Search Results - "Pinault, Emilie"

The single EGF-like domain of mouse PAMR1 is modified by O-Glucose, O-Fucose and O-GlcNAc by Pennarubia, Florian, Germot, Agnès, Pinault, Emilie, Maftah, Abderrahman, Legardinier, Sébastien

“…Abstract Epidermal growth factor-like domains (EGF-LDs) of membrane and secreted proteins can be modified by N-glycans and/or potentially elongated O-linked…”
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A multi-omics investigation of tacrolimus off-target effects on a proximal tubule cell-line by Aouad, Hassan, Faucher, Quentin, Sauvage, François-Ludovic, Pinault, Emilie, Barrot, Claire-Cécile, Arnion, Hélène, Essig, Marie, Marquet, Pierre

“…Tacrolimus, an immunosuppressive drug prescribed to a majority of organ transplant recipients is nephrotoxic, through still unclear mechanisms. This study on a…”
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Revisiting the nature and pharmacodynamics of tacrolimus metabolites by Mevizou, Rudy, Aouad, Hassan, Sauvage, François-Ludovic, Arnion, Hélène, Pinault, Emilie, Bernard, Jean-Sébastien, Bertho, Gildas, Giraud, Nicolas, Alves de Sousa, Rodolphe, Lopez-Noriega, Adolfo, Di Meo, Florent, Campana, Mélanie, Marquet, Pierre

“…The toxicity of tacrolimus metabolites and their potential pharmacodynamic (PD) interactions with tacrolimus might respectively explain the surprising…”
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Charcot-Marie-Tooth-1A and sciatic nerve crush rat models: insights from proteomics by Msheik, Zeina, Durand, Stephanie, Pinault, Emilie, Caillaud, Martial, Vignaud, Laetitia, Billet, Fabrice, El Massry, Mohamed, Desmouliere, Alexis

“…The sensorimotor and histological aspects of peripheral neuropathies were already studied by our team in two rat models: the sciatic nerve crush and the…”
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Prebiotic Isomaltooligosaccharide Provides an Advantageous Fitness to the Probiotic Bacillus subtilis CU1 by Villéger, Romain, Pinault, Emilie, Vuillier-Devillers, Karine, Grenier, Karine, Landolt, Cornelia, Ropartz, David, Sol, Vincent, Urdaci, Maria C., Bressollier, Philippe, Ouk, Tan-Sothéa

“…Bacillus subtilis CU1 is a probiotic strain with beneficial effects on immune health in elderly subjects and diarrhea. Commercialized under spore form, new…”
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Mouse WIF1 Is Only Modified with O -Fucose in Its EGF-like Domain III Despite Two Evolutionarily Conserved Consensus Sites by Pennarubia, Florian, Pinault, Emilie, Al Jaam, Bilal, Brun, Caroline E, Maftah, Abderrahman, Germot, Agnès, Legardinier, Sébastien

“…The Wnt Inhibitory Factor 1 (Wif1), known to inhibit Wnt signaling pathways, is composed of a WIF domain and five EGF-like domains (EGF-LDs) involved in…”
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Improvement of Charcot-Marie-Tooth Phenotype with a Nanocomplex Treatment in Two Transgenic Models of CMT1A by El Massry, Mohamed, Msheik, Zeina, El Masri, Tarek, Ntoutoume, Gautier Ma Ndong, Vignaud, Laetitia, Richard, Laurence, Pinault, Emilie, Faye, Pierre-Antoine, Bregier, Frédérique, Marquet, Pierre, Favreau, Frédéric, Vallat, Jean-Michel, Billet, Fabrice, Sol, Vincent, Sturtz, Franck, Desmouliere, Alexis

“…Curcumin has been shown to exert beneficial effects in peripheral neuropathies. Despite its known biological activities, curcumin has unfavorable…”
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Alteration of the gut microbiome in mycophenolate-induced enteropathy: impacts on the profile of short-chain fatty acids in a mouse model by Jardou, Manon, Provost, Quentin, Brossier, Clarisse, Pinault, Émilie, Sauvage, François-Ludovic, Lawson, Roland

“…Mycophenolic acid (MPA) is the most widely used immunosuppressive drug in transplantation and for autoimmune diseases. Unfortunately, more than 30% of patients…”
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Heavy Chain Fibrillary Glomerulonephritis: A Case Report by Nasr, Samih H., Sirac, Christophe, Bridoux, Frank, Javaugue, Vincent, Bender, Sebastien, Rinsant, Alexia, Kaaki, Sihem, Pinault, Emilie, Dasari, Surendra, Alexander, Mariam P., Said, Samar M., Hogan, Jonathan J., Dispenzieri, Angela, Touchard, Guy, McPhail, Ellen D., Leung, Nelson

“…Heavy chain amyloidosis and heavy chain deposition disease are the only known kidney diseases caused by the deposition of truncated immunoglobulin heavy…”
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Lysine Analogue of Polymyxin B as a Significant Opportunity for Photodynamic Antimicrobial Chemotherapy by Le Guern, Florent, Ouk, Tan-Sothea, Ouk, Catherine, Vanderesse, Regis, Champavier, Yves, Pinault, Emilie, Sol, Vincent

