Search Results - "Pinto, Francisco M."
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The Role of Sperm Membrane Potential and Ion Channels in Regulating Sperm Function
Published in International journal of molecular sciences (01-04-2023)“…During the last seventy years, studies on mammalian sperm cells have demonstrated the essential role of capacitation, hyperactivation and the acrosome reaction…”
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Influence of BMI, Cigarette Smoking and Cryopreservation on Tyrosine Phosphorylation during Sperm Capacitation
Published in International journal of molecular sciences (01-07-2024)“…Capacitation involves tyrosine phosphorylation (TP) as a key marker. Lifestyle-related factors, such as obesity and smoking, are recognized for their adverse…”
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The voltage-gated sodium channel nav1.8 is expressed in human sperm
Published in PloS one (27-09-2013)“…The role of Na(+) fluxes through voltage-gated sodium channels in the regulation of sperm cell function remains poorly understood. Previously, we reported that…”
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Expression and activity profiles of DPP IV/CD26 and NEP/CD10 glycoproteins in the human renal cancer are tumor-type dependent
Published in BMC cancer (11-05-2010)“…Cell-surface glycoproteins play critical roles in cell-to-cell recognition, signal transduction and regulation, thus being crucial in cell proliferation and…”
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Autocrine regulation of human sperm motility by the met-enkephalin opioid peptide
Published in Fertility and sterility (01-09-2012)“…Objective To verify the presence of protein precursor pro-enkephalin (PENK) and met-enkephalin in human spermatozoa and to characterize the effects of…”
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mRNA expression of tachykinins and tachykinin receptors in different human tissues
Published in European journal of pharmacology (28-06-2004)“…The tachykinins substance P, neurokinin A and neurokinin B are involved in many pathophysiological processes. A reverse transcription–polymerase chain reaction…”
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Autocrine regulation of human sperm motility by tachykinins
Published in Reproductive biology and endocrinology (26-08-2010)“…We examined the presence and function of tachykinins and the tachykinin-degrading enzymes neprilysin (NEP) and neprilysin-2 (NEP2) in human spermatozoa…”
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Control of APN/CD13 and NEP/CD10 on sperm motility
Published in Asian journal of andrology (01-11-2010)“…Aminopeptidase N (APN/CD13) and neutral endopeptidase (NEP/CD10) are enzymes present in human sperm cells and involved in regulation of sperm motility of…”
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Airway response to acute mechanical stress in a human bronchial model of stretch
Published in Critical care (London, England) (01-01-2011)“…Lung inflation may have deleterious effects on the alveoli during mechanical ventilation. However, the consequences of stretch during excessive lung inflation…”
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Female infertility is associated with an altered expression of the neurokinin B/neurokinin B receptor and kisspeptin/kisspeptin receptor systems in ovarian granulosa and cumulus cells
Published in Fertility and sterility (01-10-2020)“…To analyze and compare the expression profile of TAC3, TACR3, KISS1, and KISS1R in mural granulosa and cumulus cells from healthy oocyte donors and patients…”
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Ovarian steroids regulate tachykinin and tachykinin receptor gene expression in the mouse uterus
Published in Reproductive biology and endocrinology (23-07-2009)“…In the mouse uterus, pregnancy is accompanied by changes in tachykinin and tachykinin receptor gene expression and in the uterotonic effects of endogenous…”
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Molecular and functional characterization of voltage-gated sodium channels in human sperm
Published in Reproductive biology and endocrinology (16-07-2009)“…We have investigated the expression of voltage-gated sodium channels in human spermatozoa and characterized their role in sperm motility. Freshly ejaculated…”
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13
Functional and Molecular Characterization of Voltage-Gated Sodium Channels in Uteri from Nonpregnant Rats
Published in Biology of reproduction (01-11-2007)“…We investigated the function and expression of voltage-gated Na + channels (VGSC) in the uteri of nonpregnant rats using organ bath techniques, intracellular…”
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Analysis of the expression of neurokinin B, kisspeptin, and their cognate receptors NK3R and KISS1R in the human female genital tract
Published in Fertility and sterility (01-05-2012)“…To investigate the presence of neurokinin B (NKB)/NK3 receptor (NK3R) and kisspeptin/KISS1 receptor (KISS1R) messenger RNA (mRNA) and proteins throughout the…”
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A Role for Tachykinins in Female Mouse and Rat Reproductive Function
Published in Biology of reproduction (01-09-2003)“…Tachykinins may be involved in reproduction. A reverse transcription-polymerase chain reaction assay was used to analyze the expression of tachykinins and…”
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Tachykinins and tachykinin receptors in human uterus
Published in British journal of pharmacology (01-06-2003)“…Studies were undertaken to determine the nature of the receptors mediating contractile effects of tachykinins in the uteri of nonpregnant women, and to analyse…”
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Physical Stress Echocardiography: Prediction of Mortality and Cardiac Events in Patients with Exercise Test showing Ischemia
Published in Arquivos brasileiros de cardiologia (01-11-2014)“…Background: Studies have demonstrated the diagnostic accuracy and prognostic value of physical stress echocardiography in coronary artery disease. However, the…”
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Female Infertility Is Associated with an Altered Expression Profile of Different Members of the Tachykinin Family in Human Granulosa Cells
Published in Reproductive sciences (Thousand Oaks, Calif.) (01-01-2023)“…Neurokinin B (NKB) and its cognate receptor, NK3R, play a key role in the regulation of reproduction. NKB belongs to the family of tachykinins, which also…”
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Regulation of the Stimulant Actions of Neurokinin A and Human Hemokinin-1 on the Human Uterus: A Comparison with Histamine
Published in Biology of reproduction (01-09-2006)“…Regulation of the contractile effects of tachykinins and histamine on the human uterus was investigated with biopsy sections of the outer myometrial layer. The…”
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Altered expression of the kisspeptin/KISS1R and neurokinin B/NK3R systems in mural granulosa and cumulus cells of patients with polycystic ovarian syndrome
Published in Journal of assisted reproduction and genetics (01-01-2019)“…Purpose The neurokinin B (NKB)/NK 3 receptor (NK3R) and kisspeptin (KISS1)/kisspeptin receptor (KISS1R), two systems essential for reproduction, are present in…”
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