Search Results - "Pinto, Nuno"

Wide‐surface pore microfiltration membrane drastically improves sieving decay in TFF‐based perfusion cell culture and streamline chromatography integration for continuous bioprocessing by Pinto, Nuno D. S., Brower, Mark

“…Although several compelling benefits for bioprocess intensification have been reported, the need for a streamlined integration of perfusion cultures with…”
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On-Line Ion Exchange Liquid Chromatography as a Process Analytical Technology for Monoclonal Antibody Characterization in Continuous Bioprocessing by Patel, Bhumit A, Pinto, Nuno D.S, Gospodarek, Adrian, Kilgore, Bruce, Goswami, Kudrat, Napoli, William N, Desai, Jayesh, Heo, Jun H, Panzera, Dominick, Pollard, David, Richardson, Daisy, Brower, Mark, Richardson, Douglas D

“…Combining process analytical technology (PAT) with continuous production provides a powerful tool to observe and control monoclonal antibody (mAb) fermentation…”
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Impact of micro and macroporous TFF membranes on product sieving and chromatography loading for perfusion cell culture by Pinto, Nuno D. S., Napoli, William N., Brower, Mark

“…Bioprocess intensification can be achieved through high cell density perfusion cell culture with continuous protein capture integration. Protein passage and…”
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Evaluation of various membranes at different fluxes to enable large‐volume single‐use perfusion bioreactors by Raza, Hassan, Tang, Tiffany, Gao, Baizhen, Phuangthong, Chelsea, Chen, Chienhung Billy, Pinto, Nuno D. S.

“…The growing demand for biological therapeutics has increased interest in large‐volume perfusion bioreactors, but the operation and scalability of perfusion…”
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Comparison of process mass intensity (PMI) of continuous and batch manufacturing processes for biologics by Madabhushi, Sri R., Pinto, Nuno D S, Lin, Henry

“…Biologics encompasses a wide variety of therapeutics including monoclonal antibodies, fusion proteins, and enzymes, among others. The biologics market is…”
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Improved protein A resin for antibody capture in a continuous countercurrent tangential chromatography system by Fedorenko, Dmitriy, Dutta, Amit K., Tan, Jasmine, Walko, Jonathan, Brower, Mark, Pinto, Nuno D. S., Zydney, Andrew L., Shinkazh, Oleg

“…Continuous countercurrent tangential chromatography (CCTC) enables steady‐state continuous bioprocessing with low‐pressure operation and high productivity…”
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New carvacrol and thymol derivatives as potential insecticides: synthesis, biological activity, computational studies and nanoencapsulation by Natal, Carolina M, Fernandes, Maria José G, Pinto, Nuno F. S, Pereira, Renato B, Vieira, Tatiana F, Rodrigues, Ana Rita O, Pereira, David M, Sousa, Sérgio F, Fortes, A. Gil, Castanheira, Elisabete M. S, Gonçalves, M. Sameiro

“…New compounds with potential insecticide activity were synthesized by structural modifications performed in the monoterpenoid phenolic moieties of carvacrol…”
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Laparoscopic staple line invagination in low colorectal anastomosis – A Video Vignette by Azevedo, Constança, Costa Pereira, Carlos, Vilela Pinto, Nuno, Antunes, Alexandra, Marques, Isabel, Costa Pereira, Joaquim

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Immunoglobulin G elution in protein A chromatography employing the method of chromatofocusing for reducing the co‐elution of impurities by Pinto, Nuno D.S., Uplekar, Shaunak D., Moreira, Antonio R., Rao, Govind, Frey, Douglas D.

“…ABSTRACT Purification processes for monoclonal Immunoglobulin G (IgG) typically employ protein A chromatography as a capture step to remove most of the…”
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Determination of protein concentration in downstream biomanufacturing processes by in‐line index of refraction by Harris, Steven A., Patel, Bhumit A., Gospodarek, Adrian, Desai, Jayesh, Janon Gutiérrez, Alejandro, Botonjic‐Sehic, Edita, Brower, Mark, Pinto, Nuno D. S.

