Search Results - "Pinto, Pedro L"

In Vitro and In Vivo Studies of Spironolactone as an Antischistosomal Drug Capable of Clinical Repurposing by Guerra, Rafael A, Silva, Marcos P, Silva, Tais C, Salvadori, Maria C, Teixeira, Fernanda S, de Oliveira, Rosimeire N, Rocha, Jefferson A, Pinto, Pedro L S, de Moraes, Josué

“…Schistosomiasis is a parasitic flatworm disease that infects over 200 million people worldwide, especially in poor communities. Treatment and control of the…”
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Phytol, a diterpene alcohol from chlorophyll, as a drug against neglected tropical disease Schistosomiasis mansoni by de Moraes, Josué, de Oliveira, Rosimeire N, Costa, Jéssica P, Junior, Antonio L G, de Sousa, Damião P, Freitas, Rivelilson M, Allegretti, Silmara M, Pinto, Pedro L S

“…Schistosomiasis is a major endemic disease that affects hundreds of millions worldwide. Since the treatment and control of this parasitic disease rely on a…”
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H1-antihistamines as antischistosomal drugs: in vitro and in vivo studies by Xavier, Rogério P, Mengarda, Ana C, Silva, Marcos P, Roquini, Daniel B, Salvadori, Maria C, Teixeira, Fernanda S, Pinto, Pedro L, Morais, Thiago R, Ferreira, Leonardo L G, Andricopulo, Adriano D, de Moraes, Josué

“…Schistosomiasis is a socioeconomically devastating parasitic infection afflicting hundreds of millions of people and animals worldwide. It is the most…”
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Antischistosomal Activity of Oxindolimine-Metal Complexes by de Moraes, Josué, Dario, Bruno S, Couto, Ricardo A A, Pinto, Pedro L S, da Costa Ferreira, Ana M

“…In recent years, a class of oxindole-copper and -zinc complex derivatives have been reported as compounds with efficient proapoptotic activity toward different…”
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Antiparasitic, structural, pharmacokinetic, and toxicological properties of riparin derivatives by Mafud, Ana C., Silva, Marcos P.N., Nunes, Geandra B.L., de Oliveira, Milene A.R., Batista, Larissa F., Rubio, Thiago I., Mengarda, Ana C., Lago, Eloi M., Xavier, Rogério P., Gutierrez, Stanley J.C., Pinto, Pedro L.S., da Silva Filho, Ademar A., Mascarenhas, Yvonne P., de Moraes, Josué

“…Schistosomiasis, caused by helminth flatworms of the genus Schistosoma, is one of the most important parasitic diseases in the world, affecting over 200…”
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Cyclohexene-fused 1,3-oxazines with selective antibacterial and antiparasitic action and low cytotoxic effects by de Brito, Maria R.M., Peláez, Walter J., Faillace, Martín S., Militão, Gardenia C.G., Almeida, Jackson R.G.S., Argüello, Gustavo A., Szakonyi, Zsolt, Fülöp, Ferenc, Salvadori, Maria C., Teixeira, Fernanda S., Freitas, Rivelilson M., Pinto, Pedro L.S., Mengarda, Ana C., Silva, Marcos P.N., Da Silva Filho, Ademar A., de Moraes, Josué

“…Oxazine derivatives, a class of heterocyclic compounds, exhibit a variety of biological properties, such as anticonvulsant and antitumor activities. In this…”
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Structural parameters, molecular properties, and biological evaluation of some terpenes targeting Schistosoma mansoni parasite by Mafud, Ana C., Silva, Marcos P.N., Monteiro, Daniela C., Oliveira, Maria F., Resende, João G., Coelho, Mayara L., de Sousa, Damião P., Mendonça, Ronaldo Z., Pinto, Pedro L.S., Freitas, Rivelilson M., Mascarenhas, Yvonne P., de Moraes, Josué

“…The use of natural products has a long tradition in medicine, and they have proven to be an important source of lead compounds in the development of new drugs…”
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Anthelmintic, Antibacterial and Cytotoxicity Activity of Imidazole Alkaloids from Pilocarpus microphyllus Leaves by Rocha, Jefferson A., Andrade, Ivanilza M., Véras, Leiz M.C., Quelemes, Patrick V., Lima, David F., Soares, Maria J.S., Pinto, Pedro L.S., Mayo, Simon J., Ivanova, Galya, Rangel, Maria, Correia, Manuela, Mafud, Ana Carolina, Mascarenhas, Yvonne P., Delerue‐Matos, Cristina, Moraes, Josué, Eaton, Peter, Leite, José R.S.A.

“…Pilocarpus microphyllus Stapf ex Wardlew (Rutaceae), popularly known as jaborandi, is a plant native to the northern and northeastern macroregions of Brazil…”
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Anthelmintic activity in vivo of epiisopiloturine against juvenile and adult worms of Schistosoma mansoni by Guimarães, Maria A, de Oliveira, Rosimeire N, Véras, Leiz M C, Lima, David F, Campelo, Yuri D M, Campos, Stefano Augusto, Kuckelhaus, Selma A S, Pinto, Pedro L S, Eaton, Peter, Mafud, Ana C, Mascarenhas, Yvonne P, Allegretti, Silmara M, de Moraes, Josué, Lolić, Aleksandar, Verbić, Tatjana, Leite, José Roberto S A

“…Schistosomiasis is a serious disease currently estimated to affect more that 207 million people worldwide. Due to the intensive use of praziquantel, there is…”
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Antischistosomal activity of the terpene nerolidol by Silva, Marcos P N, Oliveira, George L S, de Carvalho, Rusbene B F, de Sousa, Damião P, Freitas, Rivelilson M, Pinto, Pedro L S, de Moraes, Josué

