Search Results - "Pinto, Catarina I.G."
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Cancer 3D Models for Metallodrug Preclinical Testing
Published in International journal of molecular sciences (25-07-2023)“…Despite being standard tools in research, the application of cellular and animal models in drug development is hindered by several limitations, such as limited…”
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Cobaltabis(dicarbollide) ([ o -COSAN] - ) as Multifunctional Chemotherapeutics: A Prospective Application in Boron Neutron Capture Therapy (BNCT) for Glioblastoma
Published in Cancers (19-12-2021)“…The aim of our study was to assess if the sodium salt of cobaltabis(dicarbollide) and its di-iodinated derivative (Na[ -COSAN] and Na[8,8'-I - -COSAN]) could…”
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Biological properties of a new mixed lanthanide(III) complex incorporating a dypiridinium ylide
Published in Inorganica Chimica Acta (01-06-2020)“…A new mixed Ln(III) complex (La-Nd-DPY) with activity in PC3 cell models. The cytotoxicity is mediated by the generation of reactive oxygen species (ROS). Few…”
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Evaluation of the theranostic potential of [64Cu]CuCl2 in glioblastoma spheroids
Published in EJNMMI research (07-03-2024)“…Background Glioblastoma is an extremely aggressive malignant tumor with a very poor prognosis. Due to the increased proliferation rate of glioblastoma, there…”
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Copper-64 Chloride Exhibits Therapeutic Potential in Three-Dimensional Cellular Models of Prostate Cancer
Published in Frontiers in molecular biosciences (01-12-2020)“…Prostate cancer (PCa) is the second most common cancer type in men, and in advanced metastatic stages is considerable incurable. This justifies the need for…”
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