Search Results - "Pinheiro, Carina Silva"
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Recombinant T‐cell epitope conjugation: A new approach for Dermatophagoides hypoallergen design
Published in Clinical and experimental allergy (01-02-2023)“…Background Allergen‐specific immunotherapy (AIT) is the only clinical approach that can potentially cure some allergic diseases by inducing immunological…”
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Purification and characterisation of the dimeric group 12 allergen from Blomia tropicalis heterologously expressed by Escherichia coli Top10F
Published in Molecular biology reports (01-04-2021)“…Successful research in the wide-ranging field of allergy is usually achieved by definition not only of physicochemical and immunological properties of natural,…”
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DNA Vaccine Encoding the Chimeric Form of Schistosoma mansoni Sm-TSP2 and Sm29 Confers Partial Protection against Challenge Infection
Published in PloS one (05-05-2015)“…Schistosomiasis is an important parasitic disease worldwide that affects more than 207 million people in 76 countries and causes approximately 250,000 deaths…”
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Protective response mediated by immunization with recombinant proteins in a murine model of toxocariasis and canine infection by Toxocara canis
Published in Vaccine (07-02-2022)“…•Recombinant proteins obtained by vaccinology reverse protected mice against T. canis.•First recombinant protein vaccine to be clinically tested in canines…”
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Recombinant proteins of helminths with immunoregulatory properties and their possible therapeutic use
Published in Acta tropica (01-02-2017)“…[Display omitted] •The current approaches for identification of helminth proteins with potential immunoregulatory properties.•Methodological approaches and…”
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Allergens of Blomia tropicalis: An Overview of Recombinant Molecules
Published in International archives of allergy and immunology (01-05-2017)“…Allergic diseases are considered a major problem for healthcare systems in both developed and developing countries. House dust mites are well-known triggers of…”
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Proteomic Analysis Reveals Allergen Variability among Breeds of the Dust Mite Blomia tropicalis
Published in International archives of allergy and immunology (01-10-2019)“…The dawn of the "omics" technologies has changed allergy research, increasing the knowledge and identification of new allergens. However, these studies have…”
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A hybrid of two major Blomia tropicalis allergens as an allergy vaccine candidate
Published in Clinical and experimental allergy (01-07-2020)“…Introduction Allergen‐specific immunotherapy (AIT) represents a curative approach for treating allergies. In the tropical and subtropical regions of the world,…”
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N‐terminal peptide deletion influences immunological and structural features of Blo t 5
Published in Allergy (Copenhagen) (01-06-2020)Get full text
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Corrigendum to “Advances in Immunology of Neglected Tropical Diseases: New Control Tools and Prospects for Disease Elimination”
Published in Journal of immunology research (24-10-2020)“…In the article titled “Advances in Immunology of Neglected Tropical Diseases: New Control Tools and Prospects for Disease Elimination” [1], author Nestor…”
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Advances in Immunology of Neglected Tropical Diseases: New Control Tools and Prospects for Disease Elimination
Published in Journal of immunology research (2020)“…Neglected tropical diseases (NTD) comprise a group of infectious viral, bacterial, and parasitic diseases with high endemicity in tropical and subtropical…”
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Proteomics and immunoblotting analyses reveal antigens that optimize the immunodiagnosis of the infection by Toxocara spp
Published in Transboundary and emerging diseases (01-09-2022)“…Toxocariasis is an infection caused by the round worms Toxocara canis and Toxocara cati. It occurs worldwide though it is more prevalent in developing…”
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The hybrid protein BTH2 suppresses allergic airway inflammation in a murine model of HDM‐specific immunotherapy
Published in Clinical and experimental allergy (01-08-2023)“…Background Allergen‐specific immunotherapy (AIT) is the only disease‐modifying treatment approach to change disease‐causing allergens. Hypoallergenic…”
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Systematic review and meta-analysis of the association of infection with Toxocara canis with atopy and asthma
Published in Revista de investigaciones veterinarias del Perú (01-03-2024)“…ABSTRACT The human toxocariasis is the most important cosmopolite helminth infection in the world. The infection can modulate the immune response of the…”
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PCR-RFLP screening of polymorphisms associated with benzimidazole resistance in Necator americanus and Ascaris lumbricoides from different geographical regions in Brazil
Published in PLoS neglected tropical diseases (01-09-2018)“…Ascaris lumbricoides and Necator americanus are soil-transmitted parasites with global geographic distribution, and they represent some of the most common and…”
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Immunogenicity and protection induced by recombinant Toxocara canis proteins in a murine model of toxocariasis
Published in Vaccine (19-06-2020)“…•In Silico data were used for the selection of T. canis antigens as vaccine candidate.•T. canis recombinant antigens were used effectively for the control of…”
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Therapeutic potential of a novel hybrid protein: Mitigating allergy and airway remodeling in chronic asthma models induced by Dermatophagoides pteronyssinus
Published in Molecular immunology (01-11-2024)“…The house-dust mite Dermatophagoides pteronyssinus is a key trigger of allergic asthma. Therefore, it is essential to develop new vaccines that can alter…”
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Dermatophagoides spp. hypoallergens design: what has been achieved so far?
Published in Expert opinion on therapeutic patents (03-03-2020)“…: Allergic illnesses are one of the most prevalent immunological disorders worldwide and house dust mites are important triggers of these diseases…”
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Advances in patent applications related to allergen immunotherapy
Published in Expert opinion on therapeutic patents (02-06-2016)“…Allergies are among the most prevalent chronic diseases worldwide. Allergen-specific immunotherapy is used as an alternative treatment to pharmacotherapy…”
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Blomia tropicalis Blo t 5 and Blo t 21 recombinant allergens might confer higher specificity to serodiagnostic assays than whole mite extract
Published in BMC immunology (27-02-2013)“…Blomia tropicalis is a dust mite and an important source of allergens in tropical regions. Up to now, the assays to diagnose atopy to this mite use whole body…”
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