Search Results - "Pineda, Carlos T."
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Degradation of AMPK by a Cancer-Specific Ubiquitin Ligase
Published in Cell (12-02-2015)“…AMP-activated protein kinase (AMPK) is a master sensor and regulator of cellular energy status. Upon metabolic stress, AMPK suppresses anabolic and promotes…”
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Oncogenic MAGEA-TRIM28 ubiquitin ligase downregulates autophagy by ubiquitinating and degrading AMPK in cancer
Published in Autophagy (04-05-2015)“…Autophagy is commonly altered in cancer and has a complicated, but important role in regulation of tumor growth. Autophagy is often tumor suppressive in the…”
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Detection of in vivo enzyme activity with CatalyCEST MRI
Published in Magnetic resonance in medicine (01-03-2014)“…Purpose CatalyCEST MRI compares the detection of an enzyme‐responsive chemical exchange saturation transfer (CEST) agent with the detection of an unresponsive…”
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