Search Results - "Pinto, Amelia"

SARS-CoV-2 spike protein promotes IL-6 trans-signaling by activation of angiotensin II receptor signaling in epithelial cells by Patra, Tapas, Meyer, Keith, Geerling, Lizzie, Isbell, T Scott, Hoft, Daniel F, Brien, James, Pinto, Amelia K, Ray, Ratna B, Ray, Ranjit

“…Cytokine storm is suggested as one of the major pathological characteristics of SARS-CoV-2 infection, although the mechanism for initiation of a…”
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CD4+T cells mediate protection against Zika associated severe disease in a mouse model of infection by Hassert, Mariah, Wolf, Kyle J, Schwetye, Katherine E, DiPaolo, Richard J, Brien, James D, Pinto, Amelia K

“…Zika virus (ZIKV) has gained worldwide attention since it emerged, and a global effort is underway to understand the correlates of protection and develop…”
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Zika virus pathogenesis in rhesus macaques is unaffected by pre-existing immunity to dengue virus by Pantoja, Petraleigh, Pérez-Guzmán, Erick X., Rodríguez, Idia V., White, Laura J., González, Olga, Serrano, Crisanta, Giavedoni, Luis, Hodara, Vida, Cruz, Lorna, Arana, Teresa, Martínez, Melween I., Hassert, Mariah A., Brien, James D., Pinto, Amelia K., de Silva, Aravinda, Sariol, Carlos A.

“…Zika virus (ZIKV) is a re-emerging virus that has recently spread into dengue virus (DENV) endemic regions and cross-reactive antibodies (Abs) could…”
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Immune response to arbovirus infection in obesity by Hameed, Muddassar, Geerling, Elizabeth, Pinto, Amelia K, Miraj, Iqra, Weger-Lucarelli, James

“…Obesity is a global health problem that affects 650 million people worldwide and leads to diverse changes in host immunity. Individuals with obesity experience…”
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A Dengue Virus Serotype 1 mRNA-LNP Vaccine Elicits Protective Immune Responses by Wollner, Clayton J, Richner, Michelle, Hassert, Mariah A, Pinto, Amelia K, Brien, James D, Richner, Justin M

“…Dengue virus (DENV) is the most common vector-borne viral disease, with nearly 400 million worldwide infections each year concentrated in the tropical and…”
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Function Is More Reliable than Quantity to Follow Up the Humoral Response to the Receptor-Binding Domain of SARS-CoV-2-Spike Protein after Natural Infection or COVID-19 Vaccination by Sariol, Carlos A A, Pantoja, Petraleigh, Serrano-Collazo, Crisanta, Rosa-Arocho, Tiffany, Armina-Rodríguez, Albersy, Cruz, Lorna, Stone, E Taylor Taylor, Arana, Teresa, Climent, Consuelo, Latoni, Gerardo, Atehortua, Dianne, Pabon-Carrero, Christina, Pinto, Amelia K K, Brien, James D D, Espino, Ana M M

“…Both the SARS-CoV-2 pandemic and emergence of variants of concern have highlighted the need for functional antibody assays to monitor the humoral response over…”
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mRNA induced expression of human angiotensin-converting enzyme 2 in mice for the study of the adaptive immune response to severe acute respiratory syndrome coronavirus 2 by Hassert, Mariah, Geerling, Elizabeth, Stone, E Taylor, Steffen, Tara L, Feldman, Madi S, Dickson, Alexandria L, Class, Jacob, Richner, Justin M, Brien, James D, Pinto, Amelia K

“…The novel human coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a pandemic. Critical to the rapid evaluation of vaccines…”
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Metabolic syndrome and aberrant immune responses to viral infection and vaccination: Insights from small animal models by Geerling, Elizabeth, Hameed, Muddassar, Weger-Lucarelli, James, Pinto, Amelia K

“…This review outlines the propensity for metabolic syndrome (MetS) to induce elevated disease severity, higher mortality rates post-infection, and poor…”
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Impact of Obesity on Vaccination to SARS-CoV-2 by Nasr, Michaella-Jana C., Geerling, Elizabeth, Pinto, Amelia K.

