Search Results - "Pinhal, Maria Aparecida"
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Hypericin in photobiological assays: An overview
Published in Photodiagnosis and photodynamic therapy (01-09-2021)“…•This review presents some important biological results obtained with hypericin in photodynamic therapy applications.•Highlight reviewed of the hypericin…”
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2
Resveratrol Decreases the Invasion Potential of Gastric Cancer Cells
Published in Molecules (Basel, Switzerland) (10-05-2022)“…The cancer-preventive agent Resveratrol (RSV) [3,5,4'-trihydroxytrans-stilbene] is a widely recognized antioxidant molecule with antitumoral potential against…”
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3
A clinical trial testing the efficacy of PDT in preventing amputation in diabetic patients
Published in Photodiagnosis and photodynamic therapy (01-09-2014)“…Highlights • We developed a low cost PDT protocol to treat the diabetic feet. • Rate of amputation was 35 times smaller in the PDT group. • Increased…”
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4
Heparan sulfate mediates trastuzumab effect in breast cancer cells
Published in BMC cancer (01-10-2013)“…Trastuzumab is an antibody widely used in the treatment of breast cancer cases that test positive for the human epidermal growth factor receptor 2 (HER2). Many…”
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MicroRNA-1252-5p Associated with Extracellular Vesicles Enhances Bortezomib Sensitivity in Multiple Myeloma Cells by Targeting Heparanase
Published in OncoTargets and therapy (01-01-2021)“…Multiple myeloma (MM) remains an incurable disease, and patient survival requires a better understanding of this malignancy's molecular aspects. Heparanase…”
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Crosstalk between tumor cells and lymphocytes modulates heparanase expression
Published in Journal of translational medicine (29-03-2019)“…Heparanase (HPSE) is an endo-beta-glucuronidase that degrades heparan sulfate (HS) chains on proteoglycans. The oligosaccharides generated by HPSE promote…”
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7
Immunohistochemistry as an Important Tool in Biomarkers Detection and Clinical Practice
Published in Biomarker Insights (2010)“…Leandro Luongo de Matos, Damila Cristina Trufelli, Maria Graciela Luongo de Matos and Maria Aparecida da Silva PinhalBiochemistry Department, Faculdade de…”
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MicroRNA‐mediated extracellular matrix remodeling in squamous cell carcinoma of the oral cavity
Published in Head & neck (01-08-2021)“…Background We evaluated microRNAs and extracellular matrix component profiles in squamous cell carcinoma of the oral cavity (OSCC) in comparison to healthy…”
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Development of the Tardivo Algorithm to Predict Amputation Risk of Diabetic Foot
Published in PloS one (17-08-2015)“…Diabetes is a chronic disease that affects almost 19% of the elderly population in Brazil and similar percentages around the world. Amputation of lower limbs…”
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The Profile of Heparanase Expression Distinguishes Differentiated Thyroid Carcinoma from Benign Neoplasms
Published in PloS one (21-10-2015)“…The search for a specific marker that could help to distinguish between differentiated thyroid carcinoma and benign lesions remains elusive in clinical…”
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Acquisition of anoikis resistance up-regulates syndecan-4 expression in endothelial cells
Published in PloS one (30-12-2014)“…Anoikis is a programmed cell death induced upon cell detachment from extracellular matrix, behaving as a critical mechanism in preventing adherent-independent…”
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Horizontal histological sections in the preliminary evaluation of basal cell carcinoma submitted to Mohs micrographic surgery
Published in Anais brasileiros de dermatología (01-11-2019)“…Mohs micrographic surgery is a surgical technique for the treatment of nonmelanoma skin cancer. Surgery begins by removing the visible tumor before excision of…”
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Birt-Hogg-Dubé syndrome with simultaneous hyperplastic polyposis of the gastrointestinal tract: case report and review of the literature
Published in BMC medical genetics (14-03-2020)“…Birt-Hogg-Dubé syndrome (BHDS) is a rare autosomal dominant genodermatosis characterized by benign growth of the hair follicles, the presence of pulmonary…”
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14
Reflectance confocal microscopy as a tool for screening surgical margins of basal cell carcinoma
Published in Anais brasileiros de dermatología (01-07-2018)“…Surgical excision of basal cell carcinoma with minimum margins requires serial assessment of layers by frozen histopathology in the case of Mohs micrographic…”
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Heparanase expression and glycosaminoglycans profile in renal cell carcinoma
Published in International journal of urology (01-11-2012)“…A better understanding of the molecular mechanisms of renal cell carcinogenesis could contribute to a decrease in the mortality rate of this disease. The aim…”
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Extracellular matrix alterations in the Peyronie’s disease
Published in Journal of advanced research (01-07-2017)“…[Display omitted] Peyronie’s disease is characterized by fibrous plaque formation of the tunica albuginea, causing penile deformity and fertility problems. The…”
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Inflammatory biomarkers in sera of patients with intervertebral disc degeneration
Published in Einstein (São Paulo, Brazil) (29-08-2019)“…To evaluate intervertebral disc levels of inflammatory factor (interleukin 6) and proteinase activity (cathepsin B) in patients with a degenerative disease and…”
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Dermatan sulfate epimerase 1 expression and mislocalization may interfere with dermatan sulfate synthesis and breast cancer cell growth
Published in Carbohydrate research (01-02-2020)“…Dermatan sulfate (DS) is a glycosaminoglycan (GAG) that is produced through the epimerization of the glucuronic acid on chondroitin sulfate into iduronic acid…”
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Immunohistochemical expression of heparanases 1 and 2 in benign tissue and in invasive neoplasia of the endometrium: a case-control study
Published in International journal of gynecological cancer (01-02-2015)“…Our purpose was to compare the expression of heparanase isoforms, in normal and in neoplastic endometrium. In a pioneering way, we sought to evaluate the…”
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Prospective Evaluation of Chondroitin Sulfate, Heparan Sulfate and Hyaluronic Acid in Prostate Cancer
Published in International Brazilian Journal of Urology (01-11-2018)“…The present study evaluates chondroitin sulfate (CS) and heparan sulfate (HS) in the urine and hyaluronic acid (HA) in the plasma of patients with prostate…”
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