins, Susana V., Pinto, Rui M. A., Prates, José A. M.

“…The influence of genotype (lean v. fatty) and dietary protein level (normal v. reduced) on plasma metabolites, hepatic fatty acid composition and mRNA levels…”
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Betaine and arginine supplementation of low protein diets improves plasma lipids but does not affect hepatic fatty acid composition and related gene expression profiling in pigs by Madeira, Marta S, Rolo, Eva A, Lopes, Paula A, Ramos, Denis A, Alfaia, Cristina M, Pires, Virgínia MR, Martins, Susana V, Pinto, Rui MA, Prates, José AM

“…BACKGROUND The individual and combined effects of betaine and arginine supplemented to reduced protein diets were investigated on plasma metabolites, hepatic…”
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Influence of feeding graded levels of canned sardines on the inflammatory markers and tissue fatty acid composition of Wistar rats by Rodrigues, Pedro O., Martins, Susana V., Lopes, Paula A., Ramos, Cristina, Miguéis, Samuel, Alfaia, Cristina M., Pinto, Rui M. A., Rolo, Eva A., Bispo, Paulo, Batista, Irineu, Bandarra, Narcisa M., Prates, José A. M.

“…Canned sardines are a ready-to-use fish product with excellent nutritional properties owing to its high n-3 long-chain PUFA content, mainly EPA (20 : 5n-3) and…”
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Bismuth(III) salts mediated regioselective ring opening of epoxides: an easy route to halohydrins and β-hydroxy nitrates by Pinto, Rui M.A., Salvador, Jorge A.R., Le Roux, Christophe

“…The ring opening of various epoxides was achieved under mild conditions using bismuth(III) salts. Halohydrins and β-hydroxy nitrates were efficiently obtained…”
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Markers of neuroprotection of combined EPA and DHA provided by fish oil are higher than those of EPA ( Nannochloropsis ) and DHA ( Schizochytrium ) from microalgae oils in Wistar rats by Lopes, Paula A, Bandarra, Narcisa M, Martins, Susana V, Martinho, Joana, Alfaia, Cristina M, Madeira, Marta S, Cardoso, Carlos, Afonso, Cláudia, Paulo, Maria C, Pinto, Rui M A, Guil-Guerrero, José L, Prates, José A M

“…To overcome the current overexploitation of fish rich in 3 long chain polyunsaturated fatty acids (LCPUFA), microalgae have become a promising marine lipid…”
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Impact of high Spirulina diet, extruded or supplemented with enzymes, on blood cells, systemic metabolites, and hepatic lipid and mineral profiles of broiler chickens by Spínola, Maria P, Alfaia, Cristina M, Costa, Mónica M, Pinto, Rui M A, Lopes, Paula A, Pestana, José M, Tavares, João C, Mendes, Ana R, Mourato, Miguel P, Tavares, Beatriz, Carvalho, Daniela F P, Martins, Cátia F, Ferreira, Joana I, Lordelo, Madalena M, Prates, José A M

“…The impact of 15% dietary inclusion of Spirulina ( ) in broiler chickens was explored, focusing on blood cellular components, systemic metabolites and hepatic…”
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