Search Results - "Pinho, Cristiane Figueiredo"
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Regulatory and junctional proteins of the blood-testis barrier in human Sertoli cells are modified by monobutyl phthalate (MBP) and bisphenol A (BPA) exposure
Published in Toxicology in vitro (01-08-2016)“…The blood-testis barrier (BTB) is responsible for providing a protected environment and coordinating the spermatogenesis. Endocrine disruptors (EDs) might lead…”
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Panax ginseng methabolit (GIM-1) prevents oxidative stress and apoptosis in human Sertoli cells exposed to Monobutyl-phthalate (MBP)
Published in Reproductive toxicology (Elmsford, N.Y.) (01-06-2019)“…•MBP increases apoptosis in HSec Sertoli cells.•MBP induces oxidative stress by suppressing antioxidant enzymes.•GIM-1 improves antioxidant mechanisms in HSec…”
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Raloxifene decreases cell viability and migratory potential in prostate cancer cells (LNCaP) with GPR30/GPER1 involvement
Published in Journal of pharmacy and pharmacology (01-07-2019)“…Objectives This study evaluated raloxifene (ral) effects on LNCaP prostate tumour cells modulating the activity of GPER1/GPR30 receptors. Methods LNCaP cells…”
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Exposure to Dichlorvos pesticide alters the morphology of and lipid metabolism in the ventral prostate of rats
Published in Frontiers in toxicology (04-07-2023)“…Organophosphate pesticides are widely used in agriculture, leading to soil, water, and food contamination. Among these compounds is Dichlorvos [O,O-dimethyl…”
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Panax ginseng metabolite (GIM-1) modulates the effects of monobutyl phthalate (MBP) on the GPR30/GPER1 canonical pathway in human Sertoli cells
Published in Reproductive toxicology (Elmsford, N.Y.) (01-09-2020)“…•MBP modulates the GPR30/GPER1 canonical pathway in human Sertoli cells (HSeC).•MBP enhances cofilin expression and affects F-actin stability in HSeC.•GIM-1…”
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Protective effect of resveratrol on urogenital sinus and prostate development in rats exposed in utero to TCDD (2,3,7,8-tetrachlorodibenzo-p-dioxin)
Published in Reproductive toxicology (Elmsford, N.Y.) (01-01-2019)“…•Gestational TCDD exposure altered prostate development in male rats.•Maternal resveratrol intake reduced disorders induced by TCDD on both early and late…”
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Combinatorial Effect of Abiraterone Acetate and NVP-BEZ235 on Prostate Tumor Progression in Rats
Published in Hormones & cancer (01-06-2018)“…Use of drug combinations that target different pathways involved in the development and progression of prostate cancer (PCa) has emerged as an alternative to…”
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