Search Results - "Pines, G"

EGFRvIV: a previously uncharacterized oncogenic mutant reveals a kinase autoinhibitory mechanism by Pines, G, Huang, P H, Zwang, Y, White, F M, Yarden, Y

“…Tumor cells often subvert normal regulatory mechanisms of signal transduction. This study shows this principle by studying yet uncharacterized mutants of the…”
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Defective ubiquitinylation of EGFR mutants of lung cancer confers prolonged signaling by SHTIEGMAN, K, KOCHUPURAKKAL, B. S, BENJAMIN, S, CORSO, S, GAN, J, YOSEF, R. B, GIORDANO, S, YARDEN, Y, ZWANG, Y, PINES, G, STARR, A, VEXLER, A, CITRI, A, KATZ, M, LAVI, S, BEN-BASAT, Y

“…Several distinct mutations within the kinase domain of the epidermal growth factor receptor (EGFR) are associated with non-small cell lung cancer, but…”
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Deubiquitination of EGFR by Cezanne-1 contributes to cancer progression by Pareja, F, Ferraro, D A, Rubin, C, Cohen-Dvashi, H, Zhang, F, Aulmann, S, Ben-Chetrit, N, Pines, G, Navon, R, Crosetto, N, Köstler, W, Carvalho, S, Lavi, S, Schmitt, F, Dikic, I, Yakhini, Z, Sinn, P, Mills, G B, Yarden, Y

“…Once stimulated, the epidermal growth factor receptor (EGFR) undergoes self-phosphorylation, which, on the one hand, instigates signaling cascades, and on the…”
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The use of circular stapler for cervical esophagogastric anastomosis after esophagectomy: surgical technique and early postoperative outcome by Pines, G., Buyeviz, V., Machlenkin, S., Klein, Y., Laor, A., Kashtan, H.

“…SUMMARY Stapled esophagogastric anastomosis after esophagectomy is considered to be superior to traditional handsewn techniques. Linear staplers are usually…”
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Histidine 326 is critical for the function of GLT-1, a (Na+ + K+)-coupled glutamate transporter from rat brain by YUMIN ZHANG, PINES, G, KANNER, B. I

“…Removal of glutamate from the synaptic cleft is carried out by transporter molecules located in presynaptic nerve terminals and fine glial processes…”
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Contemporary outcomes of clinically low risk prostate cancer patients managed with robotic radical prostatectomy: A single surgeon experience by Palayapalayam Ganapathi, H, Ogaya-Pines, G, Rogers, T, Rocco, B, Patel, V

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Effect of enzyme replacement therapy on gammopathies in Gaucher disease by Brautbar, Ariel, Elstein, Deborah, Pines, Guy, Abrahamov, Aya, Zimran, Ari

“…Chronic antigenic stimulation by the abnormal lipid storage has been postulated to be the mechanism underlying anecdotal reports of monoclonal and polyclonal…”
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Structure and function of the sodium and potassium-coupled glutamate transporter from rat brain by Kanner, B I, Danbolt, N, Pines, G, Koepsell, H, Seeberg, E, Mathisen, J S

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Cloning and expression of a rat brain L-glutamate transporter by Pines, Gilia, Danbolt, Niels C, Bjørås, Magnar, Zhang, Yumin, Bendahan, Annie, Eide, Lars, Koepsell, Hermann, Storm-Mathisen, Jon, Seeberg, Erling, Kanner, Baruch I

“…Synaptic transmission of most vertebrate synapses is thought to be terminated by rapid transport of the neurotransmitter into presynaptic nerve terminals or…”
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Immobilization and characterization of Saccharomyces cerevisiae in crosslinked, prepolymerized polyacrylamide-hydrazide by Pines, G., Freeman, A.

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Purification and reconstitution of the sodium- and potassium-coupled glutamate transport glycoprotein from rat brain by Danbolt, Niels C, Pines, Gilia, Kanner, Baruch I

“…The sodium- and potassium-coupled L-glutamate transporter from rat brain has been purified to near homogeneity by reconstitution of transport as an assay,…”
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Glutamate 404 Is Involved in the Substrate Discrimination of GLT-1, a (Na+ + K+)-coupled Glutamate Transporter from Rat Brain (∗) by Pines, Gilia, Zhang, Yumin, Kanner, Baruch I.

“…Sodium-coupled glutamate transporters, located in the plasma membrane of nerve terminals and glial processes, serve to keep its extracellular glutamate…”
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PE46 - Contemporary outcomes of clinically low risk prostate cancer patients managed with robotic radical prostatectomy: A single surgeon experience by Palayapalayam Ganapathi, H., Ogaya-Pines, G., Rogers, T., Rocco, B., Patel, V.

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Counterflow of L-glutamate in plasma membrane vesicles and reconstituted preparations from rat brain by Pines, Gilia, Kanner, Baruch I

“…Membrane vesicles from rat brain exhibit sodium-dependent uptake of L-[3H]glutamate in the absence of any transmembrane ion gradients. The substrate…”
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Viral Infections and Phenotypic Heterogeneity in Gaucher Disease by Pines, Guy, Morag, Abraham, Elstein, Deborah, Abrahamov, Ayala, Zimran, Ari

“…ABSTRACT Gaucher disease, the most common lysosomal storage disorder, is remarkable for its tremendous phenotypic heterogeneity even among patients with the…”
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Glutamate 404 is involved in the substrate discrimination of GLT-1, a (Na super(+) + K super(+))-coupled glutamate transporter from rat brain by Pines, G, Zhang, Yumin, Kanner, B I

“…Sodium-coupled glutamate transporters, located in the plasma membrane of nerve terminals and glial processes, serve to keep its extracellular glutamate…”
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Histidine 326 is critical for the function of GLT-1, a (Na super(+) + K super(+))-coupled glutamate transporter from rat brain by Zhang, Y, Pines, G, Kanner, B I

“…Removal of glutamate from the synaptic cleft is carried out by transporter molecules located in presynaptic nerve terminals and fine glial processes…”
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Cloning and expression of a rat brain L-glutamate transporter by Pines, Gilia, Danbolt, Niels C, Bjørås, Magnar, Zhang, Yumin, Bendahan, Annie, Eide, Lars, Koepsell, Hermann, Storm-Mathisen, Jon, Seeberg, Erling, Kanner, Baruch I

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Real-world safety and effectiveness of dapagliflozin in people living with type 1 diabetes in Spain: The Dapa-ON multicenter retrospective study by Durán-Martínez, María, Azriel, Sharona, Doulatram-Gamgaram, Viyey Kishore, Moreno-Pérez, Óscar, Pinés-Corrales, Pedro J., Tejera-Pérez, Cristina, Merino-Torres, Juan Francisco, Brito-Sanfiel, Miguel, Chico, Ana, Marco, Amparo, García-Fernández, Elena, Martínez-Montoro, José Ignacio

“…To assess real-world safety and effectiveness of dapagliflozin in people living with type 1 diabetes mellitus (T1DM). We conducted a multicenter retrospective…”
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Interaction of carboxypeptidase A with monoclonal antibodies by Solomon, B, Moav, N, Pines, G, Katchalski-Katzir, E

“…Several mouse monoclonal antibodies to carboxypeptidase A (CPA) were prepared and purified, and their interaction with the enzyme was investigated. CPA is a…”
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