Search Results - "Pinheiro, Antônio Mateus"
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Hippocampal cytogenesis abrogation impairs inter-regional communication between the hippocampus and prefrontal cortex and promotes the time-dependent manifestation of emotional and cognitive deficits
Published in Molecular psychiatry (01-12-2021)“…Impaired ability to generate new cells in the adult brain has been linked to deficits in multiple emotional and cognitive behavioral domains. However, the…”
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Differential and converging molecular mechanisms of antidepressants' action in the hippocampal dentate gyrus
Published in Neuropsychopharmacology (New York, N.Y.) (01-01-2015)“…Major depression is a highly prevalent, multidimensional disorder. Although several classes of antidepressants (ADs) are currently available, treatment…”
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Valuing Mundane Manifestations of Rare, but Underdiagnosed, Diseases in Portugal: The Example of McArdle Disease
Published in Acta medica portuguesa (01-03-2023)Get full text
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The effects of chronic stress on hippocampal adult neurogenesis and dendritic plasticity are reversed by selective MAO-A inhibition
Published in Journal of psychopharmacology (Oxford) (01-12-2014)“…There is accumulating evidence that adult neurogenesis and dendritic plasticity in the hippocampus are neuroplastic phenomena, highly sensitive to the effects…”
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Suppression of adult cytogenesis in the rat brain leads to sex‐differentiated disruption of the HPA axis activity
Published in Cell proliferation (01-02-2022)“…Objectives The action of stress hormones, mainly glucocorticoids, starts and coordinates the systemic response to stressful events. The HPA axis activity is…”
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Cell cycle regulation of hippocampal progenitor cells in experimental models of depression and after treatment with fluoxetine
Published in International journal of molecular sciences (30-10-2021)“…Changes in adult hippocampal cell proliferation and genesis have been largely implicated in depression and antidepressant action, though surprisingly, the…”
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Re-cycling Paradigms: Cell Cycle Regulation in Adult Hippocampal Neurogenesis and Implications for Depression
Published in Molecular neurobiology (01-08-2013)“…Since adult neurogenesis became a widely accepted phenomenon, much effort has been put in trying to understand the mechanisms involved in its regulation. In…”
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Nutrient and Heavy Metals Release from Mixtures of Organic Residues and Food Wastes in Composting
Published in Water, air, and soil pollution (01-06-2020)“…Composting has various benefits to achieve sustainability, such as substituting the use of fertilizers and preventing organic residues from being dumped in…”
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miR-409 and miR-411 Modulation in the Adult Brain of a Rat Model of Depression and After Fluoxetine Treatment
Published in Frontiers in behavioral neuroscience (07-08-2020)“…Depression is a chronic debilitating disorder predicted to affect around 20% of the world population. Both brain and peripheral changes, including neuroplastic…”
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Region-specific control of microglia by adenosine A2A receptors: uncoupling anxiety and associated cognitive deficits in female rats
Published in Glia (01-01-2019)“…Epidemiologic studies have provided compelling evidence that prenatal stress, through excessive maternal glucocorticoids exposure, is associated with…”
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Constitutive deficiency of the neurogenic hippocampal modulator AP2γ promotes anxiety-like behavior and cumulative memory deficits in mice from juvenile to adult periods
Published in eLife (03-12-2021)“…The transcription factor activating protein two gamma (AP2γ) is an important regulator of neurogenesis both during embryonic development as well as in the…”
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Beyond new neurons in the adult hippocampus: imipramine acts as a pro-astrogliogenic factor and rescues cognitive impairments induced by stress exposure
Published in Cells (Basel, Switzerland) (24-01-2022)“…Depression is a prevalent, socially burdensome disease. Different studies have demonstrated the important role of astrocytes in the pathophysiology of…”
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StressMatic: a novel automated system to induce depressive- and anxiety-like phenotype in rats
Published in Cells (Basel, Switzerland) (20-01-2023)“…Major depressive disorder (MDD) is a multidimensional psychiatric disorder that is estimated to affect around 350 million people worldwide. Generating valid…”
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The Sweet Drive Test: refining phenotypic characterization of anhedonic behavior in rodents
Published in Frontiers in behavioral neuroscience (07-03-2014)“…Measuring anhedonic behavior in rodents is a challenging task as current methods display only moderate sensitivity to detect anhedonic phenotype and,…”
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Selênio na germinação de sementes, no desenvolvimento e acúmulo de nutrientes em plântulas de pitaia in vitro (Hylocereus Costaricensis)
Published in Evidência (Joaçaba) (11-09-2024)“…A técnica de cultura de tecidos de plantas pode ser uma ferramenta eficaz de propagação da pitaieira, visto que, por meio dela as mudas são multiplicadas em…”
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Epigenetic (de)regulation of adult hippocampal neurogenesis: implications for depression
Published in Clinical epigenetics (01-11-2011)“…Adult neurogenesis represents a dynamic level of modulation upon the neuroplastic properties of the mature nervous system, that is essential to the homeostatic…”
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Immuno-Golgi as a tool for analyzing neuronal 3D-dendritic structure in phenotypically characterized neurons
Published in PloS one (12-03-2012)“…Characterization of neuronal dendritic structure in combination with the determination of specific neuronal phenotype or temporal generation is a challenging…”
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Iron Skin Staining: A Rare but Permanent Complication Following IV Iron Infusion
Published in Acta médica portuguesa (18-11-2024)Get full text
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Astrocytic plasticity at the dorsal dentate gyrus on an animal model of recurrent depression
Published in Neuroscience (01-02-2021)“…•Number of astrocytes is increased in the dentate gyrus after stress re-exposure.•Antidepressants prevent changes in astrocytic numbers induced by stress…”
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Region-specific control of microglia by adenosine A 2A receptors: uncoupling anxiety and associated cognitive deficits in female rats
Published in Glia (01-01-2019)“…Epidemiologic studies have provided compelling evidence that prenatal stress, through excessive maternal glucocorticoids exposure, is associated with…”
Get full text
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