“…In order to highlight the potential of photodynamic antimicrobial chemotherapy in case of infections by antibiotic resistant-strains, a new antimicrobial…”
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8-Alkynyl-3-nitroimidazopyridines display potent antitrypanosomal activity against both T. b. brucei and cruzi by Fersing, Cyril, Boudot, Clotilde, Castera-Ducros, Caroline, Pinault, Emilie, Hutter, Sébastien, Paoli-Lombardo, Romain, Primas, Nicolas, Pedron, Julien, Seguy, Line, Bourgeade-Delmas, Sandra, Sournia-Saquet, Alix, Stigliani, Jean-Luc, Brossas, Jean-Yves, Paris, Luc, Valentin, Alexis, Wyllie, Susan, Fairlamb, Alan H., Boutet-Robinet, Élisa, Corvaisier, Sophie, Since, Marc, Malzert-Fréon, Aurélie, Destere, Alexandre, Mazier, Dominique, Rathelot, Pascal, Courtioux, Bertrand, Azas, Nadine, Verhaeghe, Pierre, Vanelle, Patrice

“…An antikinetoplastid pharmacomodulation study was done at position 8 of a previously identified pharmacophore in 3-nitroimidazo[1,2-a]pyridine series. Twenty…”
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Are cysteine, glutathione and phytochelatins responses of Myriophyllum alterniflorum to copper and arsenic stress affected by trophic conditions? by Krayem, Maha, Pinault, Emilie, Deluchat, Veronique, Labrousse, Pascal

“…The aim of this article is to study the impact of both copper (Cu 2+ ) and arsenic (As (V)) at 100 µg/L, with each element being combined with trophic…”
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POFUT1-mediated O-fucosylation of glycoproteins expressed in the baculovirus Sf9 insect cell expression system by Haymour, Layla, Pennarubia, Florian, Le Faou, Claire Colombel, Pinault, Emilie, Germot, Agnès, Maftah, Abderrahman, Legardinier, Sébastien

“…The baculovirus-insect cell expression system allows addition of O-fucose to EGF-like domains of glycoproteins, following the action of the protein…”
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In vitro acellular method to reveal O-fucosylation on EGF-like domains by Pennarubia, Florian, Pinault, Emilie, Maftah, Abderrahman, Legardinier, Sébastien

“…Abstract One hundred human proteins have one or more EGF-like domains (EGF-LD) bearing the O-fucosylation consensus motif C2X4(S/T)C3 but to date, only a few…”
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Posttranslational-modifications of human-serum-albumin analysis by a top-down approach validated by a comprehensive bottom-up analysis by Rahali, Mohamad-Ali, Lakis, Roy, Sauvage, François-Ludovic, Pinault, Emilie, Marquet, Pierre, Saint-Marcoux, Franck, El Balkhi, Souleiman

“…•HAS, the most abundant protein in blood serum, has several physiological functions such as binding, transport, and detoxification of molecules.•HSA undergoes…”
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Absolute Quantification of Human Serum Albumin Isoforms by Internal Calibration Based on a Top-Down LC-MS Approach by Lakis, Roy, Sauvage, François-Ludovic, Pinault, Emilie, Marquet, Pierre, Saint-Marcoux, Franck, El Balkhi, Souleiman

“…Well-characterized biomarkers using reliable quantitative methods are essential for the management of various pathologies such as diabetes, kidney, and liver…”
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Profiling and seasonal variation of chemical constituents from Pseudotsuga menziesii wood by Mbakidi-Ngouaby, Henri, Pinault, Emilie, Gloaguen, Vincent, Costa, Guy, Sol, Vincent, Millot, Marion, Mambu, Lengo

“…[Display omitted] •57 secondary metabolites are identified in Douglas-fir by LC–MS/MS.•Distribution of extractives between heartwood, sapwood and the…”
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Gut microbiota biotransformation of drug glucuronides leading to gastrointestinal toxicity: Therapeutic potential of bacterial β-glucuronidase inhibition in mycophenolate-induced enteropathy by Brossier, Clarisse, Jardou, Manon, Janaszkiewicz, Angelika, Firoud, Djouher, Petit, Isy, Arnion, Hélène, Pinault, Emilie, Sauvage, François-Ludovic, Druilhe, Anne, Picard, Nicolas, Di Meo, Florent, Marquet, Pierre, Lawson, Roland

“…Drug-induced enteropathy is often associated with the therapeutic use of certain glucuronidated drugs. One such drug is mycophenolic acid (MPA), a…”
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Semi-synthetic human albumin isoforms: Production, structure, binding capacities and influence on a routine laboratory test by Lakis, Roy, Sauvage, François-Ludovic, Pinault, Emilie, Marquet, Pierre, Saint-Marcoux, Franck, El Balkhi, Souleiman

“…Human Serum Albumin (HSA) undergoes Post-Translational-Modifications (PTMs) leading to isoforms affecting its oncotic and non-oncotic properties. HSA is…”
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Functional Characterization of POFUT1 Variants Associated with Colorectal Cancer by Deschuyter, Marlène, Pennarubia, Florian, Pinault, Emilie, Legardinier, Sébastien, Maftah, Abderrahman

“…Background: Protein O-fucosyltransferase 1 (POFUT1) overexpression, which is observed in many cancers such as colorectal cancer (CRC), leads to a NOTCH…”
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