Search Results - "Pinheiro, Sérgio V. B."
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A long-lasting oral preformulation of the angiotensin II AT1 receptor antagonist losartan
Published in Drug development and industrial pharmacy (02-09-2018)“…Losartan (Los), a non-peptidic orally active agent, reduces arterial pressure through specific and selective blockade of angiotensin II receptor AT1. However,…”
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2
Risk of hypertension in primary vesicoureteral reflux
Published in Pediatric nephrology (Berlin, West) (01-03-2007)“…The aim of this report was to estimate the risk of hypertension in children with primary vesicoureteral reflux (VUR). Between 1970 and 2004, 735 patients were…”
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3
The role of angiotensin‐(1–7) receptor Mas in spermatogenesis in mice and rats
Published in Journal of anatomy (01-05-2009)“…Evidence regarding the components of the renin–angiotensin (Ang) system suggests that this system plays an important role in male reproduction. However, there…”
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4
Impairment of In Vitro and In Vivo Heart Function in Angiotensin-(1-7) Receptor Mas Knockout Mice
Published in Hypertension (Dallas, Tex. 1979) (01-05-2006)“…In this study we investigated the effects of the genetic deletion of the angiotensin (Ang)-(1-7) receptor Mas on heart function. Localization of Mas in the…”
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5
Genetic deletion of the angiotensin-(1–7) receptor Mas leads to glomerular hyperfiltration and microalbuminuria
Published in Kidney international (01-06-2009)“…Angiotensin-(1–7), an active fragment of both angiotensins I and II, generally opposes the vascular and proliferative actions of angiotensin II. Here we…”
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6
The Oxford Classification predictors of chronic kidney disease in pediatric patients with IgA nephropathy
Published in Jornal de pediatria (01-07-2017)“…The Oxford Classification for Immunoglobulin A nephropathy (IgAN) identifies pathological variables that may predict the decline of renal function. This study…”
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Angiotensin-(1-7) and its receptor as a potential targets for new cardiovascular drugs
Published in Expert opinion on investigational drugs (01-08-2005)“…The identification of novel biochemical components of the renin-angiotensin system (RAS) has added a further layer of complexity to the classical concept of…”
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8
Renal function in transgenic rats expressing an angiotensin-(1–7)-producing fusion protein
Published in Regulatory peptides (10-12-2006)“…Transgenic rats [TGR(A1–7)3292] present a chronic 2.5-fold increase in plasma Angiotensin-(1–7) [Ang-(1–7)] concentration. In the present study, we…”
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9
Angiotensin-converting enzyme inhibition increases glucose-induced insulin secretion in response to acute restraint
Published in Clinical and experimental pharmacology & physiology (01-12-2012)“…Summary There is increasing evidence suggesting involvement of the renin–angiotensin system (RAS) in carbohydrate metabolism and its response to stress. Thus,…”
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10
Selective increase of angiotensin(1-7) and its receptor in hearts of spontaneously hypertensive rats subjected to physical training
Published in Experimental physiology (01-05-2008)“…In the present study we investigated the effects of physical training on plasma and cardiac angiotensin(1-7) [Ang(1-7)] levels. In addition, possible changes…”
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Characterization of a New Selective Antagonist for Angiotensin-(1–7), d-Pro7-Angiotensin-(1–7)
Published in Hypertension (Dallas, Tex. 1979) (01-03-2003)“…ABSTRACT—Angiotensin-(1–7) [Ang-(1–7)] has biological actions that can often be distinguished from those of angiotensin II (Ang II). Recent studies indicate…”
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Chronic infusion of angiotensin-(1–7) reduces heart angiotensin II levels in rats
Published in Regulatory peptides (15-02-2005)“…We tested the hypothesis that the actions of Angiotensin (Ang)-(1–7) in the heart could involve changes in tissue levels of Ang II. This possibility was…”
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13
Selective increase of angiotensin(1â7) and its receptor in hearts of spontaneously hypertensive rats subjected to physical training
Published in Experimental physiology (01-05-2008)“…In the present study we investigated the effects of physical training on plasma and cardiac angiotensin(1â7) [Ang(1â7)] levels. In addition, possible…”
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14
The therapeutic potential of Angiotensin-(1-7) as a novel Renin-Angiotensin System mediator
Published in Mini reviews in medicinal chemistry (01-05-2006)“…In this review, we show Angiotensin-(1-7) as a novel Renin Angiotensin System mediator that antagonizes cardiovascular and proliferative effects of Angiotensin…”
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