Search Results - "Pinheiro, Daphne"
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Mechanisms Underlying Cell Therapy in Liver Fibrosis: An Overview
Published in Cells (Basel, Switzerland) (29-10-2019)“…Fibrosis is a common feature in most pathogenetic processes in the liver, and usually results from a chronic insult that depletes the regenerative capacity of…”
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Cytokines, hepatic cell profiling and cell interactions during bone marrow cell therapy for liver fibrosis in cholestatic mice
Published in PloS one (27-11-2017)“…Bone marrow cells (BMC) migrate to the injured liver after transplantation, contributing to regeneration through multiple pathways, but mechanisms involved are…”
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Secretome effect of adipose tissue-derived stem cells cultured two-dimensionally and three-dimensionally in mice with streptozocin induced type 1 diabetes
Published in Current research in pharmacology and drug discovery (01-01-2021)“…To analyze therapeutic potential of the conditioned medium from adipose tissue-derived stem cells (ASC) cultivated in 2D (CM-2D) and 3D (CM-3D) models, in mice…”
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Effects of mesenchymal stem cells conditioned medium treatment in mice with cholestatic liver fibrosis
Published in Life sciences (1973) (15-09-2021)“…The purpose of this work was to study the effects of mesenchymal stem cells conditioned medium (MSC CM) treatment in animals with cholestatic liver fibrosis…”
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APX2009 sensitizes hypoxic breast cancer cells to doxorubicin by increasing its accumulation and caspase-3/7-mediated apoptosis
Published in Breast cancer research and treatment (13-10-2024)“…The association of targeted therapy with chemotherapy is encouraged to increase the treatment efficiency, especially in hypoxic triple-negative breast cancer…”
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Profiles of Expression of SAV1 in Normoxia or Hypoxia Microenviroment are Associated with Breast Cancer Prognosis
Published in Archives of medical research (01-02-2023)“…In breast cancer (BC), hypoxia is associated with poor prognosis. Protein Salvador homolog 1 (SAV1) acts as a tumor suppressor and is downregulated in the…”
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Bone marrow mononuclear cell transplantation improves mitochondrial bioenergetics in the liver of cholestatic rats
Published in Experimental cell research (01-08-2015)“…Mitochondrial dysfunction has been associated with liver cholestatis. Toxic bile salt accumulation leads to chronic injury with mitochondrial damage, ROS…”
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Hematopoietic changes in the offspring induced by maternal overweight: Effect on placenta and fetal liver populations
Published in Placenta (Eastbourne) (01-04-2018)“…Bone marrow cells (BMC) from obese adult mice display an increased apoptosis rate over proliferation. Hematopoietic stem cells (HSC) form all blood cells and…”
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