Search Results - "Pinna, G A"

Synthesis of biologically active bridged diazabicycloheptanes by Murineddu, G, Asproni, B, Pinna, G, Curzu, M M, Dore, A, Pau, A, Deligia, F, Pinna, G A

“…The chemistry underlying how diazabicycloheptanes are assembled is described, subdivided according to chemical structure of two types, the 3,6…”
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An overview on different classes of viral entry and respiratory syncitial virus (RSV) fusion inhibitors by Murineddu, G, Murruzzu, C, Pinna, G A

“…The therapeutic approach to AIDS is based on the combination of different drugs in the highly active antiretroviral therapy (HAART) regimen. These drugs have a…”
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The novel cannabinoid antagonist SM-11 reduces hedonic aspect of food intake through a dopamine-dependent mechanism by Fois, G.R., Fattore, L., Murineddu, G., Salis, A., Pintore, G., Asproni, B., Pinna, G.A., Diana, M.

“…[Display omitted] Cannabinoids, endogenous and exogenously administered, are known to positively regulate food intake and energy balance. Since CB1 receptor…”
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Synthesis and aldose reductase inhibitory activities of novel thienocinnolinone derivatives by Pau, A, Asproni, B, Boatto, G, Grella, G.E, De Caprariis, P, Costantino, L, Pinna, G.A

“…A novel series of tetrahydrothieno[2,3- h]cinnolinone derivatives were synthesized and evaluated in vitro for their ability to inhibit aldose reductase (ALR2),…”
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Synthesis and cytotoxicity of substituted 2-benzylnaphth[2,3- d]imidazoles by Grella, G.E, Cabras, M.C, Murineddu, G, Pau, A, Pinna, G.A

“…Designed as a new series of so called “bivalent ligand” containing the proposed 2-benzylnaphthimidazole-type structure, a number of 2-benzylnaphth[2,3-…”
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Synthesis and Anti-HIV-1 Activity of New Delavirdine Analogues Carrying Arylpyrrole Moieties by PINNA, Gérard Aimè, LORIGA, Giovanni, MURINEDDU, Gabriele, GRELLA, Giuseppe, MURA, Massimo, VARGIU, Laura, MURGIONI, Chiara, COLLA, Paolo LA

“…In our search for novel anti-human immunodeficiency virus (HIV)-1 agents, 14 delavirdine analogues were synthesized and evaluated as potential anti-HIV-1…”
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Adventitious buds on roots of Siphanthera arenaria (DC.) Cogn. (Melastomataceae), an annual plant from the cerrado biome by Menezes-e-Vasconcelos, K., Melo-de-Pinna, G. F. A.

“…Plants from Brazilian tropical grasslands of the cerrado biome (also referred to as the Cerrado region) are characterized by the possessing of belowground…”
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Synthesis, Molecular Modeling, and Opioid Receptor Affinity of 9,10-Diazatricyclo[4.2.1.12,5]decanes and 2,7-Diazatricyclo[4.4.0.03,8]decanes Structurally Related to 3,8-Diazabicyclo[3.2.1]octanes by Vianello, Paola, Albinati, Alberto, Pinna, Gerardo A, Lavecchia, Antonio, Marinelli, Luciana, Borea, Pier Andrea, Gessi, Stefania, Fadda, Paola, Tronci, Silvia, Cignarella, Giorgio

“…Various lines of evidence, including molecular modeling studies, imply that the endoethylenic bridge of 3,8-diazabicyclo[3.2.1]octanes (DBO, 1) plays an…”
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Synthesis and cytotoxicity evaluation of thiophene analogues of 1-methyl-2,3-bis(hydroxymethyl)benzo[ g]indole bis[ N-(2-propyl)carbamate] by Pirisi, M.A, Murineddu, G, Mussinu, J.M, Pinna, G.A

“…The cytotoxicity of the bis[ N-(2-propyl)carbamates] 2 and 3 which are linked to thieno[ i, j- g]indole scaffolds through methylene bridges were studied as…”
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Tricyclic Pyrazoles. 3. Synthesis, Biological Evaluation, and Molecular Modeling of Analogues of the Cannabinoid Antagonist 8-Chloro-1-(2‘,4‘-dichlorophenyl)-N-piperidin-1-yl-1,4,5,6- tetrahydrobenzo[6,7]cyclohepta[1,2-c]pyrazole-3-carboxamide by Murineddu, Gabriele, Ruiu, Stefania, Loriga, Giovanni, Manca, Ilaria, Lazzari, Paolo, Reali, Roberta, Pani, Luca, Toma, Lucio, Pinna, Gérard A

“…A series of analogues of 8-chloro-1-(2‘,4‘-dichlorophenyl)-N-piperidin-1-yl-1,4,5,6-tetrahydrobenzo[6,7]cyclohepta[1,2-c]pyrazole-3-carboxamide 4a (NESS 0327)…”
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Synthesis and μ-opioid receptor affinity of a new series of nitro substituted 3,8-diazabicyclo[3.2.1]octane derivatives by Barlocco, D., Cignarella, G., Vianello, P., Villa, S., Pinna, G.A., Fadda, P., Fratta, W.