“…Schistosomiasis is a neglected tropical disease that affects hundreds of millions of people worldwide. Since the treatment of this disease currently relies on…”
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Promethazine Exhibits Antiparasitic Properties In Vitro and Reduces Worm Burden, Egg Production, Hepatomegaly, and Splenomegaly in a Schistosomiasis Animal Model by Roquini, Daniel B, Cogo, Ramon M, Mengarda, Ana C, Mazloum, Susana F, Morais, Cristiane S, Xavier, Rogério P, Salvadori, Maria C, Teixeira, Fernanda S, Ferreira, Luiz E, Pinto, Pedro L, Morais, Thiago R, de Moraes, Josué

“…The treatment and control of schistosomiasis, a neglected disease that affects more than 200 million people worldwide, rely on the use of a single drug,…”
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Antiparasitic activity of nerolidol in a mouse model of schistosomiasis by Silva, Marcos P., de Oliveira, Rosimeire N., Mengarda, Ana C., Roquini, Daniel B., Allegretti, Silmara M., Salvadori, Maria C., Teixeira, Fernanda S., de Sousa, Damião P., Pinto, Pedro L.S., da Silva Filho, Ademar A., de Moraes, Josué

“…•Single oral nerolidol dose resulted in reduction of worm burden in a murine schistosomiasis model.•Oral administration of nerolidol causes reduction in…”
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Phenotypic screening of nonsteroidal anti-inflammatory drugs identified mefenamic acid as a drug for the treatment of schistosomiasis by Lago, Eloi M., Silva, Marcos P., Queiroz, Talita G., Mazloum, Susana F., Rodrigues, Vinícius C., Carnaúba, Paulo U., Pinto, Pedro L., Rocha, Jefferson A., Ferreira, Leonardo L.G., Andricopulo, Adriano D., de Moraes, Josué

“…Treatment and control of schistosomiasis, one of the most insidious and serious parasitic diseases, depend almost entirely on a single drug, praziquantel…”
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Cardamonin, a schistosomicidal chalcone from Piper aduncum L. (Piperaceae) that inhibits Schistosoma mansoni ATP diphosphohydrolase by de Castro, Clarissa C.B., Costa, Poliana S., Laktin, Gisele T., de Carvalho, Paulo H.D., Geraldo, Reinaldo B., de Moraes, Josué, Pinto, Pedro L.S., Couri, Mara R.C., Pinto, Priscila de F., Da Silva Filho, Ademar A.

“…Background: Schistosomiasis is one of the world's major public health problems, and praziquantel (PZQ) is the only available drug to treat this neglected…”
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Garcinielliptone FC: Antiparasitic activity without cytotoxicity to mammalian cells by Silva, Ana P., Silva, Marcos P., Oliveira, Cristiano G., Monteiro, Daniela C., Pinto, Pedro L., Mendonça, Ronaldo Z., Costa Júnior, Joaquim S., Freitas, Rivelilson M., de Moraes, Josué

“…[Display omitted] •Garcinielliptone FC is able to kill Schistosoma mansoni adult worms.•Garcinielliptone FC induced morphological changes on the tegument of…”
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In Vitro and in Vivo Antischistosomal Activities of Chalcones by Pereira, Vinícius R. D., Junior, Ismael J. Alves, da Silveira, Lígia S., Geraldo, Reinaldo B., de F. Pinto, Priscila, Teixeira, Fernanda S., Salvadori, Maria C., Silva, Marcos P., Alves, Lara A., Capriles, Priscila V. S. Z., das C. Almeida, Ayla, Coimbra, Elaine S., Pinto, Pedro L. S., Couri, Mara R. C., de Moraes, Josué, Da Silva Filho, Ademar A.

“…In this study, we evaluated the in vitro and in vivo schistosomicidal activities of chalcones against Schistosoma mansoni worms. In vitro assays revealed that…”
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Schistosomicidal effect of the anti-inflammatory drug diclofenac and its structural correlation with praziquantel by Carvalho, Aline A.L, Mafud, Ana C, Pinto, Pedro L.S, Mascarenhas, Yvonne P, de Moraes, Josué

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Phenotypic screening of nonsteroidal anti-inflammatory drugs identified mefenamic acid as a drug for the treatment of schistosomiasisResearch in context by Eloi M. Lago, Marcos P. Silva, Talita G. Queiroz, Susana F. Mazloum, Vinícius C. Rodrigues, Paulo U. Carnaúba, Pedro L. Pinto, Jefferson A. Rocha, Leonardo L.G. Ferreira, Adriano D. Andricopulo, Josué de Moraes

“…Background: Treatment and control of schistosomiasis, one of the most insidious and serious parasitic diseases, depend almost entirely on a single drug,…”
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Promethazine exhibits antiparasitic properties in vitro and reduces worm burden, egg production, hepato-, and splenomegaly in a schistosomiasis animal model by Roquini, Daniel B, Cogo, Ramon M, Mengarda, Ana C, Mazloum, Susana F, Morais, Cristiane S, Xavier, Rogério P, Salvadori, Maria C, Teixeira, Fernanda S, Ferreira, Luiz E, Pinto, Pedro L, Morais, Thiago R, de Moraes, Josué

“…The treatment and control of schistosomiasis, a neglected disease that affects more than 200 million people worldwide, rely on the use of a single drug,…”
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Simultaneous Occurrence of Acute Myocarditis and Reactivated Chagas' Disease in a Patient with AIDS by Sartori, Ana Marli C., Lopes, Marta H., Caramelli, Bruno, Duarte, Maria Irma S., Pinto, Pedro L. da S., Neto, V. Amato, Shikanai-Yasuda, Maria A.

“…Myocarditis is not an uncommon finding in autopsy series of patients with AIDS, although clinically important myocarditis is rarely noted. We describe a…”
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