Search Results - "Pinter, MJ"

Crucial Role of Sodium Channel Fast Inactivation in Muscle Fibre Inexcitability in a Rat Model of Critical Illness Myopathy by Rich, Mark M., Pinter, Martin J.

“…Critical illness myopathy is an acquired disorder in which skeletal muscle becomes electrically inexcitable. We previously demonstrated that inactivation of Na…”
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Gap Junctional Coupling and Patterns of Connexin Expression among Neonatal Rat Lumbar Spinal Motor Neurons by Chang, Qiang, Gonzalez, Michael, Pinter, Martin J, Balice-Gordon, Rita J

“…Interneuronal gap junctional coupling is a hallmark of neural development whose functional significance is poorly understood. We have characterized the extent…”
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Sodium channel inactivation in an animal model of acute quadriplegic myopathy by Rich, Mark M., Pinter, Martin J.

“…We previously demonstrated that muscle fibers become unable to fire action potentials in both patients and an animal model of acute quadriplegic myopathy…”
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Central Suppression of Regenerated Proprioceptive Afferents by Haftel, Valerie K, Bichler, Edyta K, Wang, Qing-Bo, Prather, Jonathan F, Pinter, Martin J, Cope, Timothy C

“…Long after a cut peripheral nerve reinnervates muscle and restores force production in adult cats, the muscle does not respond reflexively to stretch…”
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Activity-dependent presynaptic regulation of quantal size at the mammalian neuromuscular junction in vivo by Wang, Xueyong, Li, Yingjie, Engisch, Kathrin L, Nakanishi, Stan T, Dodson, Sara E, Miller, Gary W, Cope, Timothy C, Pinter, Martin J, Rich, Mark M

“…Changes in synaptic activity alter quantal size, but the relative roles of presynaptic and postsynaptic cells in these changes are only beginning to be…”
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Resting potential-dependent regulation of the voltage sensitivity of sodium channel gating in rat skeletal muscle in vivo by Filatov, Gregory N, Pinter, Martin J, Rich, Mark M

“…Normal muscle has a resting potential of -85 mV, but in a number of situations there is depolarization of the resting potential that alters excitability. To…”
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Decreased Synaptic Activity Shifts the Calcium Dependence of Release at the Mammalian Neuromuscular Junction In Vivo by Wang, Xueyong, Engisch, Kathrin L, Li, Yingjie, Pinter, Martin J, Cope, Timothy C, Rich, Mark M

“…We examined the mechanism underlying increased quantal content after block of activity at the mouse neuromuscular junction in vivo. We found that, when quantal…”
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Movement Reduces the Dynamic Response of Muscle Spindle Afferents and Motoneuron Synaptic Potentials in Rat by Haftel, Valerie K, Bichler, Edyta K, Nichols, T. Richard, Pinter, Martin J, Cope, Timothy C

“…1 Department of Physiology, Emory University, Atlanta, Georgia 30322; and 2 Department of Neurobiology, University School of Physical Education, Pozna 60352,…”
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Regulation of Motoneuron Excitability via Motor Endplate Acetylcholine Receptor Activation by Nakanishi, Stan T, Cope, Timothy C, Rich, Mark M, Carrasco, Dario I, Pinter, Martin J

“…Motoneuron populations possess a range of intrinsic excitability that plays an important role in establishing how motor units are recruited. The fact that this…”
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Nerve Injury Induces Gap Junctional Coupling among Axotomized Adult Motor Neurons by Chang, Qiang, Pereda, Alberto, Pinter, Martin J, Balice-Gordon, Rita J

“…Neonatal spinal motor neurons are electrically and dye-coupled by gap junctions, but coupling is transient and disappears rapidly after birth. Here we report…”
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Loss of electrical excitability in an animal model of acute quadriplegic myopathy by Rich, M M, Pinter, M J, Kraner, S D, Barchi, R L

“…In rats treated with high-dose corticosteroids, skeletal muscle that is denervated in vivo (steroid-denervated [S-D]) develops electrical inexcitability…”
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Reduced Neuromuscular Quantal Content With Normal Synaptic Release Time Course and Depression in Canine Motor Neuron Disease by Rich, Mark M, Wang, Xueyong, Cope, Timothy C, Pinter, Martin J

“…  1 Department of Physiology and   2 Department of Neurology, Emory University School of Medicine, Atlanta, Georgia 30322 Rich, Mark M., Xueyong Wang, Timothy…”
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Time courses of calcium and calcium-bound buffers following calcium influx in a model cell by Nowycky, M.C., Pinter, M.J.

“…Fixed and diffusible calcium (Ca) buffers shape the spatial and temporal distribution of free Ca following Ca entry through voltage-gated ion channels. This…”
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Activity-Driven Synaptic and Axonal Degeneration in Canine Motor Neuron Disease by Carrasco, Dario I, Rich, Mark M, Wang, Qingbo, Cope, Timothy C, Pinter, Martin J

“…1 Departments of Physiology and 2 Neurology, Emory University School of Medicine, Atlanta, Georgia 30322 Submitted 17 February 2004; accepted in final form 15…”
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Reduced Endplate Currents Underlie Motor Unit Dysfunction in Canine Motor Neuron Disease by Rich, Mark M, Waldeck, Robert. F, Cork, Linda C, Balice-Gordon, Rita J, Fyffe, Robert E. W, Wang, Xueyong, Cope, Timothy C, Pinter, Martin J

“…  1 Department of Physiology and   2 Department of Neurology, Emory University School of Medicine, Atlanta, Georgia 30322;   3 Department of Neurobiology and…”
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Functional motor unit failure precedes neuromuscular degeneration in canine motor neuron disease by Balice-Gordon, Rita J., Smith, Daniel B. J., Goldman, Joshua, Cork, Linda C., Shirley, Anne, Cope, Timothy C., Pinter, Martin J.

“…Hereditary canine spinal muscular atrophy (HCSMA) features rapidly progressive muscle weakness that affects muscles in an apparent proximal‐to‐distal gradient…”
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Homologous transplantation of prepubertal testes in the dog by Pullium, J K, Lin, P H, Pinter, M J

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Regenerated dorsal root fibers form functional synapses in embryonic spinal cord transplants by Itoh, Y, Waldeck, R F, Tessler, A, Pinter, M J

“…1. The aim of the present study was to determine whether synapses formed by dorsal root afferents that regenerate into intraspinal transplants of fetal spinal…”
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Adult spinal motoneurons remain viable despite prolonged absence of functional synaptic contact with muscle by Vanden Noven, S, Wallace, N, Muccio, D, Turtz, A, Pinter, M J

“…Several rat medial gastrocnemius (MG) motor axons were allowed to regenerate into normally innervated muscle. Under these conditions, synapse formation is…”
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Motor unit behavior in canine motor neuron disease by Pinter, MJ, Waldeck, RF, Wallace, N, Cork, LC

“…Hereditary canine spinal muscular atrophy (HCSMA) is an autosomally dominant disease of motor neurons that shares many pathological features with human motor…”
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