“…A new series of analogues (1c–j; 2c–i) of the previously reported analgesic 3,8-diazabicyclo[3.2.l]octanes (1a,b; 2a,b) was synthesized and tested for their…”
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Benzocondensed derivatives as rigid analogues of the μ-opioid agonist 3(8)-cinnamyl-8(3)-propionyl-3,8-diazabicyclo[3.2.1]octanes: synthesis, modeling, and affinity by Cignarella, G, Barlocco, D, Vianello, P, Villa, S, Pinna, G.A, Fadda, P, Fratta, W, Toma, L, Gessi, S

“…A new series of rigid analogues ( 1a–g, 2a–g) of the previously reported analgesic 3-cinnamyl-8-propionyl-3,8-diazabicyclo[3.2.1]octane ( I) and its reverted…”
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Synthesis and pharmacological evaluation of 4a-methyl-4,4a,5,6-tetrahydrothieno[2,3-h]cinnolin-3(2H)-ones by Pinna, G A, Salis, E, Berta, D, Gavini, E, D'Amico, M

“…A number of 4a-methyl-4,4a,5,6-tetrahydrothieno[2,3-h]cinnolin-3(2H)-one s (3-5) have been synthesized and tested for their pharmacological profile. These were…”
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Morphology and anatomy of a leaf mine in Vismia guianensis (Aubl.) Choisy (Clusiaceae) in a fragment of Brazilian Atlantic forest by Almeida-Cortez, J S, Melo-de-Pinna, G F A

“…Mines or hyponomes are channels caused by larva miners consuming internal plant tissues. These miners live on the leaf and feed from these tissues. Leaf mines…”
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Synthesis, modelling, and μ-opioid receptor affinity of N-3(9)-arylpropenyl- N-9(3)-propionyl-3,9-diazabicyclo[3.3.1]nonanes by Pinna, G.A, Murineddu, G, Curzu, M.M, Villa, S, Vianello, P, Borea, P.A, Gessi, S, Toma, L, Colombo, D, Cignarella, G

“…A series of N-3-arylpropenyl- N-9-propionyl-3,9-diazabicyclo[3.3.1]nonanes ( 1a–g) and of reverted N-3-propionyl- N-9-arylpropenyl isomers ( 2a–g), as…”
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Synthesis and pharmacological evaluation of 4,4a,5,6-tetrahydro-7,8-disubstituted-benzo[h]cinnolin-3(2H)-ones by Pinna, G A, Loriga, M, Curzu, M M, D'Amico, M

“…7,8-disubstituted-4,4a,5,6-tetrahydrobenzo[h]cinnolin-3(2H)-ones 2-4 have been synthesized and tested in comparison with the 8-acetylamino-4,4a,5,…”
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Pyridazine N-oxides. II. Synthesis and in vitro antimicrobial evaluation of 3-chloro-4-carbamoyl-5-aryl-6-methyl-pyridazine N-oxides by Gavini, E, Juliano, C, Mulè, A, Pirisino, G, Pinna, G A

“…As a part of a research project on antimicrobial agents, various novel carbamoyl derivatives of pyridazine-N-oxides 7a-j were prepared in moderate to good…”
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Synthesis and pharmacological evaluation of 5,6-dihydrobenzo[f] cinnolin-2(3H)ones analogues of antihypertensive and antiaggregating benzo[h]cinnolinones by Pinna, G A, Curzu, M M, Fraghì, P, Gavini, E, D'Amico, M

“…Two new dihydrobenzo[f]cinnolin-2(3H)ones (4a,b) have been synthesized and tested for their hypotensive, antihypertensive and antiaggregating activities in…”
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Morphology and anatomy of leaf mine in Richterago riparia Roque (Asteraceae) in the campos rupestres of Serra do Cipó, Brazil by Melo De Pinna, G F A, Kraus, J E, de Menezes, N L

“…The leaf mine in Richterago riparia is caused by a lepidopteran larva (lepidopteronome). The leaves of R. riparia show campdodrome venation; the epidermis is…”
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Synthesis of 1-methyl-2,3-dimethyl-N(isopropyl)carbamates-4,5-dihydro-7-R'- 8-R-1H-benzo[g]indoles and evaluation of in vitro anticancer activity by Pinna, G A, Pirisi, M A, Paglietti, G

“…The synthesis of 7-mono or 7,8-disubstituted 4,5-dihydro-1-methyl-1H- benzo[g]indoles bearing a methyl-N-isopropylcarbamate group in position 2 or 2,3 of the…”
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