“…To combat the immense toll on global public health induced by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), new vaccines were developed. While…”
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Interferon-λ restricts West Nile virus neuroinvasion by tightening the blood-brain barrier by Lazear, Helen M, Daniels, Brian P, Pinto, Amelia K, Huang, Albert C, Vick, Sarah C, Doyle, Sean E, Gale, Jr, Michael, Klein, Robyn S, Diamond, Michael S

“…Although interferon-λ [also known as type III interferon or interleukin-28 (IL-28)/IL-29] restricts infection by several viruses, its inhibitory mechanism has…”
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T Cells in Tick-Borne Flavivirus Encephalitis: A Review of Current Paradigms in Protection and Disease Pathology by Stone, E Taylor, Pinto, Amelia K

“…The family is comprised of a diverse group of arthropod-borne viruses that are the etiological agents of globally relevant diseases in humans. Among these,…”
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Identification of Protective CD8 T Cell Responses in a Mouse Model of Zika Virus Infection by Hassert, Mariah, Harris, Madison G, Brien, James D, Pinto, Amelia K

“…Many flaviviruses including dengue (DENV), and Zika (ZIKV) have attracted significant attention in the past few years. As many flaviviruses are spread by…”
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Metal coordinating inhibitors of Rift Valley fever virus replication by Geerling, Elizabeth, Murphy, Valerie, Mai, Maria C, Stone, E. Taylor, Casals, Andreu Gazquez, Hassert, Mariah, O'Dea, Austin T, Cao, Feng, Donlin, Maureen J, Elagawany, Mohamed, Elgendy, Bahaa, Pardali, Vasiliki, Giannakopoulou, Erofili, Zoidis, Grigoris, Schiavone, Daniel V, Berkowitz, Alex J, Agyemang, Nana B, Murelli, Ryan P, Tavis, John E, Pinto, Amelia K, Brien, James D

“…Rift Valley fever virus (RVFV) is a veterinary and human pathogen and is an agent of bioterrorism concern. Currently, RVFV treatment is limited to supportive…”
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A temporal role of type I interferon signaling in CD8+ T cell maturation during acute West Nile virus infection by Pinto, Amelia K, Daffis, Stephane, Brien, James D, Gainey, Maria D, Yokoyama, Wayne M, Sheehan, Kathleen C F, Murphy, Kenneth M, Schreiber, Robert D, Diamond, Michael S

“…A genetic absence of the common IFN-α/β signaling receptor (IFNAR) in mice is associated with enhanced viral replication and altered adaptive immune responses…”
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Deficient IFN signaling by myeloid cells leads to MAVS-dependent virus-induced sepsis by Pinto, Amelia K, Ramos, Hilario J, Wu, Xiaobo, Aggarwal, Shilpa, Shrestha, Bimmi, Gorman, Matthew, Kim, Kristin Y, Suthar, Mehul S, Atkinson, John P, Gale, Jr, Michael, Diamond, Michael S

“…The type I interferon (IFN) signaling response limits infection of many RNA and DNA viruses. To define key cell types that require type I IFN signaling to…”
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Mouse Models of Heterologous Flavivirus Immunity: A Role for Cross-Reactive T Cells by Hassert, Mariah, Brien, James D, Pinto, Amelia K

“…Most of the world is at risk of being infected with a flavivirus such as dengue virus, West Nile virus, yellow fever virus, Japanese encephalitis virus,…”
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Effective control of early Zika virus replication by Dengue immunity is associated to the length of time between the 2 infections but not mediated by antibodies by Serrano-Collazo, Crisanta, Pérez-Guzmán, Erick X, Pantoja, Petraleigh, Hassert, Mariah A, Rodríguez, Idia V, Giavedoni, Luis, Hodara, Vida, Parodi, Laura, Cruz, Lorna, Arana, Teresa, Martínez, Melween I, White, Laura, Brien, James D, de Silva, Aravinda, Pinto, Amelia K, Sariol, Carlos A

“…Little is known about the contribution of virus-specific and cross-reacting antibodies (Abs) or the cellular immune response generated by a primary dengue…”
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Time elapsed between Zika and dengue virus infections affects antibody and T cell responses by Pérez-Guzmán, Erick X., Pantoja, Petraleigh, Serrano-Collazo, Crisanta, Hassert, Mariah A., Ortiz-Rosa, Alexandra, Rodríguez, Idia V., Giavedoni, Luis, Hodara, Vida, Parodi, Laura, Cruz, Lorna, Arana, Teresa, White, Laura J., Martínez, Melween I., Weiskopf, Daniela, Brien, James D., de Silva, Aravinda, Pinto, Amelia K., Sariol, Carlos A.

“…Zika virus (ZIKV) and dengue virus (DENV) are co-endemic in many parts of the world, but the impact of ZIKV infection on subsequent DENV infection is not well…”
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Prior Heterologous Flavivirus Exposure Results in Reduced Pathogenesis in a Mouse Model of Zika Virus Infection by Hassert, Mariah, Steffen, Tara L, Scroggins, Stephen, Coleman, Abigail K, Shacham, Enbal, Brien, James D, Pinto, Amelia K

“…The 2015/2016 Zika virus epidemic in South and Central America left the scientific community urgently trying to understand the factors that contribute to Zika…”
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CD8+ T Cells Use TRAIL To Restrict West Nile Virus Pathogenesis by Controlling Infection in Neurons by SHRESTHA, Bimmi, PINTO, Amelia K, GREEN, Sharone, BOSCH, Irene, DIAMOND, Michael S

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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