Search Results - "Pinho, E V"
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1
Diels-Alder Cycloaddition Reactions in Sustainable Media
Published in Molecules (Basel, Switzerland) (15-02-2022)“…Diels-Alder cycloaddition reaction is one of the most powerful strategies for the construction of six-membered carbocyclic and heterocyclic systems, in most…”
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2
Isolation and Identification of Cytotoxic Compounds Present in Biomaterial Life
Published in Materials (24-01-2022)“…Direct pulp capping consists of a procedure in which a material is directly placed over the exposed pulp to maintain dental vitality. Although still widely…”
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3
Novel fluorinated ring-fused chlorins as promising PDT agents against melanoma and esophagus cancer
Published in RSC medicinal chemistry (28-04-2021)“…Investigation of novel 4,5,6,7-tetrahydropyrazolo[1,5- a ]pyridine-fused chlorins, derived from 5,10,15,20-tetrakis(pentafluorophenyl)porphyrin, as PDT agents…”
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4
Cholesteryl Hemiazelate Present in Cardiovascular Disease Patients Causes Lysosome Dysfunction in Murine Fibroblasts
Published in Cells (Basel, Switzerland) (01-12-2023)“…There is growing evidence supporting the role of fibroblasts in all stages of atherosclerosis, from the initial phase to fibrous cap and plaque formation. In…”
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5
Aziridines in Formal [3+2] Cycloadditions: Synthesis of Five-Membered Heterocycles
Published in European journal of organic chemistry (01-11-2012)“…Chemistry based on ring opening of aziridines has been widely studied in organic synthesis. However, it has mainly been centered on ring opening by…”
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6
High Instantaneous Inhibitory Potential of Bictegravir and the New Spiro-β-Lactam BSS-730A for HIV-2 Isolates from RAL-Naïve and RAL-Failing Patients
Published in International journal of molecular sciences (18-11-2022)“…Integrase inhibitors (INIs) are an important class of drugs for treating HIV-2 infection, given the limited number of drugs active against this virus. While…”
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7
Verification and characterization of chromosome duplication in haploid maize
Published in Genetics and molecular research (26-06-2015)“…Doubled haploid technology has been used by various private companies. However, information regarding chromosome duplication methodologies, particularly those…”
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3-(1,2,3-Triazol-4-yl)-β-Carbolines and 3-(1 H -Tetrazol-5-yl)-β-Carbolines: Synthesis and Evaluation as Anticancer Agents
Published in Pharmaceuticals (Basel, Switzerland) (03-12-2022)“…Herein, the synthesis and anticancer activity evaluation of a series of novel β-carbolines is reported. The reactivity of nitrosoalkenes towards indole was…”
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9
Synthesis of novel chiral spiro-β-lactams from nitrile oxides and 6-()-(benzoylmethylene)penicillanate: batch, microwave-induced and continuous flow methodologies
Published in RSC advances (27-10-2022)“…The first examples of the diastereoselective 1,3-dipolar cycloaddition reaction of nitrile oxides and 6-alkylidene penicillanates leading to chiral…”
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10
Selective Synthesis of 3‑(1H‑Tetrazol-5-yl)-indoles from 2H‑Azirines and Arynes
Published in ACS omega (24-06-2024)“…A new selective synthetic approach to indole derivatives bearing a tetrazole moiety has been developed. Arynes, generated in situ from o-(trimethylsilyl)aryl…”
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11
Flow Chemistry: Towards A More Sustainable Heterocyclic Synthesis
Published in European journal of organic chemistry (24-11-2019)“…Flow Chemistry is a revolutionary field in Organic Chemistry. By changing the conventional methods and apparatus applied in the chemical synthesis, flow…”
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12
Reactivity of ethyl nitrosoacrylate toward pyrrole, indole and pyrrolo[3,2-c]carbazole: an experimental and theoretical study
Published in Frontiers in chemistry (08-08-2023)“…Nitrosoalkenes react with 8-methyl-1,6-dihydropyrrolo[3,2- c ]carbazole to give both 2- and 3-alkylated products via hetero-Diels-Alder reaction followed by…”
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13
Unveiling a family of spiro-β-lactams with anti-HIV and antiplasmodial activity via phosphine-catalyzed [3+2] annulation of 6-alkylidene-penicillanates and allenoates
Published in Frontiers in chemistry (07-10-2022)“…The molecular architecture of spirocyclic compounds has been widely explored within the medicinal chemistry field to obtain new compounds with singular…”
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14
Applications of Photodynamic Therapy in Endometrial Diseases
Published in Bioengineering (Basel) (23-05-2022)“…Photodynamic therapy (PDT) is a medical procedure useful for several benign conditions (such as wound healing and infections) and cancer. PDT is minimally…”
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15
Synthesis of New 2-Halo-2-(1H-tetrazol-5-yl)-2H-azirines via a Non-Classical Wittig Reaction
Published in Molecules (Basel, Switzerland) (12-12-2015)“…The synthesis and reactivity of tetrazol-5-yl-phosphorus ylides towards N-halosuccinimide/TMSN₃ reagent systems was explored, opening the way to new…”
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16
Immobilized Catalysts for Hydroformylation Reactions: A Versatile Tool for Aldehyde Synthesis
Published in European journal of organic chemistry (01-11-2012)“…Olefin hydroformylation is a widely used process, both on large scales and in fine chemistry, with catalyst reuse still being one of the main objectives. In…”
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17
The Pyrolysis of Isoxazole Revisited: A New Primary Product and the Pivotal Role of the Vinylnitrene. A Low-Temperature Matrix Isolation and Computational Study
Published in Journal of the American Chemical Society (23-11-2011)“…This paper describes the pyrolysis of parent isoxazole and of its 5-methyl and 3,5-dimethyl derivatives by the high-pressure pulsed pyrolysis method, where…”
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18
A Review on (Hydro)Porphyrin-Loaded Polymer Micelles: Interesting and Valuable Platforms for Enhanced Cancer Nanotheranostics
Published in Pharmaceutics (15-02-2019)“…Porphyrins are known therapeutic agents for photodynamic therapy of cancer and also imaging agents for NIR fluorescence imaging, MRI, or PET. A combination of…”
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19
Genes related to high temperature tolerance during maize seed germination
Published in Genetics and molecular research (22-12-2015)“…The identification of genes related to heat tolerance is fundamental for the development of high-quality seeds that are tolerant to heat stress condition. The…”
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20
Relationship among physiological quality, heterosis, and amylase gene expression in maize seeds
Published in Genetics and molecular research (31-07-2015)“…In this study, we analyzed heterosis, amylase enzyme gene expression, and the physiological quality of maize seeds with different genotypes and sizes, which…”
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