Search Results - "Pinto, B."

Human lactate dehydrogenase a inhibitors: a molecular dynamics investigation by Shi, Yun, Pinto, B Mario

“…Lactate dehydrogenase A (LDHA) is an important enzyme in fermentative glycolysis, generating most energy for cancer cells that rely on anaerobic respiration…”
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Transcriptome of iPSC-derived neuronal cells reveals a module of co-expressed genes consistently associated with autism spectrum disorder by Griesi-Oliveira, K., Fogo, M. S., Pinto, B. G. G., Alves, A. Y., Suzuki, A. M., Morales, A. G., Ezquina, S., Sosa, O. J., Sutton, G. J., Sunaga-Franze, D. Y., Bueno, A. P., Seabra, G., Sardinha, L., Costa, S. S., Rosenberg, C., Zachi, E. C., Sertie, A. L., Martins-de-Souza, D., Reis, E. M., Voineagu, I., Passos-Bueno, M. R.

“…Evaluation of expression profile in autism spectrum disorder (ASD) patients is an important approach to understand possible similar functional consequences…”
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Prevalence of recurrent pathogenic microdeletions and microduplications in over 9500 pregnancies by Grati, Francesca Romana, Molina Gomes, Denise, Ferreira, Jose Carlos Pinto B., Dupont, Celine, Alesi, Viola, Gouas, Laetitia, Horelli-Kuitunen, Nina, Choy, Kwong Wai, García-Herrero, Sandra, de la Vega, Alberto Gonzalez, Piotrowski, Krzysztof, Genesio, Rita, Queipo, Gloria, Malvestiti, Barbara, Hervé, Bérénice, Benzacken, Brigitte, Novelli, Antonio, Vago, Philippe, Piippo, Kirsi, Leung, Tak Yeung, Maggi, Federico, Quibel, Thibault, Tabet, Anne Claude, Simoni, Giuseppe, Vialard, François

“…Objectives The implementation of chromosomal microarray analysis (CMA) in prenatal testing for all patients has not achieved a consensus. Technical…”
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Effectiveness of Wolbachia-infected mosquito deployments in reducing the incidence of dengue and other Aedes-borne diseases in Niterói, Brazil: A quasi-experimental study by Pinto, Sofia B, Riback, Thais I S, Sylvestre, Gabriel, Costa, Guilherme, Peixoto, Julia, Dias, Fernando B S, Tanamas, Stephanie K, Simmons, Cameron P, Dufault, Suzanne M, Ryan, Peter A, O'Neill, Scott L, Muzzi, Frederico C, Kutcher, Simon, Montgomery, Jacqui, Green, Benjamin R, Smithyman, Ruth, Eppinghaus, Ana, Saraceni, Valeria, Durovni, Betina, Anders, Katherine L, Moreira, Luciano A

“…The introduction of the bacterium Wolbachia (wMel strain) into Aedes aegypti mosquitoes reduces their capacity to transmit dengue and other arboviruses…”
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Naturally Occurring Sulfonium-Ion Glucosidase Inhibitors and Their Derivatives: A Promising Class of Potential Antidiabetic Agents by Mohan, Sankar, Eskandari, Razieh, Pinto, B. Mario

“…In humans, four different enzymes mediate the digestion of ingested carbohydrates. First salivary and pancreatic α-amylases, the two endoacting retaining…”
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H1 histones control the epigenetic landscape by local chromatin compaction by Willcockson, Michael A., Healton, Sean E., Weiss, Cary N., Bartholdy, Boris A., Botbol, Yair, Mishra, Laxmi N., Sidhwani, Dhruv S., Wilson, Tommy J., Pinto, Hugo B., Maron, Maxim I., Skalina, Karin A., Toro, Laura Norwood, Zhao, Jie, Lee, Chul-Hwan, Hou, Harry, Yusufova, Nevin, Meydan, Cem, Osunsade, Adewola, David, Yael, Cesarman, Ethel, Melnick, Ari M., Sidoli, Simone, Garcia, Benjamin A., Edelmann, Winfried, Macian, Fernando, Skoultchi, Arthur I.

“…H1 linker histones are the most abundant chromatin-binding proteins 1 . In vitro studies indicate that their association with chromatin determines nucleosome…”
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Structural Basis for Substrate Selectivity in Human Maltase-Glucoamylase and Sucrase-Isomaltase N-terminal Domains by Sim, Lyann, Willemsma, Carly, Mohan, Sankar, Naim, Hassan Y., Pinto, B. Mario, Rose, David R.