“…Protein concentration determination is a necessary in‐process control for the downstream operations within biomanufacturing. As production transitions from…”
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A Potentially Fatal Cause of Sciatica: A Rare Case of Nerve Compression Caused by a Pseudoaneurysm of the Renal Artery of a Transplanted Kidney by Leal, Andreia, Magalhães, Mariana, Teles Pinto, Nuno

“…Renal transplant is the gold standard treatment for end-stage kidney disease (ESKD). Despite the evolution of renal transplant procedures, complications can…”
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Eugenol β-amino/β-alkoxy alcohols with selective anticancer activity by Teixeira, Cláudia, Pereira, Renato B., Pinto, Nuno F. S., Coelho, Catarina M. M., Fernandes, Maria José G., Fortes, A. Gil, Gonçalves, M. Sameiro T., Pereira, David M.

“…Eugenol, 4-allyl-2-methoxyphenol, is the main constituent of clove essential oil and has demonstrated relevant biological activity, namely anticancer activity…”
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Sulfite concentration and the occurrence of headache in young adults: a prospective study by Silva, Miguel, Gama, Jorge, Pinto, Nuno, Pivi, Glaucia, Brancal, Hugo, Carvalho, Lurdes, Loureiro, Virgílio, Patto, Maria Vaz

“…Background/Objectives Sulfites are additives commonly used in food and wine industries that are associated to adverse clinical effects such as headaches. The…”
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Amino alcohols from eugenol as potential semisynthetic insecticides: chemical, biological, and computational insights by Pereira, Renato B., Pinto, Nuno F. S., Fernandes, Maria José Gomes, Vieira, Tatiana F., Rodrigues, Ana Rita Oliveira, Pereira, David M., Sousa, Sérgio F., Castanheira, Elisabete M. S., Fortes, A. Gil, Gonçalves, M. Sameiro T.

“…A series of β-amino alcohols were prepared by the reaction of eugenol epoxide with aliphatic and aromatic amine nucleophiles. The synthesized compounds were…”
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Fast Serious Analogue Games in Planning: The Role of Non-Player Participants by Sousa, Micael, Antunes, António Pais, Pinto, Nuno, Zagalo, Nelson

“…Objective Public participation has benefited from innovative engagement tools that facilitate the negotiation between diverse sets of stakeholders with…”
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Bilateral theta-burst magnetic stimulation influence on event-related brain potentials by Pinto, Nuno, Duarte, Marta, Gonçalves, Helena, Silva, Ricardo, Gama, Jorge, Pato, Maria Vaz

“…Theta-burst stimulation (TBS) can be a non-invasive technique to modulate cognitive functions, with promising therapeutic potential, but with some…”
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Athlete Health Implications of Match Injuries in Portuguese Rugby Union by Lopes, Nuno Pinto de Sousa, Cruz-Ferreira, António Miguel, Lima, Diana Torres, Silva, Marta Amaral, Santiago, Luiz Miguel

“…Our aim was to report time-loss match injuries in Portugal's "Divisão de Honra" (Portuguese first tier) in the 2022/2023 season, focusing on injury incidence,…”
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A Cellular Automata Model for Integrated Simulation of Land Use and Transport Interactions by Pinto, Nuno, Antunes, António P., Roca, Josep

“…Cellular automata (CA) models have been used in urban studies for dealing with land use change. Transport and accessibility are arguably the main drivers of…”
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Contribution of glial cells to the neuroprotective effects triggered by repetitive magnetic stimulation: a systematic review by Ferreira, Susana, Pinto, Nuno, Serrenho, Inês, Pato, Maria, Baltazar, Graça

“…Repetitive transcranial magnetic stimulation has been increasingly studied in different neurological diseases, and although most studies focus on its effects…”
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Stress profile of urgency/emergency nurses in COVID-19 context: professional determinants by Pinto, Nuno Duarte, Alves, Vitor, Veiga-Branco, Maria Augusta

“…Abstract Introduction: Evidence shows that emergency nurses have developed stress-related health problems in the context of the COVID-19 pandemic. Objectives:…”
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