Search Results - "Pineda, Jose"
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The flavonoid quercetin ameliorates Alzheimer's disease pathology and protects cognitive and emotional function in aged triple transgenic Alzheimer's disease model mice
Published in Neuropharmacology (01-06-2015)“…Alzheimer's disease (AD) is the most common senile dementia in the world. Although important progress has been made in understanding the pathogenesis of AD,…”
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A 380 fW Leakage Data Retention Flip-Flop for Short Sleep Periods
Published in IEEE transactions on circuits and systems. II, Express briefs (01-07-2023)“…Data-retention flip-flops (DR-FF) provide an efficient state retention capability for any processor with frequent active-to-sleep mode transitions. This brief…”
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Alternative lengthening of telomeres renders cancer cells hypersensitive to ATR inhibitors
Published in Science (American Association for the Advancement of Science) (16-01-2015)“…Cancer cells rely on telomerase or the alternative lengthening of telomeres (ALT) pathway to overcome replicative mortality. ALT is mediated by recombination…”
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Editorial: Tumor microenvironment in primary brain cancers
Published in Frontiers in oncology (24-01-2023)Get full text
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Functional Topography of the Human Subthalamic Nucleus: Relevance for Subthalamotomy in Parkinson's Disease
Published in Movement disorders (01-02-2022)“…ABSTRACT Background The subthalamic nucleus (STN) is considered a key structure in motor, behavioral, and emotional control. Although identification of the…”
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The Relative Role of Mangroves on Wave Erosion Mitigation and Sediment Properties
Published in Estuaries and coasts (01-12-2019)“…Fringe mangroves face waves daily and are thought to protect against erosion in low wave energy sites and undergo erosion if exposed to high wave energy. We…”
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Striatal Blood–Brain Barrier Opening in Parkinson's Disease Dementia: A Pilot Exploratory Study
Published in Movement disorders (01-10-2022)“…Background Parkinson's disease (PD) exhibits a high prevalence of dementia as disease severity and duration progress. Focused ultrasound (FUS) has been applied…”
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Uncovering and resolving challenges of quantitative modeling in a simplified community of interacting cells
Published in PLoS biology (22-02-2019)“…Quantitative modeling is useful for predicting behaviors of a system and for rationally constructing or modifying the system. The predictive power of a model…”
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A multi-agent approach to the truck multi-drone routing problem
Published in Expert systems with applications (01-06-2022)“…•Truck-n-drone routing problem coded as a grid in which locations-agents can move.•Agent-based approach in which locations to be visited are the agents instead…”
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Twenty Years of Near/Sub-Threshold Design Trends and Enablement
Published in IEEE transactions on circuits and systems. II, Express briefs (01-01-2021)“…This brief surveys the past 20 years of near/sub-threshold digital integrated circuit design. Most of the chips have been highly characterized for voltage…”
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Blood-brain barrier opening with focused ultrasound in Parkinson’s disease dementia
Published in Nature communications (03-02-2021)“…MR-guided focused ultrasound (MRgFUS), in combination with intravenous microbubble administration, has been applied for focal temporary BBB opening in patients…”
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Changes in Pediatric ICU Utilization and Clinical Trends During the Coronavirus Pandemic
Published in Chest (01-08-2021)“…Children have been less affected by the COVID-19 pandemic, but its repercussions on pediatric illnesses may have been significant. This study examines the…”
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Scheduling a dual-resource flexible job shop with makespan and due date-related criteria
Published in Annals of operations research (01-08-2020)“…Current struggles for customer satisfaction in make-to-order companies focus on product customization and on-time delivery. For better management of demand-mix…”
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DUX4 is a common driver of immune evasion and immunotherapy failure in metastatic cancers
Published in eLife (03-06-2024)“…Cancer immune evasion contributes to checkpoint immunotherapy failure in many patients with metastatic cancers. The embryonic transcription factor DUX4 was…”
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Noninvasive modulation of human corticostriatal activity
Published in Proceedings of the National Academy of Sciences - PNAS (11-04-2023)“…Corticostriatal activity is an appealing target for nonpharmacological treatments of brain disorders. In humans, corticostriatal activity may be modulated with…”
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Notch and Wnt Signaling Modulation to Enhance DPSC Stemness and Therapeutic Potential
Published in International journal of molecular sciences (17-04-2023)“…The Dental Pulp of permanent human teeth is home to stem cells with remarkable multilineage differentiation ability: human Dental Pulp Stem Cells (DPSCs)…”
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Transcranial Magnetic Resonance-Guided Focused Ultrasound Thalamotomy in Essential Tremor: A Comprehensive Lesion Characterization
Published in Neurosurgery (01-08-2020)“…Abstract BACKGROUND Transcranial magnetic resonance-guided focused ultrasound (tcMRgFUS) thalamotomy is a novel and effective treatment for controlling tremor…”
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Multi-Level Optimization of an Ultra-Low Power BrainWave System for Non-Convulsive Seizure Detection
Published in IEEE transactions on biomedical circuits and systems (01-10-2021)“…We present a systematic evaluation and optimization of a complex bio-medical signal processing application on the BrainWave prototype system, targeted towards…”
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Molecular imaging to track Parkinson's disease and atypical parkinsonisms: New imaging frontiers
Published in Movement disorders (01-02-2017)“…ABSTRACT Molecular imaging has proven to be a powerful tool for investigation of parkinsonian disorders. One current challenge is to identify biomarkers of…”
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Structural characterization of the Extended Frontal Aslant Tract trajectory: A ML-validated laterality study in 3T and 7T
Published in NeuroImage (Orlando, Fla.) (15-11-2020)“…•The fractional anisotropy of the exFAT region is left-lateralized in the 3T sample.•The AFQ analyses detected a coherent set of laterality differences.•The ML…”
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