“…Human maltase-glucoamylase (MGAM) and sucrase-isomaltase (SI) are small intestinal enzymes that work concurrently to hydrolyze the mixture of linear α-1,4- and…”
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New Glucosidase Inhibitors from an Ayurvedic Herbal Treatment for Type 2 Diabetes: Structures and Inhibition of Human Intestinal Maltase-Glucoamylase with Compounds from Salacia reticulata by Sim, Lyann, Jayakanthan, Kumarasamy, Mohan, Sankar, Nasi, Ravindranath, Johnston, Blair D, Pinto, B. Mario, Rose, David R

“…An approach to controlling blood glucose levels in individuals with type 2 diabetes is to target α-amylases and intestinal glucosidases using α-glucosidase…”
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Single dose versus multiple dose of antibiotic prophylaxis in caesarean section: a systematic review and meta‐analysis by Pinto‐Lopes, R, Sousa‐Pinto, B, Azevedo, LF

“…Background Prophylactic antibiotics are traditionally given as a single dose for caesarean section. However, inconsistent application of recommendations and…”
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Structural and functional motor cortex asymmetry in unilateral lower limb amputation with phantom limb pain by Pacheco-Barrios, K., Pinto, CB, Saleh Velez, FG, Duarte, D., Gunduz, ME, Simis, M., Lepesteur Gianlorenco, AC, Barouh, JL, Crandell, D., Guidetti, M., Battistella, L., Fregni, F.

“…•There is an asymmetrical reorganization of the motor cortex in patients with phantom limb pain.•We found disorganized and shifted hand cortical representation…”
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Specificity of the Hox member Deformed is determined by transcription factor levels and binding site affinities by Pinto, Pedro B., Domsch, Katrin, Gao, Xuefan, Wölk, Michaela, Carnesecchi, Julie, Lohmann, Ingrid

“…Hox proteins have similar binding specificities in vitro, yet they control different morphologies in vivo. This paradox has been partially solved with the…”
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Do students notice stress in teachers? Associations between classroom teacher burnout and students' perceptions of teacher social–emotional competence by Oberle, Eva, Gist, Alexander, Cooray, Muthutantrige S., Pinto, Joana B. R.

“…The goal of the present study was to investigate the link between elementary school teacher burnout and students' perceptions of teacher social–emotional…”
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Contribution of MASK-air® as a mHealth tool for digitally-enabled person-centred care in rhinitis and asthma by Sousa-Pinto, B, Fonseca, J A, Bousquet, J

“…In chronic diseases, mobile health apps may help to (i) improve clinical management and (ii) provide valuable real-world scientific evidence. In allergic…”
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Development of Ti–Al–V alloys for usage as single-axis knee prostheses: evaluation of mechanical, corrosion, and tribocorrosion behaviors by Pinto, B. O., Torrento, J. E., Grandini, C. R., Galindo, E. L., Pintão, C. A. F., Santos, A. A., Lisboa-Filho, P. N., Pontes, F. M. L., Correa, D. R. N.

“…Single-axis knee prosthesis is an artificial biomechanical device that provides motion to amputees without the need for assistance appliances. Besides it is…”
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Mapping the intestinal alpha-glucogenic enzyme specificities of starch digesting maltase-glucoamylase and sucrase-isomaltase by Jones, Kyra, Sim, Lyann, Mohan, Sankar, Kumarasamy, Jayakanthan, Liu, Hui, Avery, Stephen, Naim, Hassan Y., Quezada-Calvillo, Roberto, Nichols, Buford L., Mario Pinto, B., Rose, David R.

“…Inhibition of intestinal α-glucosidases and pancreatic α-amylases is an approach to controlling blood glucose and serum insulin levels in individuals with Type…”
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Hox transcription factors: an overview of multi-step regulators of gene expression by Carnesecchi, Julie, Pinto, Pedro B, Lohmann, Ingrid

“…Hox transcription factors (TFs) function as key determinants in the specification of cell fates during development. They do so by triggering entire…”
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Predicting mortality in traumatic intracranial hemorrhage by Powers, Andrew Y, Pinto, Mauricio B, Tang, Oliver Y, Chen, Jia-Shu, Doberstein, Cody, Asaad, Wael F

“…Traumatic intracranial hemorrhage (tICH) is a significant source of morbidity and mortality in trauma patients. While prognostic models for tICH outcomes may…”
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Taste cell-expressed α-glucosidase enzymes contribute to gustatory responses to disaccharides by Sukumaran, Sunil K., Yee, Karen K., Iwata, Shusuke, Kotha, Ramana, Quezada-Calvillo, Roberto, Nichols, Buford L., Mohan, Sankar, Pinto, B. Mario, Shigemura, Noriatsu, Ninomiya, Yuzo, Margolskee, Robert F.

“…The primary sweet sensor in mammalian taste cells for sugars and noncaloric sweeteners is the heteromeric combination of type 1 taste receptors 2 and 3…”
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Nutritional strategies to modulate inflammation and oxidative stress pathways via activation of the master antioxidant switch Nrf2 by Cardozo, Ludmila F.M.F., Pedruzzi, Liliana M., Stenvinkel, Peter, Stockler-Pinto, Milena B., Daleprane, Julio B., Leite, Maurilo, Mafra, Denise

“…The nuclear factor E2-related factor 2 (Nrf2) plays an important role in cellular protection against cancer, renal, pulmonary, cardiovascular and…”
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Exploration of the 150 cavity and the role of serendipity in the discovery of inhibitors of influenza virus A neuraminidase by Mohan, Sankar, Pinto, B. Mario

“…Influenza pandemics are an ongoing threat for the human population, as the avian influenza viruses H5N1 and H7N9 continue to circulate in the bird population…”
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