Search Results - "Pind, Audur Anna Aradottir"
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The adjuvants dmLT and mmCT enhance humoral immune responses to a pneumococcal conjugate vaccine after both parenteral or mucosal immunization of neonatal mice
Published in Frontiers in immunology (20-01-2023)“…Immaturity of the neonatal immune system contributes to increased susceptibility to infectious diseases and poor vaccine responses. Therefore, better…”
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LT-K63 Enhances B Cell Activation and Survival Factors in Neonatal Mice That Translates Into Long-Lived Humoral Immunity
Published in Frontiers in immunology (23-10-2020)“…Adjuvants enhance magnitude and duration of immune responses induced by vaccines. In this study we assessed in neonatal mice if and how the adjuvant LT-K63…”
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Adjuvants Enhance the Induction of Germinal Center and Antibody Secreting Cells in Spleen and Their Persistence in Bone Marrow of Neonatal Mice
Published in Frontiers in immunology (26-09-2019)“…Immaturity of the immune system contributes to poor vaccine responses in early life. Germinal center (GC) activation is limited due to poorly developed…”
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Short Vi-polysaccharide abrogates T-independent immune response and hyporesponsiveness elicited by long Vi-CRM197 conjugate vaccine
Published in Proceedings of the National Academy of Sciences - PNAS (29-09-2020)“…Polysaccharide-protein conjugates have been developed to overcome the T-independent response, hyporesponsiveness to repeated vaccination, and poor…”
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A comparative study of adjuvants effects on neonatal plasma cell survival niche in bone marrow and persistence of humoral immune responses
Published in Frontiers in immunology (03-08-2022)“…The neonatal immune system is distinct from the immune system of older individuals rendering neonates vulnerable to infections and poor responders to…”
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Short Vi-polysaccharide abrogates T-independent immune response and hyporesponsiveness elicited by long Vi-CRM 197 conjugate vaccine
Published in Proceedings of the National Academy of Sciences - PNAS (29-09-2020)“…Polysaccharide-protein conjugates have been developed to overcome the T-independent response, hyporesponsiveness to repeated vaccination, and poor…”
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Journal Article